Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
CD69 969 BENDAMUSTINE CHEMBL487253 CGI

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
CD69 rs11052877 A tocilizumab efficacy yes Patients had previously been treated with disease-modifying anti rheumatic drugs (DMARD), and 68.4% had tried at least one Biological therapy. Tocilizumab was administered intravenously. Concomitant glucocorticoid and DMARD was prescribed in 92.4% and 55.7% of patients, respectively. Efficacy measured low disease activity at 6 months. Allele A is associated with increased response to tocilizumab in people with Arthritis, Rheumatoid as compared to allele G. 27339827 1448112479