PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
CDH1	4	TRIM25	5	bioid	Guo Z (2014)	1
TRAF1	0	RB1CC1	9	affinity chromatography technology	Huttlin EL (2017)	1
SESN2	3	ATG13	0	affinity chromatography technology, affinity chromatography technology	Ro SH (2014), Ro SH (2014)	2
TP53	0	RPA1	0	pull down, affinity chromatography technology, affinity chromatography technology, pull down	Romanova LY (2004), Romanova LY (2004), Riva F (2001), Glanzer JG (2013)	4
TCEAL4	0	RB1CC1	9	affinity chromatography technology	Hein MY (2015)	1
VAPA	1	VAPB	2	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nishimura Y (1999), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	4
PTK2	2	TP53	0	affinity chromatography technology, pull down, imaging technique	Lim ST (2008), Lim ST (2008), Chen TC (2014)	3
RB1CC1	9	BLID	0	two hybrid	Arroyo R (2015)	1
RB1CC1	9	RPA2	0	affinity chromatography technology	Behrends C (2010)	1
TRAF2	1	RB1CC1	9	affinity chromatography technology	Gan B (2006)	1
TP53	0	SMARCB1	1	pull down, affinity chromatography technology, pull down, biochemical	Lee D (2002), Lee D (2002), Lee D (2002), Lee D (2002)	4
MAP1LC3C	0	ATG16L1	1	affinity chromatography technology	Behrends C (2010)	1
GABARAP	0	ATG13	0	affinity chromatography technology, unspecified method, two hybrid	Alemu EA (2012), Alemu EA (2012), Fujita N (2013)	3
TRAF2	1	UBC	7	enzymatic study, enzymatic study	Liu J (2011), Kanayama A (2004)	2
RPA1	0	RPA2	0	affinity chromatography technology, x-ray crystallography, affinity chromatography technology, biochemical, biochemical, two hybrid, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Shao RG (1999), Bochkareva E (2002), Gong Z (2011), Havugimana PC (2012), Kristensen AR (2012), Ghospurkar PL (2014), Huttlin EL (2015), Wan C (2015), Hein MY (2015), Elia AE (2015), Elia AE (2015), Huttlin EL (2017), Feeney L (2017)	13
DBNL	2	RB1CC1	9	affinity chromatography technology	Ewing RM (2007)	1
TP53	0	RNF20	9	pull down, affinity chromatography technology	Kim J (2005), Kim J (2005)	2
MAP1LC3C	0	UBC	7	imaging technique	Liu X (2017)	1
GABARAPL1	0	ULK1	8	affinity chromatography technology	Alemu EA (2012)	1
RIPK4	0	RB1CC1	9	affinity chromatography technology	Rodriguez J (2016)	1
RFWD2	0	RB1CC1	9	two hybrid, pull down, protein complementation assay	Kobayashi S (2013), Kobayashi S (2013), Kobayashi S (2013)	3
SGO1	2	RB1CC1	9	affinity chromatography technology	Hein MY (2015)	1
UBC	7	BAP1	4	pull down, pull down, pull down, pull down	Duerksen-Hughes PJ (1989), Daou S (2015), Kwasna D (2018), Hanpude P (2017)	4
RB1CC1	9	ATG5	0	affinity chromatography technology	Gammoh N (2013)	1
TRAF1	0	TBK1	1	affinity chromatography technology, affinity chromatography technology	Greenfeld H (2015), Huttlin EL (2017)	2
TP53	0	UBC	7	affinity chromatography technology, affinity chromatography technology	Ayroldi E (2014), Ke JY (2014)	2
RIPK4	0	MADD	8	affinity chromatography technology	Rodriguez J (2016)	1
ATG5	0	CALCOCO2	0	pull down	Fracchiolla D (2016)	1
TRIM25	5	CTNNB1	30	affinity chromatography technology	Choudhury NR (2017)	1
SESN2	3	RB1CC1	9	affinity chromatography technology, affinity chromatography technology	Ro SH (2014), Ro SH (2014)	2
RNF111	2	SKI	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nagano Y (2007), Le Scolan E (2008), Erker Y (2013)	3
GABARAPL1	0	GABARAP	0	affinity chromatography technology	Behrends C (2010)	1
CDH1	4	VAPA	1	bioid	Guo Z (2014)	1
CALCOCO2	0	RB1CC1	9	two hybrid	Wang J (2011)	1
RB1CC1	9	ATG101	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Behrends C (2010), Hosokawa N (2009), Hosokawa N (2009)	3
RB1CC1	9	EPSTI1	0	two hybrid	Arroyo R (2015)	1
DYRK2	1	TBK1	1	affinity chromatography technology, affinity chromatography technology	An T (2015), An T (2015)	2
ATG16L1	1	ULK1	8	affinity chromatography technology	Gammoh N (2013)	1
RB1CC1	9	NSD3	6	two hybrid	Arroyo R (2015)	1
TP53	0	RPA2	0	affinity chromatography technology	Li X (2015)	1
RB1CC1	9	LYPD3	0	two hybrid	Arroyo R (2015)	1
SKI	3	SKIL	3	pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Cohen SB (1999), Cohen SB (1999), Tan R (2006), He J (2003), Ikeuchi Y (2014)	5
PINK1	2	UBC	7	enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Koyano F (2014), Kane LA (2014), Kane LA (2014), Shiba-Fukushima K (2014), Okatsu K (2015), Fiesel FC (2015), Ando M (2017), Klosowiak JL (2016)	8
PRKAA2	1	MAP3K5	1	affinity chromatography technology	Behrends C (2010)	1
ATG101	1	ATG13	0	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Behrends C (2010), Behrends C (2010), Fujita N (2013), Hosokawa N (2009), Hosokawa N (2009), Hosokawa N (2009)	6
MAP1LC3C	0	ATG13	0	affinity chromatography technology	Alemu EA (2012)	1
RB1CC1	9	SAFB	3	affinity chromatography technology	Behrends C (2010)	1
HUWE1	22	RB1CC1	9	affinity chromatography technology	Hein MY (2015)	1
WASHC3	2	ULK1	8	affinity chromatography technology	Huttlin EL (2017)	1
SAFB	3	SAFB2	3	two hybrid, affinity chromatography technology, biochemical	Townson SM (2003), Townson SM (2003), Wan C (2015)	3
RB1CC1	9	TP53	0	affinity chromatography technology	Chano T (2010)	1
ATG101	1	ULK1	8	affinity chromatography technology, affinity chromatography technology	Hosokawa N (2009), Rui YN (2015)	2
WASHC3	2	ATG13	0	affinity chromatography technology	Huttlin EL (2017)	1
RB1CC1	9	ERRFI1	1	two hybrid	Arroyo R (2015)	1
TBK1	1	TRAF2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Bouwmeester T (2004), Bonnard M (2000), Behrends C (2010), Li S (2011), Li S (2011), Shen RR (2012), Zhang W (2010), Huttlin EL (2017), Fang R (2017), Fang R (2017)	10
ULK1	8	SESN2	3	affinity chromatography technology, pull down	Ro SH (2014), Ro SH (2014)	2
TRIM25	5	RBMX	2	affinity chromatography technology, affinity chromatography technology	Choudhury NR (2017), Choudhury NR (2017)	2
RNF111	2	SKIL	3	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Levy L (2007), Levy L (2007), Nagano Y (2007), Erker Y (2013)	4
UBC	7	ATG16L1	1	affinity chromatography technology, pull down, pull down	Fujita N (2013), Fujita N (2013), Ver Heul AM (2013)	3
RB1CC1	9	RBMX	2	affinity chromatography technology	Behrends C (2010)	1
VHL	0	VAPB	2	pull down	Lai Y (2012)	1
UBC	7	CALCOCO2	0	pull down, affinity chromatography technology, two hybrid, pull down, x-ray crystallography, pull down, affinity chromatography technology, imaging technique, pull down, imaging technique	Fenner BJ (2009), Fenner BJ (2009), Rolland T (2014), Tumbarello DA (2015), Xie X (2015), Xie X (2015), Xie X (2015), Xie X (2015), Ordureau A (2015), Minowa-Nozawa A (2017)	10
CCDC8	1	RBMX	2	affinity chromatography technology	Hanson D (2014)	1
GABARAPL1	0	RB1CC1	9	affinity chromatography technology	Alemu EA (2012)	1
PRKAA2	1	PRKAB2	0	affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology	Behrends C (2010), Behrends C (2010), Moreno D (2009), Moreno D (2009), Corominas R (2014), Rolland T (2014), Wong KA (2006), Huttlin EL (2017)	8
RB1CC1	9	TBK1	1	affinity chromatography technology, genetic interference	Behrends C (2010), Goodwin JM (2017)	2
FAM221B	0	RB1CC1	9	affinity chromatography technology	Huttlin EL (2017)	1
HSBP1	0	WASHC3	2	two hybrid, two hybrid, affinity chromatography technology	Rual JF (2005), Rolland T (2014), Huttlin EL (2017)	3
FAM221B	0	ATG101	1	affinity chromatography technology	Huttlin EL (2017)	1
ATG16L1	1	ATG5	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, biochemical, affinity chromatography technology, x-ray crystallography, biochemical, x-ray crystallography, two hybrid, pull down, affinity chromatography technology	Behrends C (2010), Behrends C (2010), Chen D (2012), Chen D (2012), Ravikumar B (2010), Itoh T (2008), Kristensen AR (2012), Gammoh N (2013), Otomo C (2013), Wan C (2015), Kim JH (2014), Kim JH (2014), Kim JH (2014), Zheng Y (2017)	14
CCDC8	1	UBC	7	affinity chromatography technology	Hanson D (2014)	1
RB1CC1	9	MAP3K5	1	affinity chromatography technology, affinity chromatography technology	Gan B (2006), Gan B (2006)	2
PRKAB2	0	CALCOCO2	0	two hybrid	Corominas R (2014)	1
RB1CC1	9	GREB1	8	two hybrid	Arroyo R (2015)	1
RB1CC1	9	HBP1	1	two hybrid	Arroyo R (2015)	1
CDH1	4	VAPB	2	bioid	Guo Z (2014)	1
RB1CC1	9	GLCE	0	two hybrid	Arroyo R (2015)	1
SMARCB1	1	RB1CC1	9	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chano T (2010), Chano T (2010), Chano T (2010), Ochi Y (2011)	4
TRIM25	5	PTK2	2	affinity chromatography technology	Choudhury NR (2017)	1
TRIM25	5	SKI	3	affinity chromatography technology	Choudhury NR (2017)	1
TRIM25	5	RPA1	0	affinity chromatography technology	Pauli EK (2014)	1
TP53	0	HUWE1	22	pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Chen D (2005), Chen D (2005), Chen D (2005), Chen D (2005), Rolfo A (2012), Rolfo A (2012)	6
ATG13	0	RB1CC1	9	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Behrends C (2010), Behrends C (2010), Hosokawa N (2009)	3
DYRK2	1	RPA1	0	affinity chromatography technology	Maddika S (2009)	1
ATG16L1	1	ATG13	0	affinity chromatography technology	Gammoh N (2013)	1
RB1CC1	9	MRC2	3	two hybrid	Arroyo R (2015)	1
SGTB	2	RB1CC1	9	affinity chromatography technology	Hein MY (2015)	1
RB1CC1	9	PTK2	2	pull down, affinity chromatography technology	Ueda H (2000), Ueda H (2000)	2
NANOG	0	HUWE1	22	affinity chromatography technology	Oliviero G (2015)	1
GABARAP	0	ULK2	0	unspecified method	Alemu EA (2012)	1
VAPA	1	TACC1	2	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Huttlin EL (2017)	2
CDH1	4	RB1CC1	9	bioid	Guo Z (2014)	1
CALCOCO2	0	TBKBP1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Thurston TL (2009), Li S (2011), Huttlin EL (2017)	3
TRIM25	5	HUWE1	22	affinity chromatography technology	Choudhury NR (2017)	1
MAP1LC3C	0	GABARAP	0	affinity chromatography technology	Behrends C (2010)	1
GABARAP	0	ATG101	1	two hybrid	Fujita N (2013)	1
RB1CC1	9	WIF1	0	two hybrid	Arroyo R (2015)	1
RB1CC1	9	HSBP1	0	affinity chromatography technology	Behrends C (2010)	1
RB1CC1	9	IL24	0	two hybrid	Arroyo R (2015)	1
ERCC6L	3	RB1CC1	9	affinity chromatography technology	Ewing RM (2007)	1
RIPK4	0	TP53	0	affinity chromatography technology	Rodriguez J (2016)	1
RB1CC1	9	ITIH5	1	two hybrid	Arroyo R (2015)	1
TACC1	2	RB1CC1	9	affinity chromatography technology	Hein MY (2015)	1
RB1CC1	9	IL13RA2	0	two hybrid	Arroyo R (2015)	1
UBC	7	ATG13	0	affinity chromatography technology	Matsumoto M (2005)	1
UBC	7	RNF20	9	affinity chromatography technology	Bish RA (2007)	1
MOB4	0	RB1CC1	9	affinity chromatography technology	Ewing RM (2007)	1
WASHC3	2	RB1CC1	9	affinity chromatography technology	Huttlin EL (2017)	1
CDH1	4	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Davies G (2001), Kucerova D (2001), Oyama T (1994), Hazan RB (1997), Kinch MS (1995), Jiang MC (2002), Hazan RB (1998), Bonvini P (2001), Li Y (1998), Wendeler MW (2004), Shibata T (2003), Piedra J (2003), Oneyama C (2002), Navarro P (1993), Takahashi K (1997), Dobrosotskaya IY (2000), Dobrosotskaya IY (2000), Geng L (2000), Shibamoto S (1995), Rao RK (2002), Rao RK (2002), Huber AH (2001), Schmeiser K (1999), Pai R (2008), Tu LC (2007), Tu LC (2007), Smyth D (2012), Xue B (2005), Xue B (2005), Catimel B (2005), Huang Z (2012), Yan HX (2006), Yan HX (2006), Figueiredo J (2013), Ponce E (2014), Ponce E (2014), Ponce E (2014), Ribeiro AS (2013), Pinheiro H (2012), Geng F (2012), Lee HK (2007), Guo Z (2014)	42
HUWE1	22	RPA2	0	affinity chromatography technology	Thompson JW (2014)	1
VHL	0	TP53	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Roe JS (2006), Roe JS (2006), Roe JS (2006), Lai Y (2011), Lai Y (2011)	5
DLG3	1	PTK2B	6	affinity chromatography technology, affinity chromatography technology, pull down	Seabold GK (2003), Seabold GK (2003), Seabold GK (2003)	3
CTNNB1	30	RB1CC1	9	two hybrid, affinity chromatography technology, affinity chromatography technology	Choi JD (2012), Choi JD (2012), Choi JD (2012)	3
MTMR4	1	RB1CC1	9	affinity chromatography technology	St-Denis N (2016)	1
ULK1	8	PRKAB2	0	affinity chromatography technology	Behrends C (2010)	1
MAP1LC3C	0	ULK1	8	affinity chromatography technology	Alemu EA (2012)	1
DUPD1	0	RB1CC1	9	bioid	St-Denis N (2016)	1
RB1CC1	9	SKIL	3	affinity chromatography technology	Koinuma D (2011)	1
DENR	2	ATG13	0	affinity chromatography technology	Huttlin EL (2017)	1
VHL	0	UBC	7	pull down	Lisztwan J (1999)	1
ULK2	0	RB1CC1	9	affinity chromatography technology	Behrends C (2010)	1
VAPB	2	UBC	7	affinity chromatography technology	Baron Y (2014)	1
CDH1	4	DBNL	2	bioid	Guo Z (2014)	1
ULK1	8	RB1CC1	9	affinity chromatography technology, affinity chromatography technology	Behrends C (2010), Rui YN (2015)	2
CALCOCO2	0	RPA2	0	two hybrid	Wang J (2011)	1
GABARAPL1	0	ATG13	0	affinity chromatography technology	Alemu EA (2012)	1
RNF111	2	UBC	7	enzymatic study	Wright JD (2016)	1
VHL	0	RB1CC1	9	two hybrid	Bex C (2007)	1
TRAF1	0	UBC	7	affinity chromatography technology	Greenfeld H (2015)	1
RB1CC1	9	MADD	8	two hybrid	Arroyo R (2015)	1
RIPK4	0	HUWE1	22	affinity chromatography technology	Rodriguez J (2016)	1
EXOC1	3	RB1CC1	9	two hybrid	Bodemann BO (2011)	1
SYCE3	0	RB1CC1	9	affinity chromatography technology	Huttlin EL (2017)	1
RPA2	0	UBC	7	affinity chromatography technology	Marechal A (2014)	1
FAM221B	0	ATG13	0	affinity chromatography technology	Huttlin EL (2017)	1
RB1CC1	9	RNF20	9	two hybrid	Arroyo R (2015)	1
ULK1	8	ULK2	0	genetic interference	Goodwin JM (2017)	1
ULK1	8	ATG13	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Dunlop EA (2011), Nazio F (2013), Nazio F (2013), Hosokawa N (2009), Li J (2015), Dunlop EA (2014), Rui YN (2015)	7
PRKAB2	0	RB1CC1	9	affinity chromatography technology	Behrends C (2010)	1
TP53	0	TCEAL4	0	affinity chromatography technology	Fogeron ML (2013)	1
RB1CC1	9	RNF111	2	affinity chromatography technology	Koinuma D (2011)	1
PRKAB2	0	MAP3K5	1	affinity chromatography technology	Behrends C (2010)	1
TRIM25	5	ULK1	8	affinity chromatography technology	Choudhury NR (2017)	1
SAFB2	3	TP53	0	affinity chromatography technology	Peidis P (2011)	1
RPA1	0	UBC	7	affinity chromatography technology	Marechal A (2014)	1
TBKBP1	2	RB1CC1	9	affinity chromatography technology, pull down	Li S (2011), Li S (2011)	2
RB1CC1	9	UMPS	4	two hybrid	Arroyo R (2015)	1
MAP1LC3C	0	CALCOCO2	0	affinity chromatography technology, pull down, x-ray crystallography, two hybrid, affinity chromatography technology	von Muhlinen N (2012), von Muhlinen N (2012), von Muhlinen N (2012), Tumbarello DA (2015), Verlhac P (2015)	5
VAPB	2	RB1CC1	9	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MAP1LC3C	0	RB1CC1	9	affinity chromatography technology	Behrends C (2010)	1
RB1CC1	9	SKI	3	affinity chromatography technology, affinity chromatography technology	Koinuma D (2011), Koinuma D (2011)	2
ULK1	8	GABARAP	0	affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, unspecified method, affinity chromatography technology	Ewing RM (2007), Okazaki N (2000), Okazaki N (2000), Alemu EA (2012), Alemu EA (2012), Dunlop EA (2014)	6
RB1CC1	9	PSMC3IP	0	two hybrid	Arroyo R (2015)	1
TBK1	1	TBKBP1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bouwmeester T (2004), Li S (2011), Li S (2011), Ryzhakov G (2007), Ryzhakov G (2007), Ryzhakov G (2007), Seo S (2013), Richter B (2016)	8
CDK19	1	RB1CC1	9	affinity chromatography technology	Ewing RM (2007)	1
TRAF1	0	TRAF2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe, pull down, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, imaging technique, affinity chromatography technology, affinity chromatography technology	Bouwmeester T (2004), Takeuchi M (1996), Li S (2011), Li S (2011), Fries KL (1999), He L (2004), Zheng C (2010), Zheng C (2010), Relaix F (1998), Relaix F (1998), Jang HD (2001), Fotin-Mleczek M (2004), Pullen SS (1998), Wicovsky A (2009), Rothe M (1994), Rothe M (1994), Chen TC (2014), Greenfeld H (2015), Huttlin EL (2017)	19
DYRK2	1	RB1CC1	9	affinity chromatography technology	Varjosalo M (2013)	1
RBMX	2	SAFB	3	biochemical	Havugimana PC (2012)	1
NANOG	0	RB1CC1	9	affinity chromatography technology	Oliviero G (2015)	1
PINK1	2	RB1CC1	9	affinity chromatography technology	Murata H (2013)	1
PRKAA2	1	ULK1	8	affinity chromatography technology	Behrends C (2010)	1
VHL	0	HUWE1	22	affinity chromatography technology	Zhang C (2016)	1
CDH1	4	UBC	7	bioid	Guo Z (2014)	1
TRIM25	5	RB1CC1	9	affinity chromatography technology	Choudhury NR (2017)	1
RB1CC1	9	SAFB2	3	affinity chromatography technology	Behrends C (2010)	1
RB1CC1	9	SYN1	1	two hybrid	Arroyo R (2015)	1
CALCOCO2	0	GABARAPL1	0	two hybrid, two hybrid, affinity chromatography technology	Rual JF (2005), Rolland T (2014), Verlhac P (2015)	3
VAPB	2	TACC1	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TP53	0	CCDC8	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dai C (2011), Dai C (2011), Dai C (2011), Dai C (2011), Fogeron ML (2013), Hanson D (2014), Hanson D (2014)	7
RB1CC1	9	BAP1	4	two hybrid	Arroyo R (2015)	1
UBC	7	HUWE1	22	pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, enzymatic study	Nathan JA (2013), Bish RA (2007), Thompson JW (2014), Kristariyanto YA (2015), Zhang X (2017), Michel MA (2017)	6
RB1CC1	9	THRSP	0	two hybrid	Arroyo R (2015)	1
RFWD2	0	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dornan D (2006), Dornan D (2004), Dornan D (2004), Dornan D (2004), Dornan D (2004), Choi HH (2011), Yamada T (2013), Zou S (2016)	8
RB1CC1	9	SMCR8	6	affinity chromatography technology	Behrends C (2010)	1
GABARAP	0	RB1CC1	9	affinity chromatography technology, unspecified method	Alemu EA (2012), Alemu EA (2012)	2
MAP1LC3C	0	ATG5	0	affinity chromatography technology	Behrends C (2010)	1
CCDC8	1	TRIM25	5	affinity chromatography technology	Hanson D (2014)	1
WASHC3	2	RNF20	9	affinity chromatography technology	Huttlin EL (2017)	1
CCDC8	1	CTNNB1	30	affinity chromatography technology	Hanson D (2014)	1
RB1CC1	9	YLPM1	6	affinity chromatography technology	Behrends C (2010)	1
HUWE1	22	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Thompson JW (2014), Dominguez-Brauer C (2017), Dominguez-Brauer C (2017), Dominguez-Brauer C (2017)	4
SMARCB1	1	VHL	0	genetic interference	Shen JP (2017)	1
VAPA	1	RB1CC1	9	affinity chromatography technology	Huttlin EL (2017)	1
TBK1	1	CALCOCO2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Thurston TL (2009), Li S (2011), Li S (2011), Li S (2011), Li S (2011), Huttlin EL (2017)	6
TRAF1	0	MAP3K5	1	affinity chromatography technology	Nishitoh H (1998)	1
TP53	0	UMPS	4	genetic interference	Xie L (2013)	1
PRKAB2	0	TRAF2	1	two hybrid, two hybrid, two hybrid	Corominas R (2014), Rolland T (2014), Yu H (2011)	3
CCDC8	1	RPA1	0	affinity chromatography technology	Hanson D (2014)	1
TRAF2	1	CALCOCO2	0	two hybrid	Rual JF (2005)	1
TRIM25	5	UBC	7	enzymatic study	Sanchez JG (2016)	1
ATG101	1	RPA1	0	affinity chromatography technology	Behrends C (2010)	1
RBMX	2	SAFB2	3	affinity chromatography technology	Huttlin EL (2015)	1
RB1CC1	9	UBC	7	pull down	Choi JD (2012)	1
RB1CC1	9	RPA1	0	affinity chromatography technology	Behrends C (2010)	1
RB1CC1	9	PTK2B	6	affinity chromatography technology, pull down, two hybrid, genetic interference	Ueda H (2000), Ueda H (2000), Ueda H (2000), Ueda H (2000)	4
RB1CC1	9	VPS45	0	two hybrid	Arroyo R (2015)	1
CCDC8	1	TBK1	1	affinity chromatography technology	Hanson D (2014)	1
CCDC8	1	HUWE1	22	affinity chromatography technology	Hanson D (2014)	1
TRIM25	5	PSMC3IP	0	affinity chromatography technology	Choudhury NR (2017)	1
PRKAA2	1	RB1CC1	9	affinity chromatography technology	Behrends C (2010)	1
VHL	0	MOB4	0	affinity chromatography technology	Ewing RM (2007)	1
GABARAP	0	CALCOCO2	0	affinity chromatography technology	Verlhac P (2015)	1
TRIM25	5	GREB1	8	affinity chromatography technology	Choudhury NR (2017)	1
DENR	2	RB1CC1	9	affinity chromatography technology	Huttlin EL (2017)	1
CCDC8	1	RB1CC1	9	affinity chromatography technology	Hanson D (2014)	1
RB1CC1	9	ATG16L1	1	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Fujita N (2013), Fujita N (2013), Gammoh N (2013), Gammoh N (2013), Gammoh N (2013), Gammoh N (2013), Dooley HC (2014)	7
DLG3	1	RB1CC1	9	affinity chromatography technology	Hein MY (2015)	1
TRAF2	1	MAP3K5	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Nishitoh H (1998), Hoeflich KP (1999), Gan B (2006), Kolliputi N (2009), Fujino G (2007), Fujino G (2007), Wu Y (2006), Zhang H (2004), Hwang SG (2014), Yoon KW (2009), Yoon KW (2009)	11
SKI	3	TP53	0	affinity chromatography technology	Inoue Y (2011)	1
WASHC3	2	ATG101	1	affinity chromatography technology	Huttlin EL (2017)	1
SAFB	3	TP53	0	affinity chromatography technology, affinity chromatography technology	Peidis P (2011), Peidis P (2011)	2
CTNNB1	30	RBMX	2	affinity chromatography technology	Sato S (2005)	1
TRIM25	5	RFWD2	0	affinity chromatography technology	Choudhury NR (2017)	1
TRIM25	5	MTMR4	1	affinity chromatography technology	Choudhury NR (2017)	1