PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
RBPMS	0	C1orf94	1	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
CDC5L	2	DDX19B	2	affinity chromatography technology	Lleres D (2010)	1
POT1	2	DDX19B	2	two hybrid	Lee OH (2011)	1
CFTR	5	CLTC	12	affinity chromatography technology	Pankow S (2015)	1
CYLD	2	MVP	1	affinity chromatography technology	Elliott PR (2016)	1
LGALS3BP	5	MVP	1	affinity chromatography technology	Hein MY (2015)	1
MVP	1	MVP	1	two hybrid, two hybrid, two hybrid	Wang J (2011), Corominas R (2014), Rolland T (2014)	3
MVP	1	TCF4	26	two hybrid	Corominas R (2014)	1
UBC	7	DHX9	3	affinity chromatography technology	Matsumoto M (2005)	1
AES	2	REL	5	two hybrid	Rolland T (2014)	1
MCM2	3	HSPA8	4	affinity chromatography technology	Drissi R (2015)	1
CLTC	12	MVP	1	affinity chromatography technology	Hein MY (2015)	1
MVP	1	ZMIZ2	1	two hybrid	Corominas R (2014)	1
TRIP13	0	RBPMS	0	two hybrid	Rual JF (2005)	1
BRCA1	7	HSPA8	4	two hybrid, affinity chromatography technology	Yu X (1998), Ertych N (2016)	2
NCBP1	7	KPNA3	0	affinity chromatography technology	Hein MY (2015)	1
MVP	1	GOPC	5	affinity chromatography technology	Huttlin EL (2017)	1
ZMIZ2	1	TP53	0	two hybrid	Lee J (2007)	1
MVP	1	NOTCH2NL	1	two hybrid	Corominas R (2014)	1
PTEN	24	HSPA8	4	affinity chromatography technology, pull down	Maddika S (2011), Verrastro I (2015)	2
TRAF2	1	UBC	7	enzymatic study, enzymatic study	Liu J (2011), Kanayama A (2004)	2
MVP	1	SAXO1	1	two hybrid	Corominas R (2014)	1
NF2	1	TFCP2	1	affinity chromatography technology	Zhou L (2015)	1
MCM2	3	TGM2	2	affinity chromatography technology	Drissi R (2015)	1
LGALS3BP	5	HSP90AB1	2	affinity chromatography technology	Fogeron ML (2013)	1
TRIM27	2	TRIM42	0	two hybrid	Rolland T (2014)	1
BANP	1	C1orf94	1	two hybrid	Rolland T (2014)	1
CFTR	5	HSPA8	4	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Meacham GC (1999), Younger JM (2004), Fuller W (2000), Rubenstein RC (2000), Matsumura Y (2011), Goldstein RF (2007), Goldstein RF (2007), Meacham GC (2001), Meacham GC (2001), Wang X (2006), Matsumura Y (2013), Zaman K (2006), Pankow S (2015)	13
MVP	1	RIMBP3	0	two hybrid	Corominas R (2014)	1
RBPMS	0	BANP	1	two hybrid	Rolland T (2014)	1
U2AF2	7	HSPA8	4	affinity chromatography technology	Whisenant TC (2015)	1
SKIL	3	ESR1	0	affinity chromatography technology, pull down	Band AM (2011), Band AM (2011)	2
TGM2	2	MVP	1	affinity chromatography technology	Hein MY (2015)	1
KRAS	1	MVP	1	genetic interference	Luo J (2009)	1
KPNA2	0	KPNA3	0	biochemical	Wan C (2015)	1
BANP	1	ZMIZ2	1	two hybrid	Rolland T (2014)	1
PTEN	24	UBC	7	protein complementation assay, affinity chromatography technology	Li Y (2014), Li Y (2014)	2
TRAF2	1	CYLD	2	two hybrid, two hybrid, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kovalenko A (2003), Kovalenko A (2003), Kovalenko A (2003), Kovalenko A (2003), Yang Y (2013), Elliott PR (2016), Wu GR (2017)	7
AES	2	GOLGA2	2	two hybrid	Rolland T (2014)	1
SNW1	0	MVP	1	affinity chromatography technology	Lleres D (2010)	1
SNW1	0	NCBP1	7	affinity chromatography technology	Lleres D (2010)	1
CFTR	5	BAG3	4	affinity chromatography technology	Pankow S (2015)	1
CYLD	2	UBC	7	enzymatic study, enzymatic study, enzymatic study, pull down	Almeida S (2008), Bremm A (2010), Komander D (2009), Kwasna D (2018)	4
CDC5L	2	GOLGA2	2	two hybrid	Rolland T (2014)	1
TP53	0	UBC	7	affinity chromatography technology, affinity chromatography technology	Ayroldi E (2014), Ke JY (2014)	2
MVP	1	BANP	1	two hybrid	Corominas R (2014)	1
GOLGA2	2	TRIM42	0	two hybrid	Rolland T (2014)	1
TP53	0	CYLD	2	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Fernandez-Majada V (2016), Fernandez-Majada V (2016), Fernandez-Majada V (2016), Fernandez-Majada V (2016)	4
MCM2	3	KPNA2	0	affinity chromatography technology	Drissi R (2015)	1
TP53	0	VAT1	1	affinity chromatography technology	Fogeron ML (2013)	1
VAT1	1	MVP	1	biochemical	Kristensen AR (2012)	1
RFWD2	0	HSPA8	4	affinity chromatography technology	Yi C (2006)	1
TP53	0	CLTC	12	affinity chromatography technology	Horikawa I (2014)	1
MCM2	3	MVP	1	affinity chromatography technology	Drissi R (2015)	1
KRAS	1	PTPN1	2	genetic interference	Luo J (2009)	1
SLC2A4	1	MVP	1	affinity chromatography technology	Foster LJ (2006)	1
GOLGA2	2	SNW1	0	two hybrid	Rolland T (2014)	1
MVP	1	TFCP2	1	two hybrid	Corominas R (2014)	1
RNF111	2	SKI	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nagano Y (2007), Le Scolan E (2008), Erker Y (2013)	3
SNW1	0	CDC5L	2	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Zhang C (2003), Wan C (2015), Lleres D (2010), Lleres D (2010)	4
MVP	1	CAMK2B	9	two hybrid	Corominas R (2014)	1
MVP	1	RAB3IP	0	two hybrid	Corominas R (2014)	1
DDX19B	2	MVP	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
KCTD9	1	TRIM42	0	two hybrid	Rolland T (2014)	1
TRIM27	2	NOTCH2NL	1	two hybrid	Rolland T (2014)	1
SNW1	0	KPNA2	0	affinity chromatography technology	Lleres D (2010)	1
MVP	1	PLSCR1	0	two hybrid, two hybrid	Wang J (2011), Corominas R (2014)	2
MVP	1	PSTPIP1	3	two hybrid	Corominas R (2014)	1
TP53	0	CKAP4	0	affinity chromatography technology	Horikawa I (2014)	1
TRAF2	1	TRIM42	0	two hybrid	Rolland T (2014)	1
CFTR	5	NCBP1	7	affinity chromatography technology	Pankow S (2015)	1
MVP	1	TRIM42	0	two hybrid	Corominas R (2014)	1
SNW1	0	SKIL	3	genetic interference	Leong GM (2001)	1
SKI	3	SKIL	3	pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Cohen SB (1999), Cohen SB (1999), Tan R (2006), He J (2003), Ikeuchi Y (2014)	5
MVP	1	STN1	0	two hybrid	Corominas R (2014)	1
AES	2	RBPMS	0	two hybrid	Rolland T (2014)	1
HSP90AB1	2	MVP	1	biochemical	Kristensen AR (2012)	1
U2AF2	7	CALCOCO2	0	affinity chromatography technology	Whisenant TC (2015)	1
CYLD	2	TRIP6	2	affinity chromatography technology	Elliott PR (2016)	1
MVP	1	AES	2	two hybrid	Corominas R (2014)	1
TRIP6	2	FAM46C	3	two hybrid	Rual JF (2005)	1
RFWD2	0	MVP	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yi C (2005), Yi C (2005), Lu G (2014)	3
CDC5L	2	HSP90AB1	2	affinity chromatography technology	Lleres D (2010)	1
ESR1	0	HSP90AB1	2	affinity chromatography technology	Dhamad AE (2016)	1
CDC5L	2	MVP	1	affinity chromatography technology	Lleres D (2010)	1
BANP	1	RAB3IP	0	two hybrid	Rolland T (2014)	1
MDFI	1	PIH1D2	0	two hybrid	Rolland T (2014)	1
GTSE1	3	GOLGA2	2	affinity chromatography technology	Hein MY (2015)	1
MCM2	3	CLTC	12	affinity chromatography technology	Drissi R (2015)	1
MVP	1	TRIP6	2	two hybrid	Corominas R (2014)	1
RNF111	2	SKIL	3	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Levy L (2007), Levy L (2007), Nagano Y (2007), Erker Y (2013)	4
MVP	1	TRAF2	1	two hybrid	Corominas R (2014)	1
BAG3	4	PSAP	3	biochemical	Kristensen AR (2012)	1
BRCA1	7	PARP4	3	affinity chromatography technology	Ertych N (2016)	1
GIT2	2	MVP	1	two hybrid	Wang J (2011)	1
CYLD	2	NF2	1	affinity chromatography technology	Elliott PR (2016)	1
MVP	1	ESR1	0	affinity chromatography technology, pull down	Abbondanza C (1998), Abbondanza C (1998)	2
UBC	7	CALCOCO2	0	pull down, affinity chromatography technology, two hybrid, pull down, x-ray crystallography, pull down, affinity chromatography technology, imaging technique, pull down, imaging technique	Fenner BJ (2009), Fenner BJ (2009), Rolland T (2014), Tumbarello DA (2015), Xie X (2015), Xie X (2015), Xie X (2015), Xie X (2015), Ordureau A (2015), Minowa-Nozawa A (2017)	10
RBPMS	0	KCTD9	1	two hybrid	Rolland T (2014)	1
TP53	0	HSP90AB1	2	affinity chromatography technology	Fogeron ML (2013)	1
GTSE1	3	CLTC	12	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Hein MY (2015)	2
PTPN1	2	MVP	1	affinity chromatography technology	Hein MY (2015)	1
SNW1	0	DDX19B	2	affinity chromatography technology	Lleres D (2010)	1
AES	2	RHOXF2	0	two hybrid	Rolland T (2014)	1
BANP	1	TP53	0	pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pavithra L (2009), Pavithra L (2009), Sinha S (2010), Sinha S (2010), Sinha S (2010), Sinha S (2012), Pavithra L (2009)	7
CDC5L	2	TRIP13	0	affinity chromatography technology	Lleres D (2010)	1
RBPMS	0	RHOXF2	0	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
MVP	1	CALCOCO2	0	two hybrid	Corominas R (2014)	1
PTEN	24	HSP90AB1	2	affinity chromatography technology, pull down	Maddika S (2011), Verrastro I (2015)	2
TP53	0	NF2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TRIM27	2	KCTD9	1	two hybrid	Rolland T (2014)	1
TRIM27	2	LGALS3BP	5	affinity chromatography technology	Huttlin EL (2017)	1
CFTR	5	TGM2	2	affinity chromatography technology	Pankow S (2015)	1
SNW1	0	TRIP13	0	affinity chromatography technology	Lleres D (2010)	1
CKAP4	0	MVP	1	two hybrid	Wang J (2011)	1
MEOX2	2	TRIM42	0	two hybrid	Rolland T (2014)	1
U2AF2	7	MVP	1	affinity chromatography technology	Whisenant TC (2015)	1
PTPN1	2	STAT5B	3	unspecified method	Espanel X (2002)	1
CDC5L	2	U2AF2	7	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	David CJ (2011), David CJ (2011), Havugimana PC (2012), Lleres D (2010), Whisenant TC (2015)	5
MVP	1	RCOR3	0	affinity chromatography technology	Huttlin EL (2017)	1
SNW1	0	HSPA8	4	affinity chromatography technology	Lleres D (2010)	1
HSP90AB1	2	HSPA8	4	biochemical, affinity chromatography technology	Wan C (2015), Reidy M (2018)	2
MVP	1	MEOX2	2	two hybrid	Corominas R (2014)	1
ESR1	0	CLTC	12	affinity chromatography technology	Tarallo R (2011)	1
BRCA1	7	KPNA2	0	two hybrid, affinity chromatography technology, affinity chromatography technology	Chen CF (1996), Hill SJ (2014), Ertych N (2016)	3
KRAS	1	CYTB	0	two hybrid	Arroyo R (2015)	1
DISC1	6	CDC5L	2	two hybrid	Camargo LM (2007)	1
SKI	3	HSPA8	4	affinity chromatography technology	Rashidian J (2015)	1
MVP	1	POT1	2	two hybrid	Wang J (2011)	1
KPNA2	0	HSP90AB1	2	biochemical	Kristensen AR (2012)	1
HSPA8	4	UBC	7	two hybrid	Stelzl U (2005)	1
MVP	1	NNT	3	two hybrid	Wang J (2011)	1
EPHX2	2	MVP	1	two hybrid	Wang J (2011)	1
CFTR	5	HSP90AB1	2	affinity chromatography technology	Wang X (2006)	1
NF2	1	MVP	1	affinity chromatography technology	Zhou L (2015)	1
MVP	1	PSAP	3	biochemical	Kristensen AR (2012)	1
SKI	3	HSP90AB1	2	affinity chromatography technology	Rashidian J (2015)	1
TEP1	10	TP53	0	pull down	Li H (1999)	1
REL	5	PIH1D2	0	two hybrid	Rolland T (2014)	1
MVP	1	PIH1D2	0	two hybrid	Corominas R (2014)	1
SERTAD1	0	STAT5B	3	two hybrid	Wang J (2011)	1
HSP90AB1	2	MCM2	3	biochemical, affinity chromatography technology	Kristensen AR (2012), Drissi R (2015)	2
SIRT7	1	TP53	0	affinity chromatography technology	Tsai YC (2012)	1
TRAF2	1	RAB3IP	0	affinity chromatography technology	Huttlin EL (2017)	1
MEOX1	0	MEOX2	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
TRIM27	2	MID2	1	two hybrid	Rolland T (2014)	1
MCM2	3	LGALS3BP	5	affinity chromatography technology	Drissi R (2015)	1
MCM2	3	DHX9	3	affinity chromatography technology	Drissi R (2015)	1
PARP4	3	TEP1	10	affinity chromatography technology	Liu Y (2004)	1
TRIM42	0	CCDC36	1	two hybrid	Rolland T (2014)	1
MVP	1	TEP1	10	biochemical, affinity chromatography technology	Kickhoefer VA (1999), Kickhoefer VA (1999)	2
SERTAD1	0	TGM2	2	two hybrid	Wang J (2011)	1
MVP	1	VAC14	5	two hybrid	Corominas R (2014)	1
AES	2	U2AF2	7	two hybrid	Rolland T (2014)	1
CFTR	5	TP53	0	affinity chromatography technology	Pankow S (2015)	1
HSPA8	4	BAG3	4	two hybrid, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Takayama S (1999), Takayama S (1999), Takayama S (1999), Gentilella A (2011), Hishiya A (2011), Chen Y (2013), Chen Y (2013), Taipale M (2014), Taipale M (2014), Rolland T (2014), Hein MY (2015)	11
MID2	1	BRCA1	7	two hybrid	Hill SJ (2014)	1
U2AF2	7	DHX9	3	affinity chromatography technology	Whisenant TC (2015)	1
CYLD	2	HSPA8	4	affinity chromatography technology	Elliott PR (2016)	1
MVP	1	ADAMTSL4	6	two hybrid	Corominas R (2014)	1
MVP	1	HSPA8	4	affinity chromatography technology	Huttlin EL (2017)	1
TSPOAP1	9	DLX2	0	two hybrid	Corominas R (2014)	1
BRCA1	7	KPNA3	0	affinity chromatography technology	Ertych N (2016)	1
MVP	1	MEOX1	0	two hybrid	Corominas R (2014)	1
MVP	1	FAM46C	3	two hybrid	Corominas R (2014)	1
CYLD	2	CDC5L	2	affinity chromatography technology	Elliott PR (2016)	1
NCBP1	7	MVP	1	biochemical	Kristensen AR (2012)	1
MVP	1	SKIL	3	two hybrid	Corominas R (2014)	1
CYTB	0	MVP	1	two hybrid	Wang J (2011)	1
UBC	7	MVP	1	pull down	Zhang X (2017)	1
GOLGA2	2	RCOR3	0	two hybrid	Rolland T (2014)	1
TP53	0	HSPA8	4	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Akakura S (2001), Kaur J (1996), Fogeron ML (2013), Horikawa I (2014), Matsumoto H (1994), Matsumoto H (1994), Karras GI (2017)	7
MVP	1	TSPOAP1	9	two hybrid	Corominas R (2014)	1
MVP	1	GOLGA2	2	two hybrid	Corominas R (2014)	1
BRCA1	7	MCM2	3	affinity chromatography technology	Ertych N (2016)	1
TCF4	26	GOPC	5	affinity chromatography technology	Li X (2015)	1
TSPOAP1	9	TCF4	26	two hybrid	Corominas R (2014)	1
TP53	0	TGM2	2	affinity chromatography technology, affinity chromatography technology	Kang JH (2016), Kang JH (2016)	2
BRCA1	7	LGALS3BP	5	affinity chromatography technology	Ertych N (2016)	1
PTPN1	2	TRIP13	0	affinity chromatography technology	Li X (2016)	1
NCBP1	7	KPNA2	0	affinity chromatography technology	Hein MY (2015)	1
TRAF2	1	BANP	1	two hybrid, two hybrid	Rual JF (2005), Rolland T (2014)	2
HSPA8	4	TGM2	2	two hybrid	Wang J (2011)	1
SIRT7	1	SNW1	0	affinity chromatography technology	Tsai YC (2012)	1
CYLD	2	CLTC	12	affinity chromatography technology	Elliott PR (2016)	1
FAM46C	3	RHOXF2	0	two hybrid	Rolland T (2014)	1
LGALS3BP	5	HSPA8	4	affinity chromatography technology	Fogeron ML (2013)	1
U2AF2	7	HSP90AB1	2	affinity chromatography technology	Whisenant TC (2015)	1
MVP	1	MID2	1	two hybrid	Corominas R (2014)	1
CFTR	5	GOPC	5	two hybrid, pull down, affinity chromatography technology	Cheng J (2002), Gentzsch M (2003), Cheng J (2002)	3
CFTR	5	MCM2	3	affinity chromatography technology	Pankow S (2015)	1
MCM2	3	CKAP4	0	affinity chromatography technology	Drissi R (2015)	1
CHMP4B	2	MVP	1	biochemical	Havugimana PC (2012)	1
RCOR3	0	TRIM42	0	two hybrid	Rolland T (2014)	1
TRIM27	2	RCOR3	0	two hybrid	Rolland T (2014)	1
MVP	1	KPNA3	0	two hybrid	Corominas R (2014)	1
SIRT7	1	NNT	3	affinity chromatography technology	Tsai YC (2012)	1
RNF111	2	UBC	7	enzymatic study	Wright JD (2016)	1
ADAMTSL4	6	TRIM42	0	two hybrid	Rolland T (2014)	1
MVP	1	ZBTB32	0	two hybrid	Corominas R (2014)	1
HSP90AB1	2	TRAF2	1	imaging technique	Chen TC (2014)	1
POT1	2	HSP90AB1	2	two hybrid	Lee OH (2011)	1
SNW1	0	SKI	3	two hybrid, pull down, two hybrid, pull down, affinity chromatography technology, genetic interference	Prathapam T (2001), Prathapam T (2001), Dahl R (1998), Dahl R (1998), Dahl R (1998), Leong GM (2001)	6
BRCA1	7	PSAP	3	two hybrid	Woods NT (2012)	1
PTPN1	2	RFWD2	0	affinity chromatography technology, affinity chromatography technology, pull down	Ren W (2013), Ren W (2013), Ren W (2013)	3
ESR1	0	GOLGA2	2	affinity chromatography technology	Tarallo R (2011)	1
3240	0	TGM2	2	two hybrid	Wang J (2011)	1
MID2	1	TRIM42	0	two hybrid	Rolland T (2014)	1
SIRT7	1	MVP	1	affinity chromatography technology	Tsai YC (2012)	1
BAG3	4	MVP	1	biochemical	Kristensen AR (2012)	1
TRIP6	2	ADAMTSL4	6	two hybrid	Rolland T (2014)	1
TP53	0	ESR1	0	pull down, affinity chromatography technology, affinity chromatography technology	Liu G (2000), Duong V (2007), Saxena R (2016)	3
TP53	0	TCF4	26	pull down, affinity chromatography technology	Kotlyar M (2015), Li X (2015)	2
MCM2	3	UBC	7	affinity chromatography technology	Drissi R (2015)	1
MVP	1	KCTD9	1	two hybrid	Corominas R (2014)	1
AES	2	CALCOCO2	0	two hybrid	Rolland T (2014)	1
MVP	1	C1orf94	1	two hybrid	Corominas R (2014)	1
UBC	7	HSP90AB1	2	affinity chromatography technology	Bish RA (2007)	1
SNW1	0	HSP90AB1	2	affinity chromatography technology	Lleres D (2010)	1
CFTR	5	PSAP	3	affinity chromatography technology	Wang X (2006)	1
AES	2	C1orf94	1	two hybrid	Rolland T (2014)	1
KRAS	1	RBPMS	0	two hybrid	Rolland T (2014)	1
C1orf94	1	HSPA8	4	affinity chromatography technology	Huttlin EL (2017)	1
PTEN	24	ESR1	0	pull down	Lin HK (2004)	1
CYLD	2	HSP90AB1	2	affinity chromatography technology	Elliott PR (2016)	1
ESR1	0	U2AF2	7	affinity chromatography technology	Tarallo R (2011)	1
ESR1	0	HSPA8	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Fan M (2005), Tateishi Y (2004), Ambrosino C (2010), Tarallo R (2011), Gebauer M (1998), Dhamad AE (2016), Dhamad AE (2016)	7
AES	2	SKIL	3	two hybrid	Rolland T (2014)	1
POT1	2	SERTAD1	0	two hybrid	Wang J (2011)	1
RFWD2	0	PARP4	3	affinity chromatography technology	Lu G (2014)	1
NF2	1	KPNA2	0	affinity chromatography technology	Zhou L (2015)	1
MVP	1	TP53	0	two hybrid	Corominas R (2014)	1
UBC	7	DDX19B	2	pull down	Zhang X (2017)	1
BRCA1	7	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, biochemical, pull down, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Abramovitch S (2004), Ouchi T (1998), Dong Y (2003), Dong Y (2003), Chai YL (1999), Chai YL (1999), Zhang H (1998), Dong Y (2003), Chen Y (2006), Quaresima B (2006), Zhang H (1998), Zhang H (1998), Mark WY (2005), Jin S (2009), Jiang J (2011), Rasti M (2015), Rasti M (2015)	17
NCBP1	7	VAT1	1	biochemical	Kristensen AR (2012)	1
MVP	1	RNF111	2	two hybrid	Corominas R (2014)	1
UBC	7	BRCA1	7	pull down, enzymatic study	Sobhian B (2007), Zhao GY (2007)	2
3240	0	MVP	1	two hybrid	Wang J (2011)	1
MVP	1	RBPMS	0	two hybrid	Corominas R (2014)	1
MVP	1	MKL1	2	two hybrid	Corominas R (2014)	1
MID2	1	RCOR3	0	two hybrid	Rolland T (2014)	1
CDC5L	2	HSPA8	4	affinity chromatography technology, biochemical, affinity chromatography technology	Ajuh P (2000), Ajuh P (2000), Lleres D (2010)	3
MCM2	3	U2AF2	7	affinity chromatography technology	Drissi R (2015)	1
CALCOCO2	0	MID2	1	two hybrid	Rolland T (2014)	1
SIRT7	1	U2AF2	7	affinity chromatography technology	Tsai YC (2012)	1
SKI	3	ESR1	0	affinity chromatography technology	Band AM (2011)	1
ZBTB32	0	RHOXF2	0	two hybrid, two hybrid, two hybrid	Rual JF (2005), Xin X (2009), Rolland T (2014)	3
DHX9	3	MVP	1	biochemical	Havugimana PC (2012)	1
SIRT7	1	CLTC	12	affinity chromatography technology	Tsai YC (2012)	1
KPNA2	0	MDFI	1	two hybrid	Rolland T (2014)	1
PLSCR1	0	TRIM42	0	two hybrid	Rolland T (2014)	1
NF2	1	CHMP4B	2	affinity chromatography technology	Zhou L (2015)	1
TSPOAP1	9	REL	5	two hybrid	Corominas R (2014)	1
MVP	1	CCDC36	1	two hybrid	Corominas R (2014)	1
MVP	1	RHOXF2	0	two hybrid	Corominas R (2014)	1
TRIM27	2	TP53	0	affinity chromatography technology, pull down, enzymatic study	Chu Y (2011), Chu Y (2011), Chu Y (2011)	3
MVP	1	TRIP13	0	two hybrid	Corominas R (2014)	1
MVP	1	MDFI	1	two hybrid	Corominas R (2014)	1
DDX19B	2	3240	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MVP	1	DLX2	0	two hybrid	Corominas R (2014)	1
CFTR	5	LGALS3BP	5	affinity chromatography technology	Pankow S (2015)	1
RFWD2	0	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dornan D (2006), Dornan D (2004), Dornan D (2004), Dornan D (2004), Dornan D (2004), Choi HH (2011), Yamada T (2013), Zou S (2016)	8
STAT5B	3	MVP	1	affinity chromatography technology	Hein MY (2015)	1
RBPMS	0	ZBTB32	0	two hybrid	Rolland T (2014)	1
TRIP6	2	SAXO1	1	two hybrid	Rolland T (2014)	1
KPNA2	0	RBPMS	0	two hybrid	Rolland T (2014)	1
AES	2	TRIM27	2	two hybrid	Rolland T (2014)	1
MVP	1	DISC1	6	two hybrid	Corominas R (2014)	1
CYLD	2	DHX9	3	affinity chromatography technology	Elliott PR (2016)	1
U2AF2	7	CLTC	12	affinity chromatography technology	Whisenant TC (2015)	1
MVP	1	SERTAD1	0	two hybrid	Corominas R (2014)	1
PLSCR1	0	ADAMTSL4	6	two hybrid	Rual JF (2005)	1
SKI	3	MVP	1	affinity chromatography technology	Rashidian J (2015)	1
TP53	0	CHMP4B	2	affinity chromatography technology	Horikawa I (2014)	1
BRCA1	7	ESR1	0	imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Zheng L (2001), Fan S (2001), Fan S (2001), Kawai H (2002), Fan S (2002), Fan S (2002), Nakuci E (2006), Wang C (2005), Wang C (2005), Dizin E (2010), Dizin E (2010), Ma Y (2010), Ma Y (2010), Fan S (2001), Ma YX (2005), Ma YX (2005), Ma YX (2005), Ma Y (2007), Ma Y (2007), Kawai H (2002), Jung YS (2014), Kawai H (2002), Kawai H (2002)	23
BRCA1	7	MVP	1	affinity chromatography technology	Ertych N (2016)	1
AES	2	NOTCH2NL	1	two hybrid	Rolland T (2014)	1
SNW1	0	U2AF2	7	affinity chromatography technology, affinity chromatography technology	Lleres D (2010), Whisenant TC (2015)	2
CFTR	5	KPNA2	0	affinity chromatography technology	Pankow S (2015)	1
CDC5L	2	DHX9	3	biochemical	Wan C (2015)	1
GOLGA2	2	MID2	1	two hybrid	Rolland T (2014)	1
CDC5L	2	KPNA2	0	affinity chromatography technology	Lleres D (2010)	1
DHX9	3	BRCA1	7	affinity chromatography technology, pull down, two hybrid, affinity chromatography technology	Schlegel BP (2003), Anderson SF (1998), Anderson SF (1998), Ertych N (2016)	4
SNW1	0	DHX9	3	affinity chromatography technology	Lleres D (2010)	1
MID2	1	ADAMTSL4	6	two hybrid	Rolland T (2014)	1
PARP4	3	MVP	1	two hybrid, two hybrid, pull down, affinity chromatography technology	van Zon A (2002), Kickhoefer VA (1999), Kickhoefer VA (1999), Huttlin EL (2017)	4
TRAF2	1	CALCOCO2	0	two hybrid	Rual JF (2005)	1
TP53	0	SNW1	0	affinity chromatography technology	Fogeron ML (2013)	1
TRIM42	0	NOTCH2NL	1	two hybrid	Rolland T (2014)	1
TRAF2	1	RCOR3	0	two hybrid, two hybrid	Rolland T (2014), Yu H (2011)	2
BAG3	4	HSP90AB1	2	affinity chromatography technology, biochemical	Chen Y (2013), Kristensen AR (2012)	2
MVP	1	REL	5	two hybrid	Corominas R (2014)	1
KRAS	1	MDFI	1	two hybrid	Rolland T (2014)	1
VAC14	5	RHOXF2	0	two hybrid	Rolland T (2014)	1
PTEN	24	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Freeman DJ (2003), Freeman DJ (2003), Zhou M (2003), Zhou M (2003), Hong SW (2013), Li Y (2008)	6
KPNA2	0	MVP	1	two hybrid	Wang J (2011)	1
CDC5L	2	PARP4	3	affinity chromatography technology	Lleres D (2010)	1
U2AF2	7	NCBP1	7	affinity chromatography technology	Whisenant TC (2015)	1
KRAS	1	SNW1	0	genetic interference	Luo J (2009)	1
POT1	2	BAG3	4	two hybrid	Lee OH (2011)	1
BRCA1	7	CLTC	12	affinity chromatography technology	Ertych N (2016)	1
UBC	7	TRIM27	2	affinity chromatography technology	Matsumoto M (2005)	1
CALCOCO2	0	GIT2	2	two hybrid	Wang J (2011)	1
CLTC	12	PARP4	3	affinity chromatography technology	Hein MY (2015)	1
AES	2	TCF4	26	two hybrid	Rolland T (2014)	1
SIRT7	1	NCBP1	7	affinity chromatography technology	Tsai YC (2012)	1
AES	2	RIMBP3	0	two hybrid	Rolland T (2014)	1
CFTR	5	MVP	1	affinity chromatography technology	Pankow S (2015)	1
TSPOAP1	9	DISC1	6	two hybrid	Corominas R (2014)	1
PTEN	24	MVP	1	two hybrid, affinity chromatography technology, pull down	Yu Z (2002), Yu Z (2002), Yu Z (2002)	3
SKI	3	TP53	0	affinity chromatography technology	Inoue Y (2011)	1
GTSE1	3	MVP	1	affinity chromatography technology	Hein MY (2015)	1
BRCA1	7	CDC5L	2	affinity chromatography technology	Ertych N (2016)	1
CAMK2B	9	RBPMS	0	two hybrid	Rolland T (2014)	1
ESR1	0	DHX9	3	affinity chromatography technology, pull down	Tarallo R (2011), Nalvarte I (2010)	2
RHOXF2	0	TRIP13	0	two hybrid, two hybrid	Venkatesan K (2009), Rolland T (2014)	2
CLTC	12	CHMP4B	2	affinity chromatography technology	Hein MY (2015)	1
BRCA1	7	HSP90AB1	2	affinity chromatography technology	Ertych N (2016)	1
AES	2	TRAF2	1	two hybrid	Rolland T (2014)	1
MVP	1	TRIM27	2	two hybrid	Corominas R (2014)	1