PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
RELA	1	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TP53	0	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Wang C (2003), Akakura S (2001), Peng Y (2001), Nagata Y (1999), Wang J (2011), Burch L (2004), Taipale M (2012), Fogeron ML (2013), Walerych D (2004)	9
MAP2K1	8	BLM	2	genetic interference	Srivas R (2016)	1
BRCA1	7	VEGFA	3	genetic interference	Shen JP (2017)	1
CDC5L	2	PRKDC	12	affinity chromatography technology, biochemical, affinity chromatography technology	Ajuh P (2000), Ajuh P (2000), Lleres D (2010)	3
BRD4	8	ATAD5	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rahman S (2011), Rahman S (2011), Rahman S (2011), Rahman S (2011)	4
MSH2	4	ATM	9	biochemical	Wang Y (2000)	1
MET	7	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MDM4	0	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, pull down, pull down, biochemical, affinity chromatography technology, affinity chromatography technology	Jin Y (2008), Jin Y (2008), Jin Y (2008), Jin Y (2008), Jin Y (2008), Lee JH (2011), Lee JH (2011)	7
PCNA	0	DNMT1	5	affinity chromatography technology, pull down, pull down, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rountree MR (2000), Iida T (2002), Chuang LS (1997), Ha K (2011), Pichler G (2012), Pichler G (2012), Pichler G (2012), Hervouet E (2010), Hervouet E (2010), Cai Y (2014), Han J (2014), Hein MY (2015)	12
COPS5	0	FEM1B	1	affinity chromatography technology	Bennett EJ (2010)	1
MSH6	2	TOPBP1	5	affinity chromatography technology, affinity chromatography technology	Liu Y (2010), Liu Y (2010)	2
USP7	14	CLSPN	1	affinity chromatography technology, enzymatic study	Faustrup H (2009), Faustrup H (2009)	2
USP7	14	DNMT1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, pull down, x-ray crystallography, affinity chromatography technology, enzymatic study	Sowa ME (2009), Felle M (2011), Felle M (2011), Felle M (2011), Felle M (2011), Felle M (2011), Qin W (2011), Qin W (2011), Du Z (2010), Du Z (2010), Du Z (2010), Du Z (2010), Ma H (2012), Hein MY (2015), Cheng J (2015), Cheng J (2015), Cheng J (2015), Cheng J (2015), Cheng J (2015)	19
CUL1	7	USP11	3	affinity chromatography technology	Bennett EJ (2010)	1
23380	0	KIF13B	13	affinity chromatography technology	Boldt K (2016)	1
MCPH1	4	TP53BP1	3	imaging technique	Rai R (2006)	1
PTEN	24	CASP8	1	affinity chromatography technology, affinity chromatography technology	Crockett DK (2005), Crockett DK (2005)	2
BRCA1	7	RB1	2	affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, pull down, pull down, affinity chromatography technology, genetic interference	Aprelikova ON (1999), Fan S (2001), Fan S (2001), Fan S (2001), Yarden RI (1999), Aprelikova ON (1999), Aprelikova ON (1999), Shen JP (2017)	8
COPS5	0	UBA1	1	affinity chromatography technology	Bennett EJ (2010)	1
HSP90AA1	7	WEE1	2	genetic interference	Shen JP (2017)	1
CDC25C	0	23380	0	affinity chromatography technology	Boldt K (2016)	1
LDLRAP1	0	CHEK1	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PRKDC	12	CHEK2	2	enzymatic study	Chan DW (2000)	1
CHEK2	2	APP	1	pull down	Olah J (2011)	1
CDK9	3	CDC73	1	affinity chromatography technology	Jeronimo C (2007)	1
ATXN3	2	CHEK1	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study	Tu Y (2017), Tu Y (2017), Tu Y (2017), Tu Y (2017), Tu Y (2017)	5
FZR1	1	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
SNX11	3	CHEK1	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PRKDC	12	ATM	9	unspecified method, affinity chromatography technology, affinity chromatography technology	Kim ST (1999), Suzuki K (1999), Suzuki K (1999)	3
CDC5L	2	SMARCA4	19	affinity chromatography technology	Lleres D (2010)	1
HSP90AA1	7	VCP	6	affinity chromatography technology, affinity chromatography technology	Vij N (2006), Yu CC (2013)	2
CDC14A	4	CDC6	0	enzymatic study	Bremmer SC (2012)	1
RELA	1	TP53	0	affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Huang WC (2007), Huang WC (2007), Ivanov AA (2017)	3
TOP2A	2	VHL	0	affinity chromatography technology	Yun J (2009)	1
CASP8	1	BCL2L1	0	genetic interference	Guo Y (2002)	1
ATXN3	2	TP53	0	affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study	Liu H (2016), Liu H (2016), Liu H (2016), Liu H (2016), Liu H (2016)	5
CDK9	3	ATR	6	affinity chromatography technology	Yu DS (2010)	1
XRCC5	5	TOP2A	2	affinity chromatography technology	Matheos D (2002)	1
CUL1	7	RACGAP1	2	affinity chromatography technology	Bennett EJ (2010)	1
CHEK2	2	CHEK1	2	genetic interference	Srivas R (2016)	1
MSH2	4	CHEK2	2	affinity chromatography technology, pull down, affinity chromatography technology	Adamson AW (2005), Brown KD (2003), Brown KD (2003)	3
DENND1A	2	KIF13B	13	affinity chromatography technology	Boldt K (2016)	1
CDK1	0	HSP90AA1	7	affinity chromatography technology	Garcia-Morales P (2007)	1
CSNK2A1	15	PRKDC	12	affinity chromatography technology, imaging technique, affinity chromatography technology	Olsen BB (2012), Olsen BB (2012), Olsen BB (2012)	3
KSR1	0	ZBTB21	2	affinity chromatography technology	Boldt K (2016)	1
ATR	6	WRN	6	unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kim ST (1999), Otterlei M (2006), Patro BS (2011), Patro BS (2011)	4
UNC5CL	5	CHEK1	2	affinity chromatography technology	Huttlin EL (2017)	1
BRCA1	7	XIAP	0	affinity chromatography technology, pull down	Martin SA (2005), Martin SA (2005)	2
XPO1	8	KSR1	0	affinity chromatography technology	Kirli K (2015)	1
CHEK2	2	CUL1	7	affinity chromatography technology	Huh J (2013)	1
TUBA1A	13	ATAD5	5	genetic interference	Srivas R (2016)	1
AKT1	1	DNMT1	5	enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down	Esteve PO (2011), Esteve PO (2011), Esteve PO (2011), Esteve PO (2011)	4
CASP8	1	RB1	2	enzymatic study	Lemaire C (2005)	1
VCP	6	CHEK1	2	affinity chromatography technology	Yu CC (2013)	1
BRCA1	7	BLM	2	biochemical, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Acharya S (2014), Ertych N (2016)	3
CHEK2	2	RPS10	0	genetic interference	Srivas R (2016)	1
MTOR	14	PRKDC	12	genetic interference	Shen JP (2017)	1
FBXO6	0	PCNA	0	affinity chromatography technology	Liu B (2012)	1
ATR	6	DTL	0	enzymatic study	Sakaguchi H (2012)	1
MCPH1	4	NBN	1	imaging technique	Rai R (2006)	1
CDC25C	0	CDK1	0	pull down, affinity chromatography technology	Morris MC (2000), St-Denis N (2016)	2
SH3PXD2A	4	KIF13B	13	affinity chromatography technology	Boldt K (2016)	1
ARID1A	16	TOP1	1	genetic interference	Shen JP (2017)	1
VAV1	2	CHEK1	2	affinity chromatography technology	Huttlin EL (2017)	1
CUL4A	2	TP53	0	affinity chromatography technology	Banks D (2006)	1
FBXO6	0	COPS5	0	affinity chromatography technology	Liu B (2012)	1
CASP8	1	IL13RA2	0	two hybrid	Arroyo R (2015)	1
HSP90AA1	7	ATR	6	affinity chromatography technology, affinity chromatography technology, genetic interference	Ha K (2011), Ha K (2011), Srivas R (2016)	3
SRC	2	CDC25A	2	enzymatic study	Liang J (2016)	1
MAP2K1	8	TUSC3	1	genetic interference	Srivas R (2016)	1
USP7	14	RB1	2	affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Bhattacharya S (2014), Bhattacharya S (2014), Bhattacharya S (2014), Bhattacharya S (2014)	4
CDC25A	2	XPO1	8	two hybrid	Wang J (2011)	1
CUL1	7	RPS10	0	affinity chromatography technology	Bennett EJ (2010)	1
TP53	0	CDC14A	4	two hybrid, affinity chromatography technology, pull down	Li L (2000), Li L (2000), Li L (2000)	3
IGF1R	5	ILKAP	2	two hybrid	Yao Z (2017)	1
FZR1	1	CDC25A	2	affinity chromatography technology, pull down, enzymatic study	Gao D (2009), Donzelli M (2002), Donzelli M (2002)	3
VHL	0	CHEK2	2	affinity chromatography technology, enzymatic study	Roe JS (2011), Roe JS (2011)	2
HSP90AA1	7	PRKDC	12	affinity chromatography technology	Falsone SF (2005)	1
PRKDC	12	WRN	6	unspecified method, affinity chromatography technology, enzymatic study	Kim ST (1999), Karmakar P (2002), Karmakar P (2002)	3
CDK9	3	CHEK1	2	genetic interference	Shen JP (2017)	1
PARP1	3	XRCC5	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, enzymatic study, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Ju BG (2006), Galande S (1999), Galande S (1999), Galande S (1999), Idogawa M (2007), Li B (2004), Li B (2004), Yin H (2006), Yin H (2006), Sand-Dejmek J (2011), Wu T (2013)	11
BLM	2	WRN	6	affinity chromatography technology, pull down	von Kobbe C (2002), von Kobbe C (2002)	2
CHEK1	2	XRCC5	5	affinity chromatography technology	Goudelock DM (2003)	1
AKT1	1	TOPBP1	5	enzymatic study, affinity chromatography technology	Liu K (2006), Liu K (2006)	2
NFATC1	12	XRCC6	3	affinity chromatography technology	Gabriel CH (2016)	1
TCEAL1	3	DTL	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CHEK1	2	RELA	1	enzymatic study	Rocha S (2005)	1
PCNA	0	FANCE	6	affinity chromatography technology	Geng L (2010)	1
SNW1	0	XRCC6	3	affinity chromatography technology	Lleres D (2010)	1
ARID1A	16	VHL	0	genetic interference	Shen JP (2017)	1
FZR1	1	NEK2	2	affinity chromatography technology, affinity chromatography technology, enzymatic study	Sedgwick GG (2012), Boekhout M (2015), Lee SB (2015)	3
MTOR	14	PTEN	24	genetic interference	Shen JP (2017)	1
XPO1	8	CDC73	1	affinity chromatography technology	Kirli K (2015)	1
HSP90AA1	7	UBA1	1	affinity chromatography technology	Falsone SF (2005)	1
RAD23A	1	XRCC5	5	affinity chromatography technology	Scanlon TC (2009)	1
FBXO6	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yoshida Y (2007), Nelson RF (2007), Glenn KA (2008), Yoshida Y (2011), Liu B (2012), Liu B (2012), Huttlin EL (2015), Huttlin EL (2017), Reitsma JM (2017), Reitsma JM (2017)	10
RFC1	1	RACGAP1	2	biochemical	Wan C (2015)	1
CHEK1	2	DENND1A	2	affinity chromatography technology	Boldt K (2016)	1
XRCC6	3	IMPDH1	2	biochemical	Kristensen AR (2012)	1
TP53BP1	3	COPS5	0	two hybrid, affinity chromatography technology	Kwak HJ (2005), Kwak HJ (2005)	2
CHEK1	2	MED15	6	biochemical	Havugimana PC (2012)	1
BRCA1	7	TOPBP1	5	affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Greenberg RA (2006), Mok MT (2010), Tian F (2013), Hill SJ (2014), Sakasai R (2012)	5
ATR	6	NBN	1	unspecified method, pull down, affinity chromatography technology	Kim ST (1999), Falck J (2005), Falck J (2005)	3
ATXN3	2	DDB1	6	affinity chromatography technology, affinity chromatography technology	Tu Y (2017), Tu Y (2017)	2
CDC25C	0	MAPK1	1	affinity chromatography technology, pull down	Eymin B (2006), Eymin B (2006)	2
ILKAP	2	CHEK1	2	enzymatic study	Zhang X (2017)	1
CHEK2	2	TP53	0	affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Louria-Hayon I (2003), Shieh SY (2000), Bjorling-Poulsen M (2005), Hirao A (2000), Adams CJ (2008)	5
AKT1	1	SFN	1	affinity chromatography technology, affinity chromatography technology	Calvo N (2010), Calvo N (2010)	2
CBY1	3	GIGYF1	15	affinity chromatography technology	Boldt K (2016)	1
HLA-DRB5	4	HSP90AA1	7	affinity chromatography technology	Buschow SI (2010)	1
L3HYPDH	3	CHEK1	2	affinity chromatography technology	Huttlin EL (2015)	1
CDC73	1	PRKDC	12	affinity chromatography technology	Herr P (2015)	1
CHEK1	2	LRFN1	4	affinity chromatography technology	Boldt K (2016)	1
HSP90AA1	7	BRCA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Johnson N (2013), Johnson N (2013), Ertych N (2016)	3
SMARCA4	19	SMARCC1	5	biochemical, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical	Sif S (2001), Wang W (1996), Otsuki T (2001), Zhao K (1998), Kaeser MD (2008), Kaeser MD (2008), Kaeser MD (2008), Kaeser MD (2008), Inayoshi Y (2006), Inayoshi Y (2006), Pal S (2003), Pal S (2003), Bultman SJ (2005), Nagl NG (2005), Mahajan MC (2005), Trotter KW (2008), Dallas PB (1998), Tando T (2010), Tando T (2010), Bartlett C (2011), Bartlett C (2011), Oh J (2008), Oh J (2008), Havugimana PC (2012), Wan C (2015)	25
RAD23A	1	CHEK1	2	affinity chromatography technology, affinity chromatography technology, pull down	Tan X (2015), Tan X (2015), Tan X (2015)	3
CSNK2A1	15	CDC25B	4	enzymatic study, pull down, affinity chromatography technology	Theis-Febvre N (2003), Theis-Febvre N (2003), Theis-Febvre N (2003)	3
BRD4	8	MAP2K1	8	genetic interference	Shen JP (2017)	1
KSR1	0	MAP2K1	8	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chen C (2008), Harrison RE (2004), Gloeckner CJ (2007), Hein MY (2015)	4
NFATC2	1	XRCC6	3	affinity chromatography technology	Gabriel CH (2016)	1
BRCA1	7	BRD4	8	genetic interference	Shen JP (2017)	1
PCNA	0	CHEK1	2	affinity chromatography technology	Scorah J (2008)	1
VAV1	2	RACGAP1	2	pull down	Das B (2000)	1
FZR1	1	DDB1	6	affinity chromatography technology, affinity chromatography technology	Lv XB (2010), Lv XB (2010)	2
ZBTB21	2	GIGYF1	15	affinity chromatography technology	Boldt K (2016)	1
TP53	0	EIF4E2	2	affinity chromatography technology	Fogeron ML (2013)	1
CDC5L	2	BRD4	8	affinity chromatography technology	Lleres D (2010)	1
CUL4A	2	DTL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Higa LA (2006), Bennett EJ (2010), Sertic S (2013), Rossi M (2013), Jin J (2006), Shibata E (2011), Higa LA (2006)	7
XRCC5	5	TOP1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Sand-Dejmek J (2011), Ando K (2017), Ando K (2017), Ando K (2017), Ando K (2017)	5
TUBA1A	13	BLM	2	genetic interference	Srivas R (2016)	1
NFATC2	1	TLK1	5	affinity chromatography technology	Gabriel CH (2016)	1
TOP3A	0	TTN	102	genetic interference	Srivas R (2016)	1
VHL	0	XRCC5	5	affinity chromatography technology	Lai Y (2011)	1
HSP90AA1	7	APP	1	affinity chromatography technology	Kumar P (2007)	1
ATM	9	CHEK1	2	unspecified method, enzymatic study, genetic interference	Kim ST (1999), Sorensen CS (2003), Shen JP (2017)	3
WEE1	2	KCTD3	2	affinity chromatography technology	Boldt K (2016)	1
USP11	3	USP7	14	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Sowa ME (2009), Sowa ME (2009), Maertens GN (2010), Maertens GN (2010), Ma H (2012), Hein MY (2015)	7
VHL	0	APP	1	pull down	Olah J (2011)	1
TP53	0	DNMT1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Palii SS (2008), Zhang H (2013), Zhang H (2013)	3
KSR1	0	DENND1A	2	affinity chromatography technology	Boldt K (2016)	1
KSR1	0	SH3PXD2A	4	affinity chromatography technology	Boldt K (2016)	1
FANCD2	3	RAD51	3	affinity chromatography technology, biochemical, imaging technique, pull down	Chen X (2016), Chen X (2016), Sato K (2016), Sato K (2016)	4
MDM4	0	USP7	14	pull down, x-ray crystallography, unspecified method	Sarkari F (2010), Sarkari F (2010), Sarkari F (2010)	3
CDC73	1	CUL1	7	affinity chromatography technology	Herr P (2015)	1
BRCA1	7	RELA	1	pull down, affinity chromatography technology, pull down, affinity chromatography technology	Benezra M (2003), Benezra M (2003), Benezra M (2003), Volcic M (2012)	4
CSNK2A1	15	COPS5	0	affinity chromatography technology	Bhansali M (2014)	1
FANCD2	3	BRCA1	7	two hybrid, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Reuter TY (2003), Vandenberg CJ (2003), Garcia-Higuera I (2001), Garcia-Higuera I (2001), Loke J (2015)	5
UBA1	1	CHEK1	2	pull down	Tan X (2015)	1
DENND1A	2	CBY1	3	affinity chromatography technology	Boldt K (2016)	1
HSP90AA1	7	FZR1	1	genetic interference	Srivas R (2016)	1
EIF4E2	2	DENND1A	2	affinity chromatography technology	Boldt K (2016)	1
CDC25B	4	CDK1	0	affinity chromatography technology, affinity chromatography technology	Vincent I (2001), Zhong Y (2017)	2
CDC5L	2	CHEK1	2	affinity chromatography technology	Lleres D (2010)	1
XPO1	8	RPS10	0	affinity chromatography technology	Kirli K (2015)	1
SNW1	0	CDC5L	2	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Zhang C (2003), Wan C (2015), Lleres D (2010), Lleres D (2010)	4
BRCA1	7	TARS	2	two hybrid, affinity chromatography technology	Woods NT (2012), Ertych N (2016)	2
ZBTB21	2	KIF13B	13	affinity chromatography technology	Boldt K (2016)	1
XIAP	0	AKT1	1	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, imaging technique	Dan HC (2004), Dan HC (2004), Pramanik KC (2013), Pramanik KC (2013), Chen TC (2014)	5
VEGFA	3	VHL	0	genetic interference	Shen JP (2017)	1
KSR1	0	CDC25C	0	affinity chromatography technology	Boldt K (2016)	1
BCL2L14	2	VHL	0	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
VHL	0	TARS	2	affinity chromatography technology	Ewing RM (2007)	1
TOP1	1	WEE1	2	genetic interference	Srivas R (2016)	1
BCL2L14	2	BCL2L1	0	affinity chromatography technology	Guo B (2001)	1
TP53	0	SMARCC1	5	biochemical, affinity chromatography technology	Lee D (2002), Oh J (2008)	2
CDC25C	0	ZBTB21	2	affinity chromatography technology	Boldt K (2016)	1
TUBA1A	13	CHEK2	2	genetic interference	Srivas R (2016)	1
COPS5	0	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Min KW (2005), Min KW (2005), Chua YS (2011), Boh BK (2011), Emberley ED (2012), Emberley ED (2012), Choo YY (2011), Choo YY (2011), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012), Enchev RI (2012), Birol M (2014), Pick E (2012), Sharon M (2009), Enchev RI (2012), Bornstein G (2015), Rockel B (2014), Schlierf A (2016), Reitsma JM (2017), Reitsma JM (2017)	23
TOPBP1	5	BLM	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, pull down	Wang J (2013), Wang J (2013), Wang J (2013), Wang J (2013), Wang J (2013), Wang J (2013), Wang J (2013)	7
CHEK1	2	FZR1	1	genetic interference	Srivas R (2016)	1
ZEB1	3	SMARCA4	19	affinity chromatography technology, affinity chromatography technology	Sanchez-Tillo E (2010), Sanchez-Tillo E (2010)	2
ADA	0	WEE1	2	genetic interference	Srivas R (2016)	1
MAPK1	1	MTOR	14	genetic interference	Srivas R (2016)	1
AKT1	1	PPM1A	1	imaging technique	Chen TC (2014)	1
ATR	6	CLSPN	1	affinity chromatography technology	Chini CC (2003)	1
NFATC2	1	TUBA1A	13	affinity chromatography technology	Ishiguro K (2011)	1
CHEK2	2	WEE1	2	genetic interference	Srivas R (2016)	1
FZR1	1	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDC25A	2	SFN	1	affinity chromatography technology	Li X (2016)	1
AKT1	1	IL13RA2	0	two hybrid	Arroyo R (2015)	1
HNRNPD	3	MAP2K1	8	two hybrid	Lehner B (2004)	1
TP53	0	BLM	2	affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology	Sengupta S (2004), Sengupta S (2004), Sengupta S (2004), Wang XW (2001), Wang XW (2001), Wang XW (2001), Wang XW (2001), Garkavtsev IV (2001), Garkavtsev IV (2001), Yang Q (2002), Yang Q (2002), Wang J (2013)	12
FUS	0	HNRNPD	3	affinity chromatography technology, biochemical	Wang T (2014), Wan C (2015)	2
CDC14A	4	CDC25B	4	affinity chromatography technology, enzymatic study	Vazquez-Novelle MD (2010), Vazquez-Novelle MD (2010)	2
WEE1	2	BLM	2	genetic interference	Srivas R (2016)	1
XRCC6	3	MSH2	4	affinity chromatography technology, biochemical	Shahi A (2011), Kristensen AR (2012)	2
CDK1	0	MDM4	0	enzymatic study, affinity chromatography technology, affinity chromatography technology	Elias B (2005), Elias B (2005), Elias B (2005)	3
FBXO6	0	CDK1	0	affinity chromatography technology	Liu B (2012)	1
RAD51	3	HSP90AA1	7	two hybrid	Arroyo R (2015)	1
SH3PXD2A	4	23380	0	affinity chromatography technology	Boldt K (2016)	1
EIF4E2	2	23380	0	affinity chromatography technology	Boldt K (2016)	1
ARID1A	16	SMARCC1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology	Ryme J (2009), Ryme J (2009), Nagl NG (2005), Wang X (2004), Havugimana PC (2012), Wan C (2015), Dallas PB (1998)	7
LATS2	1	CDKN1A	1	enzymatic study	Suzuki H (2013)	1
TP53	0	TCEAL1	3	affinity chromatography technology	Huttlin EL (2015)	1
CSNK2A1	15	AKT1	1	enzymatic study	Di Maira G (2005)	1
COPS5	0	USP7	14	affinity chromatography technology	Bennett EJ (2010)	1
TOP2A	2	TOP1	1	biochemical	Wan C (2015)	1
UBE2T	0	FANCD2	3	enzymatic study	Hira A (2015)	1
MAPK1	1	ILKAP	2	biochemical	Wan C (2015)	1
TOP2A	2	WEE1	2	genetic interference	Srivas R (2016)	1
CHEK1	2	ATAD5	5	genetic interference	Srivas R (2016)	1
CLSPN	1	PCNA	0	affinity chromatography technology	Yang XH (2008)	1
HSP90AA1	7	XPO1	8	affinity chromatography technology	Falsone SF (2005)	1
CHEK1	2	MET	7	genetic interference	Shen JP (2017)	1
BRCA1	7	RFC1	1	biochemical, affinity chromatography technology	Wang Y (2000), Hill SJ (2014)	2
XRCC5	5	PCNA	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Matheos D (2002), Ohta S (2002), Balajee AS (2001)	3
FZR1	1	MET	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
TUBA1A	13	WRN	6	genetic interference	Srivas R (2016)	1
CHEK1	2	FEM1B	1	affinity chromatography technology, affinity chromatography technology	Sun TP (2009), Sun TP (2009)	2
CHEK1	2	LATS2	1	enzymatic study, enzymatic study	Okada N (2011), Suzuki H (2013)	2
NFATC2	1	SMARCC1	5	affinity chromatography technology	Gabriel CH (2016)	1
FANCD2	3	NBN	1	affinity chromatography technology	Nakanishi K (2002)	1
CDK9	3	MSH2	4	affinity chromatography technology	Mak AB (2010)	1
WEE1	2	ATAD5	5	genetic interference	Srivas R (2016)	1
BRCA1	7	CDK1	0	pull down	Wang H (1997)	1
NFATC2	1	TP53BP1	3	affinity chromatography technology	Gabriel CH (2016)	1
CHEK2	2	LATS2	1	enzymatic study	Okada N (2011)	1
CHEK1	2	CDC14A	4	genetic interference	Srivas R (2016)	1
TOP2A	2	COPS5	0	affinity chromatography technology, two hybrid, pull down	Chen MC (2011), Yun J (2004), Yun J (2004)	3
ZBTB21	2	CBY1	3	affinity chromatography technology	Boldt K (2016)	1
VCP	6	MTOR	14	affinity chromatography technology	Yu CC (2013)	1
CSNK2A1	15	TOP1	1	enzymatic study	Durban E (1985)	1
BRCA1	7	XPO1	8	affinity chromatography technology	Ertych N (2016)	1
COPS5	0	DTL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Olma MH (2009), Sertic S (2013), Higa LA (2006), Higa LA (2006)	5
WEE1	2	RB1	2	genetic interference	Srivas R (2016)	1
CHEK1	2	TUSC3	1	genetic interference	Srivas R (2016)	1
TCEAL1	3	USP11	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Sowa ME (2009), Sowa ME (2009), Sowa ME (2009), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	7
EIF4E2	2	CDC25B	4	affinity chromatography technology	Boldt K (2016)	1
CDC73	1	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Mak AB (2010), Herr P (2015)	2
AKT1	1	SRC	2	imaging technique, affinity chromatography technology	Chen TC (2014), Lee J (2013)	2
NEK9	1	CHEK1	2	affinity chromatography technology	Behrends C (2010)	1
POLA1	0	PCNA	0	biochemical, biochemical	Havugimana PC (2012), Wan C (2015)	2
ATM	9	TOPBP1	5	affinity chromatography technology	Perfettini JL (2009)	1
MTOR	14	TOP1	1	genetic interference	Shen JP (2017)	1
PTEN	24	VHL	0	genetic interference	Shen JP (2017)	1
WEE1	2	KIF13B	13	affinity chromatography technology	Boldt K (2016)	1
CHEK1	2	TP53	0	affinity chromatography technology, imaging technique, affinity chromatography technology, enzymatic study, enzymatic study	Tian H (2002), Sengupta S (2004), Tian H (2002), Goudelock DM (2003), Shieh SY (2000)	5
PRKDC	12	XRCC6	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, enzymatic study, affinity chromatography technology	Shao RG (1999), Drouet J (2005), Gottlieb TM (1993), Shamanna RA (2011), Shamanna RA (2011), Havugimana PC (2012), Sartorius CA (2000), Sartorius CA (2000), Hein MY (2015)	9
CSNK2A1	15	VHL	0	enzymatic study, affinity chromatography technology, affinity chromatography technology	Lolkema MP (2005), Lolkema MP (2005), Yang H (2007)	3
23380	0	CBY1	3	affinity chromatography technology	Boldt K (2016)	1
FANCD2	3	BLM	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pichierri P (2004), Pichierri P (2004), Chaudhury I (2014)	3
PRKDC	12	VHL	0	genetic interference	Shen JP (2017)	1
TCEAL1	3	USP7	14	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Huttlin EL (2015), Huttlin EL (2017)	3
LATS2	1	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
PRKDC	12	FANCD2	3	genetic interference	Aggarwal M (2013)	1
XPO1	8	CDC25B	4	affinity chromatography technology	Kirli K (2015)	1
COPS5	0	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Angers S (2006), He YJ (2006), McCall CM (2008), Bennett EJ (2010), Bennett EJ (2010), Bennett EJ (2010), Gastaldello S (2012), Olma MH (2009), Olma MH (2009), Rao F (2014), Pick E (2012), Groisman R (2003), Groisman R (2003), Huttlin EL (2015), Cavadini S (2016), Scherer PC (2016), Scherer PC (2016), Huttlin EL (2017)	19
BRCA1	7	UBA1	1	affinity chromatography technology	Ertych N (2016)	1
TARS	2	CHEK1	2	biochemical	Wan C (2015)	1
CASP8	1	XIAP	0	genetic interference, affinity chromatography technology, affinity chromatography technology	Guo Y (2002), Lee JS (2012), McDonald ER (2004)	3
MTOR	14	DDB1	6	affinity chromatography technology, affinity chromatography technology	Hussain S (2013), Hussain S (2013)	2
XPO1	8	EIF4E2	2	affinity chromatography technology	Kirli K (2015)	1
TP53	0	RPS10	0	two hybrid, affinity chromatography technology	Moon KD (2005), Fogeron ML (2013)	2
CHEK1	2	RAD17	2	genetic interference	Srivas R (2016)	1
SNW1	0	CDK1	0	affinity chromatography technology	Lleres D (2010)	1
FUS	0	HSP90AA1	7	affinity chromatography technology	Wang T (2014)	1
BRD4	8	RB1	2	genetic interference	Shen JP (2017)	1
SNW1	0	MSH6	2	affinity chromatography technology	Lleres D (2010)	1
RACGAP1	2	CHEK1	2	affinity chromatography technology	Huttlin EL (2017)	1
VAV1	2	MAPK1	1	affinity chromatography technology, affinity chromatography technology	Song JS (1996), Lee IS (1997)	2
NELL1	3	CHEK1	2	affinity chromatography technology	Huttlin EL (2017)	1
NFATC1	12	SMARCA4	19	affinity chromatography technology, affinity chromatography technology	Li X (2015), Gabriel CH (2016)	2
WRN	6	XRCC5	5	affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Karmakar P (2002), Karmakar P (2002), Li B (2000), Cooper MP (2000), Cooper MP (2000), Cooper MP (2000), Orren DK (2001), Li B (2004), Li B (2004), Sand-Dejmek J (2011), Sand-Dejmek J (2011), Partridge JJ (2003), Partridge JJ (2003), Hein MY (2015)	14
SFN	1	CDK1	0	affinity chromatography technology	Chan TA (1999)	1
EIF4E2	2	KCTD3	2	affinity chromatography technology	Boldt K (2016)	1
CDC25B	4	GIGYF1	15	affinity chromatography technology	Boldt K (2016)	1
MSH2	4	MSH6	2	biochemical, affinity chromatography technology, pull down, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, pull down, biochemical, affinity chromatography technology, imaging technique	Wang Y (2000), Wang Y (2003), Guerrette S (1998), Bocker T (1999), Bocker T (1999), Acharya S (1996), Matton N (2000), Matton N (2000), Yang Q (2004), Havugimana PC (2012), Gradia S (1997), Owen BA (2009), Wan C (2015), Hein MY (2015), Chen TC (2014)	15
DTL	0	SFN	1	affinity chromatography technology, affinity chromatography technology	Dar A (2014), Dar A (2014)	2
UBA1	1	FUS	0	affinity chromatography technology, affinity chromatography technology	Wang T (2014), Wang T (2014)	2
SFN	1	CBY1	3	affinity chromatography technology	Mancini M (2015)	1
MCPH1	4	ATM	9	imaging technique	Rai R (2006)	1
PARP1	3	RAD23A	1	affinity chromatography technology	Wu T (2013)	1
BRCA1	7	TTN	102	affinity chromatography technology	Ertych N (2016)	1
WEE1	2	CDC73	1	genetic interference	Srivas R (2016)	1
HECW2	13	FZR1	1	affinity chromatography technology, pull down, enzymatic study	Lu L (2013), Lu L (2013), Lu L (2013)	3
ATR	6	TOPBP1	5	affinity chromatography technology	Rendtlew Danielsen JM (2009)	1
TOP1	1	SNW1	0	unspecified method	Trzcinska AM (2002)	1
SH3PXD2A	4	ZBTB21	2	affinity chromatography technology	Boldt K (2016)	1
TOP1	1	RAD17	2	genetic interference	Srivas R (2016)	1
EIF4E2	2	CDC25C	0	affinity chromatography technology	Boldt K (2016)	1
CDC5L	2	FANCD2	3	affinity chromatography technology	Lleres D (2010)	1
BRCA1	7	PCNA	0	affinity chromatography technology, affinity chromatography technology	Hill SJ (2014), Ertych N (2016)	2
TNRC6B	10	CHEK1	2	affinity chromatography technology	Li S (2014)	1
HSP90AA1	7	CHEK1	2	affinity chromatography technology, pull down, affinity chromatography technology	Ha K (2011), Arlander SJ (2006), Taipale M (2012)	3
VCP	6	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yu CC (2013), Yu CC (2013), Fogeron ML (2013)	3
TUBA1A	13	TUSC3	1	genetic interference	Srivas R (2016)	1
BRCA1	7	RAD51	3	pull down, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Scully R (1997), Dong Y (2003), Dong Y (2003), Dong Y (2003), Wang Q (2001), Chen J (1998), Mok MT (2010), Scully R (1997), Scully R (1997), Johnson N (2013), Jung YS (2014), Jung YS (2014), Parameswaran B (2015)	13
CDC6	0	CDKN1A	1	pull down, imaging technique	Ramachandran N (2004), Chen TC (2014)	2
CHEK1	2	BRCA1	7	affinity chromatography technology, affinity chromatography technology, enzymatic study, genetic interference	Yarden RI (2002), Yarden RI (2002), Inoue Y (2007), Shen JP (2017)	4
MAPK1	1	TOP2A	2	pull down, enzymatic study	Shapiro PS (1999), Shapiro PS (1999)	2
BTG3	0	CHEK1	2	affinity chromatography technology, affinity chromatography technology	Cheng YC (2013), Cheng YC (2013)	2
TOP1	1	ATM	9	unspecified method	Trzcinska AM (2002)	1
KCTD3	2	23380	0	affinity chromatography technology	Boldt K (2016)	1
CHEK1	2	RFC1	1	genetic interference	Srivas R (2016)	1
RAD17	2	CLSPN	1	affinity chromatography technology, affinity chromatography technology	Wang X (2006), Wang X (2006)	2
CDK1	0	RACGAP1	2	enzymatic study	Toure A (2008)	1
CHEK1	2	RB1	2	enzymatic study, pull down	Inoue Y (2007), Inoue Y (2007)	2
FANCD2	3	FZR1	1	affinity chromatography technology, affinity chromatography technology	Lai F (2012), Lai F (2012)	2
WRN	6	VCP	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Partridge JJ (2003), Partridge JJ (2003), Indig FE (2004)	3
TP53	0	SFN	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Tian H (2002), Yang HY (2007), Yang HY (2003), Yang HY (2003), Choi HH (2011)	5
SH3PXD2A	4	CBY1	3	affinity chromatography technology	Boldt K (2016)	1
SH3PXD2A	4	CDC25B	4	affinity chromatography technology	Boldt K (2016)	1
CUL4A	2	USP7	14	affinity chromatography technology	Bennett EJ (2010)	1
HSP90AA1	7	TUBA1A	13	affinity chromatography technology, affinity chromatography technology	Hu Y (2003), Skarra DV (2011)	2
TP53	0	TOP1	1	affinity chromatography technology, two hybrid, affinity chromatography technology	Gobert C (1999), Mao Y (2002), Restle A (2008)	3
XPO1	8	RELA	1	affinity chromatography technology	Kirli K (2015)	1
CDC5L	2	PTBP1	2	affinity chromatography technology	Lleres D (2010)	1
KCTD3	2	ZBTB21	2	affinity chromatography technology	Boldt K (2016)	1
HSP90AA1	7	AKT1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Haendeler J (2003), Kawauchi K (2005), Sato S (2000), Basso AD (2002), Su CH (2011), Klein JB (2005), Sun L (2012)	7
TOP1	1	CHEK1	2	genetic interference	Srivas R (2016)	1
SH3PXD2A	4	CDC25C	0	affinity chromatography technology	Boldt K (2016)	1
ATM	9	SMO	0	genetic interference	Shen JP (2017)	1
ATXN3	2	HSP90AA1	7	affinity chromatography technology	Liu H (2016)	1
SMARCA4	19	TOPBP1	5	affinity chromatography technology	Cohen SM (2010)	1
XRCC5	5	NBN	1	affinity chromatography technology	Falck J (2005)	1
MSH2	4	ATR	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique	Wang Y (2003), Wang Y (2003), Wang Y (2003), Wang Y (2003), Pabla N (2011), Pabla N (2011), Pabla N (2011)	7
FUS	0	PCNA	0	affinity chromatography technology	Wang T (2014)	1
HSP90AA1	7	IGF1R	5	affinity chromatography technology	Taipale M (2012)	1
KSR1	0	CHEK1	2	affinity chromatography technology	Boldt K (2016)	1
CDC6	0	FZR1	1	pull down, enzymatic study, enzymatic study	Ke PY (2004), Petersen BO (2000), Cotto-Rios XM (2011)	3
KCTD3	2	LRFN1	4	affinity chromatography technology	Boldt K (2016)	1
CDC25A	2	RAD23A	1	affinity chromatography technology	Li X (2016)	1
ARID1A	16	CUL1	7	affinity chromatography technology	Jiang ZH (2015)	1
VHL	0	PARP1	3	affinity chromatography technology	Lai Y (2011)	1
DDB1	6	PCNA	0	affinity chromatography technology	Angers S (2006)	1
TP53	0	DDB1	6	affinity chromatography technology	Fogeron ML (2013)	1
RAD51	3	WRN	6	affinity chromatography technology, affinity chromatography technology, pull down, pull down, far western blotting	Otterlei M (2006), Otterlei M (2006), Otterlei M (2006), Otterlei M (2006), Otterlei M (2006)	5
CDKN1A	1	USP11	3	affinity chromatography technology	Fogeron ML (2013)	1
PTEN	24	DDB1	6	pull down	Verrastro I (2015)	1
MAPK1	1	CSNK2A1	15	enzymatic study, affinity chromatography technology, pull down	Ji H (2009), Ji H (2009), Ji H (2009)	3
BRCA1	7	SMARCC1	5	biochemical, affinity chromatography technology	Bochar DA (2000), Ertych N (2016)	2
CDC5L	2	PTBP3	0	affinity chromatography technology	Lleres D (2010)	1
CDK9	3	CUL1	7	affinity chromatography technology, affinity chromatography technology	Kiernan RE (2001), Garriga J (2003)	2
HNRNPD	3	PPM1A	1	affinity chromatography technology	Hein MY (2015)	1
RAD51	3	MSH6	2	affinity chromatography technology	Yang Q (2004)	1
DTL	0	MSH2	4	affinity chromatography technology	Jascur T (2011)	1
TP53BP1	3	BRCA1	7	affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Matsuoka S (2007), Wang B (2002), Bohgaki T (2011), Ertych N (2016)	4
CDC73	1	UBA2	0	genetic interference	Horlbeck MA (2018)	1
CSNK2A1	15	RELA	1	affinity chromatography technology, enzymatic study	Wang D (2000), Wang D (2000)	2
CHEK1	2	SMARCC1	5	genetic interference	Srivas R (2016)	1
PRKDC	12	BRCA1	7	unspecified method	Kim ST (1999)	1
RELA	1	PARP1	3	affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Hassa PO (2001), Hassa PO (2001), Hassa PO (2005), Hassa PO (2005), Hassa PO (2008), Hassa PO (2008)	6
CDK1	0	TP53BP1	3	enzymatic study, enzymatic study	van Vugt MA (2010), Benada J (2015)	2
IGF1R	5	TP53	0	affinity chromatography technology	Broussas M (2009)	1
MSH6	2	BLM	2	biochemical, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Yang Q (2004), Yang Q (2004)	3
CHRNA9	3	CHEK1	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ADA	0	CHEK1	2	genetic interference, genetic interference	Shen JP (2017), Srivas R (2016)	2
CDK9	3	TCEA1	0	affinity chromatography technology, pull down, imaging technique	Cojocaru M (2011), Cojocaru M (2011), Cojocaru M (2011)	3
BRCA1	7	VCP	6	affinity chromatography technology, pull down, affinity chromatography technology	Zhang H (2000), Zhang H (2000), Ertych N (2016)	3
XRCC6	3	TP53	0	affinity chromatography technology, affinity chromatography technology	Feki A (2005), Feki A (2005)	2
SFN	1	CSNK2A1	15	affinity chromatography technology	Benzinger A (2005)	1
BRCA1	7	DDB1	6	affinity chromatography technology, affinity chromatography technology	Hill SJ (2014), Ertych N (2016)	2
FZR1	1	PTEN	24	affinity chromatography technology, pull down, affinity chromatography technology	Song MS (2011), Song MS (2011), Choi BH (2014)	3
MSH6	2	CHEK1	2	affinity chromatography technology, affinity chromatography technology	Liu Y (2010), Liu Y (2010)	2
RB1	2	RFC1	1	affinity chromatography technology	van der Kuip H (1999)	1
CHEK1	2	PTEN	24	genetic interference	Shen JP (2017)	1
CHEK1	2	PIK3CA	8	genetic interference	Shen JP (2017)	1
RB1	2	FZR1	1	affinity chromatography technology, biochemical	Binne UK (2007), Binne UK (2007)	2
UBA1	1	UBE2T	0	pull down, enzymatic study	Jin J (2007), Huguenin-Dezot N (2016)	2
MCPH1	4	SMARCA4	19	affinity chromatography technology, affinity chromatography technology	Peng G (2009), Peng G (2009)	2
CHEK2	2	WRN	6	genetic interference	Srivas R (2016)	1
MAPK1	1	NEK2	2	two hybrid, affinity chromatography technology, pull down	Lou Y (2004), Lou Y (2004), Lou Y (2004)	3
SNW1	0	RACGAP1	2	affinity chromatography technology	Lleres D (2010)	1
APP	1	SRC	2	affinity chromatography technology	Austin SA (2009)	1
CHEK1	2	SETMAR	3	affinity chromatography technology	Williamson EA (2014)	1
COPS5	0	ZEB1	3	affinity chromatography technology, imaging technique	Zhang S (2017), Zhang S (2017)	2
ATR	6	TP53	0	pull down, unspecified method, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, genetic interference	Fabbro M (2004), Kim ST (1999), Lin WC (2001), Wang X (2011), Lakin ND (1999), Rocha S (2005), Dodson GE (2006), Kim ST (1999), Xie L (2013)	9
VCP	6	APP	1	affinity chromatography technology	Jang JK (2017)	1
TUBA1A	13	CDC14A	4	genetic interference	Srivas R (2016)	1
PCNA	0	XRCC6	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, fluorescent resonance energy transfe	Ohta S (2002), Ohta S (2002), Balajee AS (2001), Nicolae CM (2014)	4
TP53	0	USP7	14	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, x-ray crystallography, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, pull down, x-ray crystallography, unspecified method, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li M (2002), Li M (2002), Li M (2002), Li M (2002), Brooks CL (2007), Brooks CL (2007), Becker K (2007), Hu M (2006), Hu M (2006), Sarkari F (2010), Marchenko ND (2007), Epping MT (2011), Qing P (2011), Tang J (2006), Ma J (2010), Dai C (2011), Holowaty MN (2003), Sheng Y (2006), Sheng Y (2006), Sheng Y (2006), Yi P (2013), Yi P (2013), Zhang J (2014), Fang Z (2013), Ye M (2015), Lim KH (2015), Lim KH (2015), Reddy BA (2014), Reddy BA (2014)	29
IMPDH1	2	WEE1	2	genetic interference	Srivas R (2016)	1
NFATC2	1	PRKDC	12	affinity chromatography technology	Gabriel CH (2016)	1
KSR1	0	CDC25B	4	affinity chromatography technology	Boldt K (2016)	1
VCP	6	SMARCC1	5	affinity chromatography technology	Yu CC (2013)	1
RPS10	0	APP	1	pull down, pull down	Olah J (2011), Virok DP (2011)	2
FBXO6	0	PRKDC	12	affinity chromatography technology	Liu B (2012)	1
CHEK1	2	NEK2	2	biochemical	Kraemer A (2004)	1
TCEAL1	3	CHEK1	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
AKT1	1	CDKN1A	1	pull down, enzymatic study, imaging technique, enzymatic study	Heron-Milhavet L (2006), Heron-Milhavet L (2006), Chen TC (2014), Roessig L (2001)	4
MDM4	0	APP	1	pull down	Olah J (2011)	1
PCNA	0	DTL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Jascur T (2011), Jascur T (2011), Dar A (2014), Terai K (2010), Higa LA (2006), Higa LA (2006)	6
IGF1R	5	PRKDC	12	genetic interference	Shen JP (2017)	1
HECW2	13	CSNK2A1	15	affinity chromatography technology	Lu L (2013)	1
BLM	2	VCP	6	genetic interference	Vizeacoumar FJ (2013)	1
USP11	3	TP53	0	affinity chromatography technology, affinity chromatography technology, enzymatic study	Sowa ME (2009), Ke JY (2014), Ke JY (2014)	3
NFATC1	12	NFATC2	1	affinity chromatography technology	Gabriel CH (2016)	1
FUS	0	VCP	6	affinity chromatography technology, affinity chromatography technology	Wang T (2014), Wang T (2014)	2
NFATC2	1	CHEK1	2	affinity chromatography technology, affinity chromatography technology	Gabriel CH (2016), Gabriel CH (2016)	2
UBA2	0	CHEK1	2	pull down	Tan X (2015)	1
XRCC5	5	PRKDC	12	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, biochemical, affinity chromatography technology	Jin S (1997), Matheos D (2002), Gell D (1999), Drouet J (2005), Falck J (2005), Falck J (2005), Falck J (2005), Olsen BB (2012), Olsen BB (2012), Sand-Dejmek J (2011), Sartorius CA (2000), Sartorius CA (2000), Drouet J (2006), Drouet J (2006), Sibanda BL (2010), Wan C (2015), Hein MY (2015)	17
WEE1	2	CDC6	0	genetic interference	Srivas R (2016)	1
NFATC1	12	TP53	0	affinity chromatography technology	Li X (2015)	1
CDC25C	0	LRFN1	4	affinity chromatography technology	Boldt K (2016)	1
CTSE	0	CHEK1	2	affinity chromatography technology	Huttlin EL (2017)	1
BRCA1	7	MSH2	4	two hybrid, pull down, biochemical, affinity chromatography technology, genetic interference	Wang Q (2001), Wang Q (2001), Wang Y (2000), Wada-Hiraike O (2005), Peng M (2014)	5
GIGYF1	15	KIF13B	13	affinity chromatography technology	Boldt K (2016)	1
TP53	0	MSH6	2	affinity chromatography technology	Yang Q (2004)	1
CHEK1	2	MEN1	1	affinity chromatography technology, affinity chromatography technology	Gallo A (2010), Gallo A (2010)	2
ZEB1	3	USP7	14	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Zhang P (2014), Zhang P (2014), Zhang P (2014), Zhou Z (2017), Zhou Z (2017)	5
ATR	6	PIK3CA	8	unspecified method	Kim ST (1999)	1
CHEK2	2	ATAD5	5	genetic interference	Srivas R (2016)	1
TOP2A	2	RB1	2	affinity chromatography technology, affinity chromatography technology	Bhat UG (1999), Bhat UG (1999)	2
CHEK1	2	BLM	2	affinity chromatography technology, imaging technique, genetic interference	Sengupta S (2004), Sengupta S (2004), Srivas R (2016)	3
VCP	6	CDK1	0	affinity chromatography technology	Yu CC (2013)	1
WEE1	2	BRD4	8	genetic interference	Srivas R (2016)	1
IGF1R	5	APP	1	pull down	Olah J (2011)	1
TP53	0	MEN1	1	pull down	Dou Y (2005)	1
TOP3A	0	WEE1	2	genetic interference	Srivas R (2016)	1
COPS5	0	PARP1	3	affinity chromatography technology	Bennett EJ (2010)	1
XPO1	8	WEE1	2	affinity chromatography technology	Kirli K (2015)	1
PARP1	3	PCNA	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Frouin I (2003), Cazzalini O (2010), Cazzalini O (2010), Lee CH (2010), Pozo FM (2011), Sekimoto T (2010)	6
SETMAR	3	TOP2A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Williamson EA (2008), Wray J (2009), Wray J (2009)	3
CHEK2	2	FZR1	1	genetic interference	Srivas R (2016)	1
PRKDC	12	TP53	0	unspecified method, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Kim ST (1999), Goudelock DM (2003), Yavuzer U (1998), Maiti AK (2010), Shieh SY (1997), Chan DW (2000), Kim ST (1999), Sakaguchi K (1998), Borcherds W (2014)	9
CHEK1	2	CDC6	0	genetic interference	Srivas R (2016)	1
CUL1	7	TARS	2	affinity chromatography technology	Bennett EJ (2010)	1
HNRNPD	3	VEGFA	3	unspecified method, affinity chromatography technology, affinity chromatography technology, unspecified method	Xin H (2011), Xin H (2011), Kishor A (2013), Kishor A (2013)	4
CDC5L	2	COPS5	0	affinity chromatography technology	Lleres D (2010)	1
CDC5L	2	DDB1	6	affinity chromatography technology	Lleres D (2010)	1
MAPK1	1	CHEK1	2	biochemical	Wan C (2015)	1
RB1	2	CDKN1A	1	affinity chromatography technology, pull down	Nakanishi M (1999), Nakanishi M (1999)	2
SNW1	0	MSH2	4	affinity chromatography technology, affinity chromatography technology	Zhang C (2003), Lleres D (2010)	2
FBXO6	0	RPS10	0	affinity chromatography technology	Liu B (2012)	1
CDC5L	2	CDC73	1	affinity chromatography technology	Lleres D (2010)	1
CHEK1	2	FUS	0	affinity chromatography technology	So J (2015)	1
HECW2	13	CHEK1	2	affinity chromatography technology	Lu L (2013)	1
TUBA1A	13	CDC73	1	genetic interference	Srivas R (2016)	1
CUL4A	2	VCP	6	affinity chromatography technology	Besten Wd (2012)	1
HSP90AA1	7	MDM4	0	affinity chromatography technology	Taipale M (2012)	1
FZR1	1	VHL	0	affinity chromatography technology, affinity chromatography technology	Liu W (2011), Liu W (2011)	2
CDK1	0	XIAP	0	enzymatic study	Hou Y (2017)	1
RAD51	3	MCPH1	4	imaging technique, affinity chromatography technology, affinity chromatography technology, imaging technique	Liang Y (2010), Wu X (2009), Wu X (2009), Wu X (2009)	4
CSNK2A1	15	BRCA1	7	pull down	OBrien KA (1999)	1
MDM4	0	NBN	1	affinity chromatography technology	Carrillo AM (2015)	1
COPS5	0	BLM	2	affinity chromatography technology	Bennett EJ (2010)	1
TOP3A	0	MSH2	4	genetic interference	Srivas R (2016)	1
HNRNPD	3	BRCA1	7	affinity chromatography technology, two hybrid, affinity chromatography technology	Shimizu Y (2012), Lehner B (2004), Ertych N (2016)	3
COPS5	0	VCP	6	affinity chromatography technology, affinity chromatography technology, pull down, biochemical, affinity chromatography technology	Cayli S (2009), Cayli S (2009), Cayli S (2009), Cayli S (2009), Bennett EJ (2010)	5
CDKN1A	1	PARP1	3	pull down, pull down, affinity chromatography technology, affinity chromatography technology	Frouin I (2003), Cazzalini O (2010), Cazzalini O (2010), Lee CH (2010)	4
CASP8	1	MAPK1	1	affinity chromatography technology	Yao Z (2007)	1
TP53	0	CDK9	3	genetic interference, pull down, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology	De Falco G (2000), Claudio PP (2006), Claudio PP (2006), Claudio PP (2006), Claudio PP (2006), Claudio PP (2006)	6
VHL	0	HSP90AA1	7	affinity chromatography technology, genetic interference	Yang C (2013), Shen JP (2017)	2
CDC5L	2	ATR	6	affinity chromatography technology, affinity chromatography technology	Zhang N (2009), Zhang N (2009)	2
ADA	0	BLM	2	genetic interference	Srivas R (2016)	1
PRKDC	12	RAD17	2	unspecified method	Kim ST (1999)	1
CDC25B	4	LRFN1	4	affinity chromatography technology	Boldt K (2016)	1
TLK1	5	NBN	1	enzymatic study	Krause DR (2003)	1
ADA	0	PTEN	24	genetic interference	Shen JP (2017)	1
CDC5L	2	CDKN1A	1	pull down	Ramachandran N (2004)	1
CHEK2	2	RAD17	2	genetic interference	Srivas R (2016)	1
CHEK1	2	TLK1	5	enzymatic study	Krause DR (2003)	1
ATM	9	FANCD2	3	pull down, affinity chromatography technology, two hybrid, enzymatic study	Taniguchi T (2002), Taniguchi T (2002), Reuter TY (2003), Taniguchi T (2002)	4
XRCC5	5	XRCC6	3	two hybrid, biochemical, two hybrid, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, enzymatic study, x-ray crystallography, affinity chromatography technology, pull down, biochemical, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, imaging technique, affinity chromatography technology, affinity chromatography technology	Gell D (1999), Barlev NA (1998), Yang CR (1999), Singleton BK (1999), Song K (2000), Gell D (1999), Gell D (1999), Willis DM (2002), Willis DM (2002), Drouet J (2005), Drouet J (2005), Cohen HY (2004), Lan L (2010), Cooper MP (2000), Cooper MP (2000), Velma V (2010), Zheng Y (2011), Sucharov CC (2004), Sucharov CC (2004), Sibani S (2005), Sibani S (2005), Walker JR (2001), Nick McElhinny SA (2000), Nick McElhinny SA (2000), Sand-Dejmek J (2011), Sand-Dejmek J (2011), Sand-Dejmek J (2011), Pucci S (2009), Trougakos IP (2009), Havugimana PC (2012), Sartorius CA (2000), Sartorius CA (2000), Rivera-Calzada A (2007), Kelavkar UP (2001), Kelavkar UP (2001), Kristensen AR (2012), Kim E (2008), Wan C (2015), Hein MY (2015), Hein MY (2015), Nolens G (2009), Nolens G (2009), Nolens G (2009), Nolens G (2009), Huttlin EL (2017), Fantini D (2017)	46
COPS5	0	VHL	0	affinity chromatography technology	Bemis L (2004)	1
NBN	1	CHEK1	2	genetic interference	Pichierri P (2004)	1
DENND1A	2	ZBTB21	2	affinity chromatography technology	Boldt K (2016)	1
NBN	1	PRKDC	12	pull down, affinity chromatography technology	Falck J (2005), Falck J (2005)	2
CHEK2	2	CDC6	0	genetic interference	Srivas R (2016)	1
XPO1	8	GIGYF1	15	affinity chromatography technology	Kirli K (2015)	1
ATM	9	BRCA1	7	affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, pull down, pull down, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Gatei M (2000), Gatei M (2000), Kim ST (1999), Cortez D (1999), Cortez D (1999), Tibbetts RS (2000), Wang Y (2000), Mu JJ (2007), Tsai WB (2008), Gatei M (2000), Gatei M (2000), Gatei M (2000)	12
TP53BP1	3	BLM	2	affinity chromatography technology, affinity chromatography technology, imaging technique	Sengupta S (2004), Sengupta S (2004), Sengupta S (2004)	3
RFC1	1	RAD17	2	biochemical, affinity chromatography technology	Tomida J (2008), Dahm K (2002)	2
CUL1	7	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Taipale M (2012)	2
SFN	1	WEE1	2	affinity chromatography technology	Benzinger A (2005)	1
DENND1A	2	KCTD3	2	affinity chromatography technology	Boldt K (2016)	1
CDK1	0	FZR1	1	enzymatic study, affinity chromatography technology	Gutierrez GJ (2010), Huttlin EL (2017)	2
XPO1	8	KCTD3	2	affinity chromatography technology	Kirli K (2015)	1
DENND1A	2	LRFN1	4	affinity chromatography technology	Boldt K (2016)	1
DHFR	0	CDC73	1	genetic interference	Srivas R (2016)	1
BCL2L1	0	TP53	0	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Vinayagam A (2011), Tang WH (2014), Saxena R (2016), Stegh AH (2010), Kim EM (2014)	5
XRCC6	3	MSH6	2	two hybrid, affinity chromatography technology, affinity chromatography technology, biochemical	Shahi A (2011), Shahi A (2011), Shahi A (2011), Kristensen AR (2012)	4
CUL4A	2	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Guerrero-Santoro J (2008), Guerrero-Santoro J (2008), Angers S (2006), Angers S (2006), Jin J (2006), Wang H (2006), Kapetanaki MG (2006), Matsuda N (2005), Hu J (2004), Hu J (2004), Hu J (2004), Ahn J (2010), Maddika S (2009), Fischer ES (2011), Tan L (2007), He YJ (2006), He YJ (2006), He YJ (2006), McCall CM (2008), McCall CM (2008), Shiyanov P (1999), Bennett EJ (2010), Gastaldello S (2012), Kanei-Ishii C (2012), Hodgson AJ (2012), Kulaksiz G (2005), Wu Z (2012), Wu Z (2012), Olma MH (2009), Olma MH (2009), Havugimana PC (2012), Rao F (2014), Wan C (2015), Liu Y (2015), Zha Z (2015), Mouysset J (2015), Gao J (2015), Yang Y (2016), Yang Y (2016), Scherer PC (2016), Eichner R (2016), Mo Y (2017), Mo Y (2017), Peng Z (2016), Higa LA (2006), Ohtake F (2007)	46
CDC25C	0	HSP90AA1	7	affinity chromatography technology	Garcia-Morales P (2007)	1
PCNA	0	WRN	6	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, fluorescent resonance energy transfe	Rodriguez-Lopez AM (2003), Rodriguez-Lopez AM (2003), Huang S (2000), Kobayashi J (2010), Baynton K (2003)	5
KSR1	0	KCTD3	2	affinity chromatography technology	Boldt K (2016)	1
BCL2L14	2	COPS5	0	two hybrid, affinity chromatography technology, pull down	Liu X (2008), Liu X (2008), Liu X (2008)	3
CHEK1	2	TCEA1	0	genetic interference	Srivas R (2016)	1
PTBP1	2	APP	1	pull down	Olah J (2011)	1
VAV1	2	TUBA1A	13	affinity chromatography technology, affinity chromatography technology, pull down	Huby RD (1995), Huby RD (1995), Huby RD (1995)	3
TOP3A	0	RAD17	2	genetic interference	Srivas R (2016)	1
CDC5L	2	HSP90AA1	7	affinity chromatography technology	Lleres D (2010)	1
POLA1	0	PARP1	3	affinity chromatography technology, far western blotting	Dantzer F (1998), Dantzer F (1998)	2
TARS	2	HNRNPD	3	biochemical	Wan C (2015)	1
CHEK1	2	FHIT	0	genetic interference	Srivas R (2016)	1
MAPK1	1	TP53	0	affinity chromatography technology, affinity chromatography technology, protein complementation assay, affinity chromatography technology, imaging technique	Persons DL (2000), How PC (2011), Srivastav RK (2011), Fogeron ML (2013), Chen TC (2014)	5
BCL2L1	0	MTOR	14	affinity chromatography technology, enzymatic study	Ramanathan A (2009), Ramanathan A (2009)	2
PARP1	3	TP53	0	affinity chromatography technology, far western blotting, pull down, affinity chromatography technology, pull down, pull down	Gueven N (2004), Malanga M (1998), Vaziri H (1997), Vaziri H (1997), Wesierska-Gadek J (2003), Simbulan-Rosenthal CM (2003)	6
UBE2T	0	BRCA1	7	pull down	Ueki T (2009)	1
SNW1	0	PRKDC	12	affinity chromatography technology	Lleres D (2010)	1
IGF1R	5	MTOR	14	genetic interference	Shen JP (2017)	1
CSNK2A1	15	USP7	14	enzymatic study, enzymatic study	Carra G (2017), Khoronenkova SV (2012)	2
TP53	0	MET	7	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ERCC6L	3	CHEK1	2	affinity chromatography technology	Huttlin EL (2017)	1
MSH6	2	XRCC5	5	affinity chromatography technology	Shahi A (2011)	1
SNW1	0	DDB1	6	affinity chromatography technology	Zhang C (2003)	1
DDB1	6	DTL	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jin J (2006), Jin J (2006), Jin J (2006), Higa LA (2006), Rossi M (2013), Shibata E (2011), Higa LA (2006), Higa LA (2006)	8
VHL	0	TP53	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Roe JS (2006), Roe JS (2006), Roe JS (2006), Lai Y (2011), Lai Y (2011)	5
TOP3A	0	CHEK1	2	genetic interference	Srivas R (2016)	1
CHEK1	2	BCL2L1	0	enzymatic study	Wang J (2012)	1
NFATC1	12	PARP1	3	affinity chromatography technology, pull down	Valdor R (2008), Valdor R (2008)	2
TP53	0	HECW2	13	affinity chromatography technology	Miyazaki K (2003)	1
PRKDC	12	CHEK1	2	unspecified method, pull down, genetic interference	Kim ST (1999), Goudelock DM (2003), Shen JP (2017)	3
VCP	6	NEK2	2	affinity chromatography technology	Yu CC (2013)	1
TOP1	1	CDC6	0	genetic interference	Srivas R (2016)	1
CHEK1	2	UBE2T	0	enzymatic study	Lv Z (2017)	1
CHEK1	2	DAAM1	3	genetic interference	Srivas R (2016)	1
PTEN	24	AKT1	1	affinity chromatography technology, fluorescent resonance energy transfe	Mistafa O (2010), Ivanov AA (2017)	2
CHEK1	2	SFN	1	affinity chromatography technology	Tian H (2002)	1
PCNA	0	FANCD2	3	affinity chromatography technology, affinity chromatography technology, pull down, biochemical	Howlett NG (2009), Howlett NG (2009), Howlett NG (2009), Chen X (2016)	4
CHEK1	2	MAP2K1	8	genetic interference	Shen JP (2017)	1
AKT1	1	CHEK1	2	genetic interference	Shen JP (2017)	1
CDC25B	4	CBY1	3	affinity chromatography technology	Boldt K (2016)	1
FUS	0	RELA	1	affinity chromatography technology, pull down	Uranishi H (2001), Uranishi H (2001)	2
MDM4	0	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
COPS5	0	TOP1	1	affinity chromatography technology	Bennett EJ (2010)	1
NFATC1	12	TUBA1A	13	pull down	Ishiguro K (2011)	1
HSP90AA1	7	NEK9	1	affinity chromatography technology, affinity chromatography technology	Taipale M (2012), Taipale M (2012)	2
CHEK1	2	USP11	3	genetic interference	Srivas R (2016)	1
TUBA1A	13	RB1	2	genetic interference	Srivas R (2016)	1
PRKDC	12	FZR1	1	affinity chromatography technology, affinity chromatography technology	Shang ZF (2015), Shang ZF (2015)	2
EIF4E2	2	APP	1	pull down	Olah J (2011)	1
HNRNPD	3	SFN	1	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology	He C (2006), He C (2006), He C (2006), He C (2006), He C (2006)	5
CSNK2A1	15	XRCC5	5	enzymatic study	Olsen BB (2010)	1
CUL1	7	HNRNPD	3	affinity chromatography technology	Bennett EJ (2010)	1
MSH2	4	CHEK1	2	affinity chromatography technology	Adamson AW (2005)	1
SNW1	0	HSP90AA1	7	affinity chromatography technology	Lleres D (2010)	1
ZEB1	3	ATM	9	affinity chromatography technology, enzymatic study	Zhang P (2014), Zhang P (2014)	2
TCEA1	0	APP	1	pull down	Olah J (2011)	1
POLA1	0	TP53	0	affinity chromatography technology	Melle C (2002)	1
ATXN3	2	CUL1	7	affinity chromatography technology	Tu Y (2017)	1
IMPDH1	2	CHEK1	2	genetic interference	Srivas R (2016)	1
COPS5	0	FUS	0	affinity chromatography technology	Bennett EJ (2010)	1
FBXO6	0	MET	7	affinity chromatography technology	Liu B (2012)	1
PTEN	24	USP7	14	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Wu Y (2013), Zhang J (2013), Zhang J (2013), Yuan L (2015)	4
COPS5	0	TP53	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, far western blotting, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang XC (2008), Zhang XC (2008), Zhang XC (2008), Wang J (2006), Bech-Otschir D (2001), Bech-Otschir D (2001), Oh W (2006), Bhansali M (2014), Bhansali M (2014)	9
TOP1	1	XRCC6	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Ando K (2017), Ando K (2017), Ando K (2017), Ando K (2017)	4
BLM	2	RFC1	1	biochemical	Wang Y (2000)	1
MSH2	4	BLM	2	biochemical, affinity chromatography technology	Wang Y (2000), Yang Q (2004)	2
CUL1	7	FZR1	1	affinity chromatography technology, affinity chromatography technology	Fukushima H (2013), Fukushima H (2013)	2
USP11	3	UBA1	1	affinity chromatography technology	Hein MY (2015)	1
FUS	0	TUBA1A	13	affinity chromatography technology	Wang T (2014)	1
PCNA	0	PRKDC	12	affinity chromatography technology	Ohta S (2002)	1
COPS5	0	SMARCA4	19	affinity chromatography technology	Bennett EJ (2010)	1
RELA	1	MED15	6	pull down	Naeaer AM (1999)	1
CHEK1	2	FANCD2	3	enzymatic study, genetic interference	Zhi G (2009), Pichierri P (2004)	2
NBN	1	BLM	2	biochemical	Wang Y (2000)	1
PTBP3	0	APP	1	pull down	Olah J (2011)	1
BRCA1	7	MAPK1	1	affinity chromatography technology, affinity chromatography technology	Yan Y (2008), Yan Y (2008)	2
PARP1	3	BRCA1	7	affinity chromatography technology, affinity chromatography technology, enzymatic study, genetic interference, genetic interference, affinity chromatography technology	Hu Y (2014), Hu Y (2014), Hu Y (2014), Shen JP (2017), Srivas R (2016), Ertych N (2016)	6
ATXN3	2	CUL4A	2	affinity chromatography technology, affinity chromatography technology	Tu Y (2017), Tu Y (2017)	2
CHEK1	2	CDC25A	2	pull down, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology	Goloudina A (2003), Sanchez Y (1997), Sanchez Y (1997), Zhao H (2002), Jin J (2008), Hassepass I (2003), Sorensen CS (2003), Li X (2016)	8
ATM	9	WRN	6	unspecified method	Kim ST (1999)	1
RB1	2	SNW1	0	pull down, pull down	Prathapam T (2002), Prathapam T (2002)	2
MSH2	4	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
WEE1	2	CBY1	3	affinity chromatography technology	Boldt K (2016)	1
BRD4	8	PTEN	24	genetic interference	Shen JP (2017)	1
TP53BP1	3	MAPK1	1	affinity chromatography technology	Woods NT (2012)	1
CDC73	1	PCNA	0	affinity chromatography technology	Herr P (2015)	1
CHEK1	2	FBXO6	0	affinity chromatography technology	Tu Y (2017)	1
FBXO6	0	TUSC3	1	affinity chromatography technology	Liu B (2012)	1
CHEK2	2	BRD4	8	genetic interference	Srivas R (2016)	1
CUL4A	2	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dias DC (2002), Bennett EJ (2010), Taipale M (2012)	3
ATXN3	2	VCP	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, biochemical, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Doss-Pepe EW (2003), Wang Q (2008), Matsumoto M (2004), Matsumoto M (2004), Reina CP (2010), Zhong X (2006), Morreale G (2009), Fernandez-Saiz V (2010), Laco MN (2012), Laco MN (2012), Yu CC (2013), Liu S (2013), Yang H (2014), Yang H (2014), Yang H (2014), Liu H (2016), Pfeiffer A (2017), Tu Y (2017)	18
BLM	2	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Bhattacharyya S (2009), Bhattacharyya S (2009)	2
CDC73	1	RAD51	3	affinity chromatography technology	Hein MY (2015)	1
CDK1	0	CDC6	0	enzymatic study	Jiang W (1999)	1
TOP2A	2	CSNK2A1	15	affinity chromatography technology, enzymatic study, biochemical	Chen MC (2011), Zhang M (2011), Wan C (2015)	3
VCP	6	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Alexandru G (2008), Besten Wd (2012), Zhang Z (2015)	3
BRD4	8	CUL1	7	affinity chromatography technology	Dai X (2017)	1
AKT1	1	SMARCC1	5	affinity chromatography technology, enzymatic study, pull down	Foster KS (2006), Foster KS (2006), Foster KS (2006)	3
XPO1	8	CLSPN	1	affinity chromatography technology	Kirli K (2015)	1
MAPK1	1	MAP2K1	8	affinity chromatography technology, enzymatic study, two hybrid, pull down, pull down, pull down, enzymatic study, affinity chromatography technology, enzymatic study, protein complementation assay, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Sanz-Moreno V (2003), Sanz-Moreno V (2003), Robinson FL (2002), Yeung K (2000), Yeung K (2000), Wunderlich W (2001), Xu Be (2001), Xu Be (2001), Chen Z (2001), Srivastav RK (2011), Kubota Y (2011), Ho DT (2003), Wang J (2009), Jahrling JB (2014)	14
CHEK1	2	FANCE	6	enzymatic study	Wang X (2007)	1
RB1	2	CDK9	3	pull down, affinity chromatography technology, enzymatic study, enzymatic study, biochemical, enzymatic study	Simone C (2002), Simone C (2002), De Luca A (1997), Garriga J (1996), Garriga J (1996), Grana X (1994)	6
CDKN1A	1	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Abbas T (2008), Abbas T (2008), Gao J (2015)	3
BRD4	8	DHFR	0	genetic interference	Shen JP (2017)	1
CHEK1	2	PIGM	1	two hybrid	Wang J (2011)	1
CHEK1	2	XPO1	8	pull down	Jiang K (2003)	1
TIMELESS	8	CHEK1	2	affinity chromatography technology	Unsal-Kacmaz K (2005)	1
KCTD3	2	CBY1	3	affinity chromatography technology	Boldt K (2016)	1
CUL1	7	TOP1	1	affinity chromatography technology	Bennett EJ (2010)	1
BLM	2	TOP3A	0	pull down, far western blotting, affinity chromatography technology, imaging technique, far western blotting, affinity chromatography technology, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wu L (2000), Freire R (2001), Freire R (2001), Hu P (2001), Brosh RM (2000), Wu L (2000), Wu L (2000), Hu P (2001), Hu P (2001), Meetei AR (2003), Meetei AR (2003), Meetei AR (2003), Wang J (2013), Hein MY (2015)	14
HNRNPD	3	CHEK1	2	biochemical	Wan C (2015)	1
PCNA	0	RAD51	3	affinity chromatography technology, imaging technique	Chen X (2016), Sato K (2016)	2
CUL1	7	CDKN1A	1	affinity chromatography technology	Yu ZK (1998)	1
TUBA1A	13	WEE1	2	genetic interference	Srivas R (2016)	1
CUL1	7	DDB1	6	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Gastaldello S (2012)	2
TUBA1A	13	LLGL1	9	genetic interference	Srivas R (2016)	1
TOP2A	2	CDC73	1	genetic interference	Srivas R (2016)	1
TP53BP1	3	CHEK1	2	imaging technique	Sengupta S (2004)	1
CSNK2A1	15	CDK1	0	enzymatic study	Russo GL (1992)	1
PTBP3	0	CHEK1	2	biochemical	Wan C (2015)	1
SMARCA4	19	ARID1A	16	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology	Wang W (1996), Zhao K (1998), Pal S (2003), Bultman SJ (2005), Wang X (2004), Trotter KW (2008), Tando T (2010), Havugimana PC (2012), Wan C (2015), Dallas PB (1998)	10
DENND1A	2	23380	0	affinity chromatography technology	Boldt K (2016)	1
XRCC5	5	BRCA1	7	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Wei L (2008), Wei L (2008), Jiang G (2013), Jiang G (2013), Jiang G (2013), Ertych N (2016)	6
CDK9	3	HNRNPD	3	affinity chromatography technology	Jeronimo C (2007)	1
CDKN1A	1	MSH2	4	two hybrid	Vinayagam A (2011)	1
CHEK1	2	SRC	2	genetic interference	Shen JP (2017)	1
ATM	9	CDK9	3	imaging technique	Fang L (2014)	1
SRC	2	TP53	0	enzymatic study	Huang YF (2014)	1
LATS2	1	GIGYF1	15	bioid	Couzens AL (2013)	1
MSH6	2	PCNA	0	far western blotting, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, far western blotting, affinity chromatography technology, biochemical, affinity chromatography technology	Kleczkowska HE (2001), Kleczkowska HE (2001), Clark AB (2000), Ohta S (2002), Jascur T (2011), Schoepf B (2012), Havugimana PC (2012), Dzantiev L (2004), Han J (2014), Wan C (2015), Hein MY (2015)	11
XRCC5	5	ATM	9	pull down	Falck J (2005)	1
COPS5	0	PRKDC	12	affinity chromatography technology	Bennett EJ (2010)	1
NFATC1	12	ARID1A	16	affinity chromatography technology	Gabriel CH (2016)	1
XRCC5	5	DDB1	6	affinity chromatography technology	Fantini D (2017)	1
CDC25B	4	KIF13B	13	affinity chromatography technology	Boldt K (2016)	1
BLM	2	PARP1	3	affinity chromatography technology	Wang J (2013)	1
ATM	9	VHL	0	affinity chromatography technology, genetic interference	Roe JS (2006), Shen JP (2017)	2
CUL1	7	CHEK1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Liu S (2009), Huh J (2013), Zhang YW (2005)	3
CHEK1	2	CBY1	3	affinity chromatography technology	Boldt K (2016)	1
CDC5L	2	ERCC6L	3	affinity chromatography technology	Lleres D (2010)	1
FBXO6	0	TUBA1A	13	affinity chromatography technology	Liu B (2012)	1
VEGFA	3	HSP90AA1	7	affinity chromatography technology	Park JH (2008)	1
CHEK1	2	TTN	102	genetic interference	Srivas R (2016)	1
CDK1	0	BCL2L1	0	affinity chromatography technology, affinity chromatography technology, imaging technique	Wang J (2012), Wang J (2012), Wang J (2012)	3
TOP1	1	MSH2	4	genetic interference	Srivas R (2016)	1
XRCC5	5	RFC1	1	affinity chromatography technology, biochemical	Matheos D (2002), Wan C (2015)	2
NFATC2	1	SMARCA4	19	affinity chromatography technology	Gabriel CH (2016)	1
ATM	9	TP53BP1	3	pull down, enzymatic study, enzymatic study	Fernandez-Capetillo O (2002), Ward IM (2003), Lee H (2009)	3
XPO1	8	DENND1A	2	affinity chromatography technology	Kirli K (2015)	1
MDM4	0	TP53	0	enzymatic study, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, protein complementation assay, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, protein complementation assay, affinity chromatography technology, affinity chromatography technology, unspecified method, x-ray crystallography, unspecified method, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, x-ray crystallography, protein complementation assay, affinity chromatography technology, unspecified method, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, fluorescent resonance energy transfe, pull down	Badciong JC (2002), Shvarts A (1997), Shvarts A (1997), Tang Y (2008), Okamoto K (2005), Chen L (2005), Wang X (2001), Ohtsubo C (2009), Zdzalik M (2010), Singh RK (2007), Kim S (2010), Li M (2011), Li M (2011), David Y (2011), de Graaf P (2003), Wade M (2012), Wade M (2012), Wade M (2012), Stad R (2000), Stad R (2000), Bernal F (2010), Bernal F (2010), Bernal F (2010), Bernal F (2010), Miller KR (2010), Zuckerman V (2009), Kallen J (2009), Czarna A (2009), Czarna A (2009), Popowicz GM (2008), Hu B (2007), Sharp DA (1999), Li C (2002), Di Conza G (2012), Mancini F (2009), Mancini F (2009), Wu S (2012), Shan B (2012), Wu S (2012), Wu S (2012), Ranaweera RS (2013), Bista M (2013), Bista M (2013), Wang CL (2014), Wang CL (2014), Rallapalli R (1999), Chang YS (2013), Chang YS (2013), Tan BX (2014), Huttlin EL (2015), Sanchez MC (2010), Sanchez MC (2010), Li YC (2014), Li X (2015), Chen X (2015), Chen L (2015), Chen L (2015), Chen L (2015), Wei X (2016), Wei X (2016), Xie X (2016), Huttlin EL (2017), Borcherds W (2017), Shangary S (2008), Ivanov AA (2017), Mancini F (2016)	66
ATR	6	FANCD2	3	enzymatic study, imaging technique, enzymatic study	Ho GP (2006), Pichierri P (2004), Shigechi T (2012)	3
LRRC6	0	CHEK1	2	affinity chromatography technology	Huttlin EL (2017)	1
DDB1	6	COPS5	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study	Angers S (2006), Jin J (2006), Emberley ED (2012), Bennett EJ (2010), Olma MH (2009), He F (2013)	6
MAP2K1	8	MTOR	14	genetic interference	Srivas R (2016)	1
TP53	0	CDKN1A	1	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, imaging technique	Tian H (2002), Vinayagam A (2011), Kinyamu HK (2003), Giono LE (2007), Chen TC (2014)	5
VAV1	2	XRCC6	3	two hybrid, pull down, affinity chromatography technology	Romero F (1996), Romero F (1996), Romero F (1996)	3
EIF4E2	2	SH3PXD2A	4	affinity chromatography technology	Boldt K (2016)	1
RAD23A	1	TP53	0	affinity chromatography technology, affinity chromatography technology	Brignone C (2004), Hsieh HC (2005)	2
TP53	0	TP53BP1	3	x-ray crystallography, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology, x-ray crystallography, x-ray crystallography, two hybrid, pull down, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, unspecified method	Derbyshire DJ (2002), Sengupta S (2004), Sengupta S (2004), Ekblad CM (2004), Lo KW (2005), Joo WS (2002), Derbyshire DJ (2002), Iwabuchi K (1994), Iwabuchi K (1994), Iwabuchi K (1994), Roy S (2010), Dai C (2011), Tembe V (2015), Cuella-Martin R (2016), Cuella-Martin R (2016), Tong Q (2015), Tong Q (2015)	17
NFATC1	12	XRCC5	5	affinity chromatography technology	Gabriel CH (2016)	1
BCL2L14	2	CHEK1	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CUL1	7	PTBP1	2	affinity chromatography technology	Bennett EJ (2010)	1
FUS	0	CDC5L	2	affinity chromatography technology, affinity chromatography technology	Wang T (2014), Lleres D (2010)	2
CUL1	7	FUS	0	affinity chromatography technology	Bennett EJ (2010)	1
CASP8	1	CDK9	3	genetic interference	Shen JP (2017)	1
PCNA	0	RAD23A	1	biochemical	Kristensen AR (2012)	1
BRCA1	7	CDK9	3	two hybrid	Woods NT (2012)	1
MAPK1	1	MAPKAPK2	1	affinity chromatography technology, protein complementation assay, enzymatic study, affinity chromatography technology	Yannoni YM (2004), Srivastav RK (2011), Powell DW (2003), Krump E (1997)	4
CDKN1A	1	PCNA	0	two hybrid, pull down, pull down, pull down, pull down, x-ray crystallography, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, unspecified method, affinity chromatography technology, biochemical, two hybrid, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Rual JF (2005), Frouin I (2003), Watanabe H (1998), Fotedar R (1996), Jonsson ZO (1998), Gulbis JM (1996), Touitou R (2001), Yu P (2001), Yu P (2001), Chen X (2007), Chen X (2007), Wang SC (2006), Carujo S (2006), Garcia-Wilson E (2005), Howlett NG (2009), Jin Y (2008), Lee JY (2009), Ando T (2001), Ando T (2001), Takasaki Y (2001), Logette E (2011), Mistafa O (2010), Mistafa O (2010), Bruning JB (2004), Punchihewa C (2012), Mattock H (2001), Waga S (1994), Waga S (1994), Poon RY (1996), Zhang Y (1999), Warbrick E (1995), Warbrick E (1995), Poon RY (1998), Poon RY (1998), Wang J (2011), Fogeron ML (2013), Rolland T (2014), Rizzardi LF (2014), Trombetta A (2013), Trombetta A (2013), Kim DH (2010), Huttlin EL (2015), Hein MY (2015), Hein MY (2015), Coleman KE (2015), Huttlin EL (2017), Roessig L (2001), Roessig L (2001)	48
BRCA1	7	NBN	1	biochemical, biochemical, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wang Y (2000), Chiba N (2001), Zhong Q (1999), Shimada M (2009), Chen L (2008), Hill SJ (2014), Goldstein M (2015), Goldstein M (2015), Parameswaran B (2015)	9
HSP90AA1	7	KSR1	0	affinity chromatography technology	Taipale M (2012)	1
CDC25C	0	KCTD3	2	affinity chromatography technology	Boldt K (2016)	1
RB1	2	TP53	0	affinity chromatography technology, pull down	Delston RB (2011), Sommer MH (1994)	2
TOP2A	2	RAD17	2	genetic interference	Srivas R (2016)	1
FZR1	1	MCPH1	4	affinity chromatography technology, affinity chromatography technology	Liu X (2017), Liu X (2017)	2
UNC5CL	5	RELA	1	affinity chromatography technology	Zhang J (2004)	1
XRCC5	5	MSH2	4	biochemical	Kristensen AR (2012)	1
CSNK2A1	15	XRCC6	3	enzymatic study	Olsen BB (2010)	1
LATS2	1	TNRC6B	10	bioid	Couzens AL (2013)	1
ATR	6	RAD17	2	unspecified method, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology	Kim ST (1999), Bao S (2001), Bao S (2001), Bomgarden RD (2004), Zhang L (2010)	5
FANCD2	3	FANCE	6	two hybrid, two hybrid, two hybrid, biochemical, affinity chromatography technology, two hybrid, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Hussain S (2004), Gordon SM (2003), Pace P (2002), Pace P (2002), Howlett NG (2009), Nookala RK (2007), Leveille F (2006), Gordon SM (2005), Gordon SM (2005), Gordon SM (2005), Polito D (2014), Polito D (2014), Bouffard F (2015), Huard CC (2013), Huard CC (2013)	15
MAPKAPK2	1	CHEK1	2	genetic interference	Reinhardt HC (2010)	1
NFATC2	1	ARID1A	16	affinity chromatography technology	Gabriel CH (2016)	1
CDKN1A	1	ATXN3	2	two hybrid	Vinayagam A (2011)	1
WEE1	2	MTOR	14	genetic interference	Srivas R (2016)	1
VCP	6	MAPK1	1	affinity chromatography technology	Yu CC (2013)	1
BRD4	8	SMARCA4	19	affinity chromatography technology	Rahman S (2011)	1
USP11	3	XRCC5	5	affinity chromatography technology	Zhou Z (2017)	1
CHEK1	2	CDKN1A	1	affinity chromatography technology	Tian H (2002)	1
BRCA1	7	CDC25C	0	enzymatic study	Shabbeer S (2013)	1
CSNK2A1	15	TP53	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, enzymatic study	Uhle S (2003), Fogeron ML (2013), Bhansali M (2014), Chen TC (2014), Walerych D (2004), Walerych D (2004)	6
SNW1	0	CHEK1	2	affinity chromatography technology	Lleres D (2010)	1
SH3PXD2A	4	DENND1A	2	affinity chromatography technology	Boldt K (2016)	1
ATM	9	RELA	1	imaging technique	Fang L (2014)	1
PRKDC	12	AKT1	1	enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, genetic interference	Feng J (2004), Feng J (2004), Feng J (2004), Dragoi AM (2005), Dragoi AM (2005), Dragoi AM (2005), Shen JP (2017)	7
CHEK1	2	CLSPN	1	pull down, affinity chromatography technology, pull down, enzymatic study, pull down, affinity chromatography technology, pull down, affinity chromatography technology	Chini CC (2003), Chini CC (2003), Chini CC (2006), Chini CC (2006), Chini CC (2006), Huh J (2013), Clarke CA (2005), Clarke CA (2005)	8
FBXO6	0	IGF1R	5	affinity chromatography technology	Liu B (2012)	1
CDC5L	2	TOP2A	2	affinity chromatography technology, biochemical, affinity chromatography technology	Ajuh P (2000), Ajuh P (2000), Lleres D (2010)	3
CHEK2	2	CDC25C	0	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Eymin B (2006), Xu X (2002), Yang S (2002), Zannini L (2003), Buscemi G (2001), Zhou BB (2000), Magni M (2014), Wu X (2001), Fujimoto H (2006)	9
CDC73	1	RPS10	0	affinity chromatography technology	Herr P (2015)	1
BRCA1	7	PTBP1	2	affinity chromatography technology	Ertych N (2016)	1
MDM4	0	RB1	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Uchida C (2006), Uchida C (2006), Zhang H (2015), Zhang H (2015)	4
SNW1	0	CUL1	7	affinity chromatography technology	Lleres D (2010)	1
CDK9	3	CLSPN	1	affinity chromatography technology	Yu DS (2010)	1
TP53	0	SMARCA4	19	pull down, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lee D (2002), Lee D (2002), Lee D (2002), Napolitano MA (2007), Guan B (2011), Oh J (2008)	6
VCP	6	TP53BP1	3	affinity chromatography technology	Yu CC (2013)	1
TOP1	1	TTN	102	genetic interference	Srivas R (2016)	1
CUL1	7	TNRC6B	10	affinity chromatography technology	Bennett EJ (2010)	1
SNW1	0	ATM	9	affinity chromatography technology	Lleres D (2010)	1
PPM1A	1	CHEK1	2	biochemical	Wan C (2015)	1
CLSPN	1	TIMELESS	8	affinity chromatography technology	Yang XH (2008)	1
DTL	0	MSH6	2	affinity chromatography technology	Jascur T (2011)	1
RAD23A	1	UBA1	1	affinity chromatography technology, affinity chromatography technology	Chen L (2006), Chen L (2006)	2
CDK1	0	CHEK1	2	affinity chromatography technology	Hein MY (2015)	1
HNRNPD	3	USP11	3	affinity chromatography technology	Hein MY (2015)	1
GIGYF1	15	EIF4E2	2	far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Morita M (2012), Morita M (2012), Huttlin EL (2017), Boldt K (2016)	4
COPS5	0	TTN	102	affinity chromatography technology	Bennett EJ (2010)	1
CHEK2	2	BRCA1	7	pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, imaging technique	Lee JS (2000), Lee JS (2000), Chabalier-Taste C (2008), Chabalier-Taste C (2008), Liu Y (2002), Inoue Y (2007), Dutta D (2015), Dutta D (2015)	8
NBN	1	MSH2	4	biochemical	Wang Y (2000)	1
23380	0	LRFN1	4	affinity chromatography technology	Boldt K (2016)	1
PARP1	3	XRCC6	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, enzymatic study, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Ju BG (2006), Galande S (1999), Galande S (1999), Galande S (1999), Idogawa M (2007), Li B (2004), Li B (2004), Yin H (2006), Yin H (2006), Wu T (2013), Huttlin EL (2017)	11
BRD4	8	CDK9	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference	Jang MK (2005), Jang MK (2005), He N (2006), Yang Z (2008), Jeronimo C (2007), Zippo A (2009), Rahman S (2011), Bisgrove DA (2007), Bisgrove DA (2007), Yang Z (2005), Yang Z (2005), Lu H (2014), Srivas R (2016)	13
CDC25A	2	CUL1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jin J (2003), Donzelli M (2004), Busino L (2003), Donzelli M (2002), He N (2005), Li X (2016)	6
CDK1	0	CDKN1A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Amador V (2007), Ando T (2001), Lin ML (2011), Varjosalo M (2013), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	7
CHEK1	2	WRN	6	genetic interference	Srivas R (2016)	1
TP53BP1	3	XRCC5	5	affinity chromatography technology	Woods NT (2012)	1
NBN	1	MSH6	2	biochemical	Wang Y (2000)	1
HNRNPD	3	MTOR	14	affinity chromatography technology	Hein MY (2015)	1
BRCA1	7	DNMT1	5	affinity chromatography technology	Hill SJ (2014)	1
SRC	2	MET	7	affinity chromatography technology	Rahimi N (1998)	1
EIF4E2	2	LRFN1	4	affinity chromatography technology	Boldt K (2016)	1
TUBA1A	13	CHEK1	2	genetic interference	Srivas R (2016)	1
COPS5	0	PTBP1	2	affinity chromatography technology	Bennett EJ (2010)	1
TP53	0	PCNA	0	affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Banks D (2006), Banks D (2006), Hampp S (2016), Hampp S (2016)	4
EIF4E2	2	KIF13B	13	affinity chromatography technology	Boldt K (2016)	1
RELA	1	MEN1	1	pull down, affinity chromatography technology	Heppner C (2001), Heppner C (2001)	2
CDC5L	2	CDK9	3	affinity chromatography technology	Lleres D (2010)	1
VCP	6	CHEK2	2	affinity chromatography technology	Matsuoka S (2007)	1
XPO1	8	ERCC6L	3	affinity chromatography technology	Kirli K (2015)	1
MAP2K1	8	ATAD5	5	genetic interference	Srivas R (2016)	1
NFATC2	1	PARP1	3	affinity chromatography technology	Gabriel CH (2016)	1
RFC1	1	TP53	0	affinity chromatography technology	Anderson LA (2003)	1
HNRNPD	3	PTBP1	2	biochemical, two hybrid, two hybrid, biochemical, biochemical	Havugimana PC (2012), Hegele A (2012), Hegele A (2012), Kristensen AR (2012), Wan C (2015)	5
NFATC1	12	CHEK1	2	affinity chromatography technology, affinity chromatography technology	Gabriel CH (2016), Gabriel CH (2016)	2
WEE1	2	TTN	102	genetic interference	Srivas R (2016)	1
CSNK2A1	15	APP	1	pull down	Olah J (2011)	1
CDC25C	0	PCNA	0	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology	Kawabe T (2002), Kawabe T (2002), Kawabe T (2002), Ando T (2001)	4
XPO1	8	MAPKAPK2	1	affinity chromatography technology	Kirli K (2015)	1
CDC73	1	VCP	6	affinity chromatography technology	Herr P (2015)	1
FBXO6	0	SMARCA4	19	affinity chromatography technology	Liu B (2012)	1
AKT1	1	VHL	0	affinity chromatography technology, affinity chromatography technology, pull down, pull down, unspecified method	Guo J (2016), Guo J (2016), Guo J (2016), Guo J (2016), Guo J (2016)	5
AKT1	1	FANCD2	3	affinity chromatography technology	Zhang X (2016)	1
BRCA1	7	MSH6	2	two hybrid, pull down, biochemical, affinity chromatography technology	Wang Q (2001), Wang Q (2001), Wang Y (2000), Hill SJ (2014)	4
TOP2A	2	LLGL1	9	genetic interference	Srivas R (2016)	1
SFN	1	RACGAP1	2	affinity chromatography technology	Benzinger A (2005)	1
DNMT1	5	RB1	2	biochemical, pull down, affinity chromatography technology, pull down, affinity chromatography technology	Robertson KD (2000), Robertson KD (2000), Robertson KD (2000), Pradhan S (2002), Pradhan S (2002)	5
CHEK1	2	23380	0	affinity chromatography technology	Boldt K (2016)	1
BRCA1	7	USP7	14	affinity chromatography technology, affinity chromatography technology	Hill SJ (2014), Ertych N (2016)	2
TOP1	1	PARP1	3	affinity chromatography technology, fluorescent resonance energy transfe, affinity chromatography technology, pull down, biochemical	Czubaty A (2005), Yung TM (2004), Yung TM (2004), Yung TM (2004), Yung TM (2004)	5
CHEK2	2	TP53BP1	3	affinity chromatography technology	Matsuoka S (2007)	1
CDC5L	2	PARP1	3	affinity chromatography technology	Lleres D (2010)	1
CHEK1	2	POLA1	0	affinity chromatography technology	Taricani L (2009)	1
DDB1	6	UBA1	1	affinity chromatography technology, affinity chromatography technology	Panigrahi AK (2011), Panigrahi AK (2011)	2
EIF4E2	2	TARS	2	affinity chromatography technology	Huttlin EL (2017)	1
MSH2	4	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zink D (2002), Zink D (2002), Yang Q (2004)	3
TCEA1	0	CDC73	1	pull down	Kim J (2010)	1
KSR1	0	GIGYF1	15	affinity chromatography technology	Boldt K (2016)	1
SH3PXD2A	4	GIGYF1	15	affinity chromatography technology	Boldt K (2016)	1
BLM	2	CASP8	1	affinity chromatography technology	Hein MY (2015)	1
RAD51	3	MSH2	4	affinity chromatography technology	Yang Q (2004)	1
CHEK1	2	VEGFA	3	genetic interference	Shen JP (2017)	1
PARP1	3	PRKDC	12	affinity chromatography technology	Ju BG (2006)	1
ATXN3	2	XRCC6	3	affinity chromatography technology	Li Y (2007)	1
CASP8	1	CHEK1	2	genetic interference	Shen JP (2017)	1
IL13RA2	0	CHEK1	2	affinity chromatography technology	Huttlin EL (2017)	1
SH3PXD2A	4	CHEK1	2	affinity chromatography technology	Boldt K (2016)	1
KSR1	0	KIF13B	13	affinity chromatography technology	Boldt K (2016)	1
RELA	1	USP7	14	affinity chromatography technology, affinity chromatography technology, enzymatic study	Colleran A (2013), Colleran A (2013), Colleran A (2013)	3
CHEK1	2	DTL	0	affinity chromatography technology, enzymatic study, enzymatic study	Huh J (2013), Cheng YC (2013), Huh J (2013)	3
VCP	6	MAP2K1	8	affinity chromatography technology	Yu CC (2013)	1
CDC5L	2	RACGAP1	2	affinity chromatography technology	Lleres D (2010)	1
KCTD3	2	GIGYF1	15	affinity chromatography technology	Boldt K (2016)	1
CDK9	3	PIK3CA	8	genetic interference	Shen JP (2017)	1
TUBA1A	13	ATXN3	2	pull down	Bonanomi M (2014)	1
DHFR	0	WEE1	2	genetic interference	Srivas R (2016)	1
KSR1	0	EIF4E2	2	affinity chromatography technology	Boldt K (2016)	1
CDKN1A	1	APP	1	pull down	Olah J (2011)	1
CHEK1	2	VHL	0	genetic interference	Shen JP (2017)	1
TIMELESS	8	PCNA	0	affinity chromatography technology	Yang XH (2008)	1
SNW1	0	HNRNPD	3	affinity chromatography technology	Lleres D (2010)	1
CDC6	0	ATM	9	pull down	Yoshida K (2010)	1
AKT1	1	APP	1	pull down	Olah J (2011)	1
LRFN1	4	KIF13B	13	affinity chromatography technology	Boldt K (2016)	1
COPS5	0	HSP90AA1	7	affinity chromatography technology	Bennett EJ (2010)	1
CASP8	1	MTOR	14	genetic interference	Shen JP (2017)	1
IGF1R	5	PPM1A	1	affinity chromatography technology, two hybrid	Yao Z (2017), Yao Z (2017)	2
AKT1	1	BCL2L1	0	enzymatic study	Qi XJ (2006)	1
CHEK2	2	LLGL1	9	genetic interference	Srivas R (2016)	1
BRCA1	7	TOP1	1	genetic interference, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study	Shen JP (2017), Ando K (2017), Ando K (2017), Ando K (2017), Ando K (2017), Ando K (2017), Ando K (2017)	7
CHEK1	2	WEE1	2	genetic interference, genetic interference	Srivas R (2016), Srivas R (2016)	2
ZEB1	3	CHEK1	2	affinity chromatography technology	Zhang P (2014)	1
BRCA1	7	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, biochemical, pull down, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Abramovitch S (2004), Ouchi T (1998), Dong Y (2003), Dong Y (2003), Chai YL (1999), Chai YL (1999), Zhang H (1998), Dong Y (2003), Chen Y (2006), Quaresima B (2006), Zhang H (1998), Zhang H (1998), Mark WY (2005), Jin S (2009), Jiang J (2011), Rasti M (2015), Rasti M (2015)	17
XRCC5	5	ATR	6	pull down, affinity chromatography technology	Falck J (2005), Falck J (2005)	2
CDC5L	2	MSH2	4	affinity chromatography technology	Lleres D (2010)	1
CHEK1	2	CDC73	1	genetic interference	Srivas R (2016)	1
CHEK1	2	DNMT1	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Palii SS (2008), Palii SS (2008), Ha K (2011)	3
HNRNPD	3	FANCD2	3	affinity chromatography technology	Hein MY (2015)	1
MEN1	1	FANCD2	3	affinity chromatography technology, pull down	Jin S (2003), Jin S (2003)	2
CHEK1	2	CDC25B	4	enzymatic study, pull down	Sanchez Y (1997), Sanchez Y (1997)	2
TOP3A	0	CDC73	1	genetic interference	Srivas R (2016)	1
CDC73	1	SFN	1	affinity chromatography technology	Herr P (2015)	1
VHL	0	HNRNPD	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, pull down	Lai Y (2011), Xin H (2011), Xin H (2011), Xin H (2011), Xin H (2011), Xin H (2011)	6
SNW1	0	LDLRAP1	0	affinity chromatography technology	Lleres D (2010)	1
CHEK1	2	MTOR	14	genetic interference, genetic interference, genetic interference	Shen JP (2017), Srivas R (2016), Srivas R (2016)	3
CDC25C	0	KIF13B	13	affinity chromatography technology	Boldt K (2016)	1
MAPK1	1	CHEK2	2	biochemical	Wan C (2015)	1
LRFN1	4	GIGYF1	15	affinity chromatography technology	Boldt K (2016)	1
CDC5L	2	ARID1A	16	affinity chromatography technology	Lleres D (2010)	1
FZR1	1	TP53	0	enzymatic study	Gmachl M (2000)	1
CDC73	1	UBA1	1	affinity chromatography technology	Herr P (2015)	1
TP53	0	TOP2A	2	affinity chromatography technology, pull down, genetic interference	Cowell IG (2000), Cowell IG (2000), Xie L (2013)	3
CUL4A	2	FUS	0	affinity chromatography technology	Bennett EJ (2010)	1
WRN	6	NBN	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Cheng WH (2005), Kobayashi J (2010), Kobayashi J (2010)	3
BRCA1	7	TOP2A	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Lou Z (2005), Lou Z (2005), Lou Z (2005), Hill SJ (2014)	4
COPS5	0	XRCC6	3	affinity chromatography technology	Bennett EJ (2010)	1
DHFR	0	CHEK1	2	genetic interference	Srivas R (2016)	1
CHEK1	2	KCTD3	2	affinity chromatography technology	Boldt K (2016)	1
UNC5CL	5	IGF1R	5	affinity chromatography technology	Huttlin EL (2017)	1
DTL	0	TP53	0	affinity chromatography technology, enzymatic study	Banks D (2006), Banks D (2006)	2
PLA2G10	0	CHEK1	2	affinity chromatography technology	Huttlin EL (2017)	1
MAPKAPK2	1	BCL2L1	0	enzymatic study	Wang J (2012)	1
CHEK2	2	DAAM1	3	genetic interference	Srivas R (2016)	1
TP53	0	FHIT	0	genetic interference	Xie L (2013)	1
WEE1	2	FZR1	1	genetic interference	Srivas R (2016)	1
NBN	1	RFC1	1	biochemical	Wang Y (2000)	1
CDK1	0	TP53	0	enzymatic study, affinity chromatography technology	Luciani MG (2000), Ababneh M (2001)	2
CUL1	7	AKT1	1	affinity chromatography technology	Reitsma JM (2017)	1
TOP2A	2	TTN	102	genetic interference	Srivas R (2016)	1
EIF4E2	2	CBY1	3	affinity chromatography technology	Boldt K (2016)	1
BRCA1	7	FUS	0	affinity chromatography technology	Ertych N (2016)	1
DNMT1	5	PARP1	3	affinity chromatography technology	Cai Y (2014)	1
CDC5L	2	MSH6	2	affinity chromatography technology	Lleres D (2010)	1
BRCA1	7	MTOR	14	affinity chromatography technology	Woods NT (2012)	1
CDC25C	0	SFN	1	affinity chromatography technology	Isagawa T (2005)	1
CDC5L	2	TOP1	1	affinity chromatography technology	Lleres D (2010)	1
CDK1	0	WEE1	2	enzymatic study	Watanabe N (2004)	1
CDK9	3	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mak AB (2010), Taipale M (2012), Varjosalo M (2013), Huttlin EL (2015), Huttlin EL (2017)	5
PCNA	0	MSH2	4	affinity chromatography technology, far western blotting	Ohta S (2002), Dzantiev L (2004)	2
WRN	6	CDC5L	2	affinity chromatography technology, affinity chromatography technology	Zhang N (2005), Zhang N (2005)	2
LRFN1	4	CBY1	3	affinity chromatography technology	Boldt K (2016)	1
COPS5	0	TNRC6B	10	affinity chromatography technology	Bennett EJ (2010)	1
NAT9	1	CHEK1	2	affinity chromatography technology	Huttlin EL (2017)	1
RAD23A	1	VCP	6	affinity chromatography technology	Laco MN (2012)	1
CHEK1	2	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Leung-Pineda V (2009), Leung-Pineda V (2009), Huh J (2013), Williamson EA (2014)	4
CUL4A	2	PCNA	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Angers S (2006), Lo YH (2012), Banks D (2006)	3
VHL	0	TUBA1A	13	affinity chromatography technology, affinity chromatography technology	Lai Y (2011), Hergovich A (2003)	2
HNRNPD	3	MSH2	4	biochemical	Havugimana PC (2012)	1
CHEK2	2	CDC14A	4	genetic interference	Srivas R (2016)	1
MET	7	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Jang KW (2011), Prince TL (2015)	2
TP53BP1	3	XRCC6	3	affinity chromatography technology	Woods NT (2012)	1
CHEK1	2	IGF1R	5	genetic interference	Shen JP (2017)	1
DDB1	6	DNMT1	5	pull down	Yang Y (2015)	1
FZR1	1	RACGAP1	2	affinity chromatography technology	Nishimura K (2013)	1
CHEK2	2	CUL4A	2	affinity chromatography technology	Huh J (2013)	1
USP7	14	CHEK1	2	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study	Qing P (2011), Zhang P (2014), Zhang P (2014), Tan X (2015), Alonso-de Vega I (2014)	5
RFC1	1	XRCC6	3	biochemical	Wan C (2015)	1
MAP2K1	8	TTN	102	genetic interference	Srivas R (2016)	1
MSH6	2	ATM	9	biochemical	Wang Y (2000)	1
AKT1	1	MTOR	14	pull down, unspecified method, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, imaging technique, enzymatic study, imaging technique	Sekulic A (2000), Cheng SW (2004), Oh WJ (2010), Sarbassov DD (2005), Ikenoue T (2008), Murata H (2011), Martin J (2008), Facchinetti V (2008), Facchinetti V (2008), Chen CH (2011), Xu Y (2013), Glidden EJ (2012), Chen TC (2014), Pitre A (2012), Moon HE (2015)	15
TOP2A	2	MSH2	4	genetic interference	Srivas R (2016)	1
WEE1	2	CSNK2A1	15	affinity chromatography technology, biochemical	Olsen BB (2008), Olsen BB (2008)	2
CHEK1	2	TYMS	0	genetic interference	Shen JP (2017)	1
PCNA	0	TOP1	1	affinity chromatography technology	Takasaki Y (2001)	1
VCP	6	TOP1	1	affinity chromatography technology	Yu CC (2013)	1
MAPKAPK2	1	CDC25B	4	enzymatic study	Manke IA (2005)	1
SETMAR	3	PCNA	0	affinity chromatography technology, affinity chromatography technology	De Haro LP (2010), De Haro LP (2010)	2
IGF1R	5	IL13RA2	0	two hybrid	Arroyo R (2015)	1
XRCC5	5	PPM1A	1	affinity chromatography technology	Hein MY (2015)	1
CHEK1	2	CUL4A	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Leung-Pineda V (2009), Liu S (2009), Huh J (2013), Zhang YW (2005)	4
SRC	2	MAPK1	1	affinity chromatography technology	Lee J (2013)	1
TUBA1A	13	MTOR	14	genetic interference	Srivas R (2016)	1
CDKN1A	1	TUBA1A	13	two hybrid, affinity chromatography technology	Vinayagam A (2011), Fogeron ML (2013)	2
CUL4A	2	CUL1	7	biochemical	He YJ (2006)	1
RPS10	0	XRCC6	3	two hybrid	Vinayagam A (2011)	1
TP53	0	TUBA1A	13	affinity chromatography technology	Fogeron ML (2013)	1
CDK9	3	CSNK2A1	15	affinity chromatography technology	Claudio PP (2006)	1
POLA1	0	UBA2	0	genetic interference	Horlbeck MA (2018)	1
HSP90AA1	7	SRC	2	affinity chromatography technology, affinity chromatography technology	Hutchison KA (1992), Tsutsumi S (2012)	2
CSNK2A1	15	MSH6	2	enzymatic study	Zhang M (2011)	1
HSP90AA1	7	LLGL1	9	genetic interference	Srivas R (2016)	1
TOP3A	0	CDC6	0	genetic interference	Srivas R (2016)	1
KSR1	0	23380	0	affinity chromatography technology	Boldt K (2016)	1
AKT1	1	VCP	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Vandermoere F (2006), Vandermoere F (2006), Vandermoere F (2006), Klein JB (2005), Klein JB (2005), Klein JB (2005), Yu CC (2013), Yu CC (2013)	8
PCNA	0	ATAD5	5	pull down, affinity chromatography technology, affinity chromatography technology	Lee KY (2010), Lee KY (2010), Hein MY (2015)	3
COPS5	0	KCTD3	2	affinity chromatography technology	Bennett EJ (2010)	1
FBXO6	0	PTBP1	2	affinity chromatography technology	Liu B (2012)	1
SH3PXD2A	4	KCTD3	2	affinity chromatography technology	Boldt K (2016)	1
WEE1	2	WRN	6	genetic interference	Srivas R (2016)	1
AKT1	1	MAPKAPK2	1	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, imaging technique	Rane MJ (2001), Rane MJ (2001), Rane MJ (2001), Rane MJ (2001), Wu R (2007), Wu R (2007), Chen TC (2014)	7
EIF4E2	2	CHEK1	2	affinity chromatography technology	Boldt K (2016)	1
ATXN3	2	APP	1	pull down	Olah J (2011)	1
NFATC2	1	RB1	2	affinity chromatography technology	Gabriel CH (2016)	1
BRD4	8	RFC1	1	affinity chromatography technology, affinity chromatography technology, pull down	Maruyama T (2002), Maruyama T (2002), Maruyama T (2002)	3
CLSPN	1	BRCA1	7	affinity chromatography technology, affinity chromatography technology, enzymatic study	Lin SY (2004), Lin SY (2004), Sato K (2012)	3
CHEK2	2	CDC25A	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down	Jin J (2008), Hassepass I (2003), Sorensen CS (2003), Falck J (2001), Falck J (2001)	5
CHEK1	2	PARP1	3	genetic interference	Shen JP (2017)	1
ATR	6	ATM	9	unspecified method, enzymatic study	Kim ST (1999), Stiff T (2006)	2
ATR	6	CHEK1	2	unspecified method, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, genetic interference	Kim ST (1999), Sun TP (2009), Zhao H (2001), Rocha S (2005), Choi JH (2007), Ha K (2011), Srivas R (2016)	7
PTBP1	2	CHEK1	2	biochemical	Wan C (2015)	1
WRN	6	XRCC6	3	affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Karmakar P (2002), Karmakar P (2002), Li B (2000), Cooper MP (2000), Cooper MP (2000), Cooper MP (2000), Li B (2004), Li B (2004), Hein MY (2015), Huttlin EL (2017)	10
ARID1A	16	CHEK1	2	genetic interference	Shen JP (2017)	1
TOP1	1	LLGL1	9	genetic interference	Srivas R (2016)	1
MAPK1	1	TTN	102	enzymatic study, genetic interference	Raskin A (2012), Srivas R (2016)	2
TOP2A	2	CHEK1	2	genetic interference	Srivas R (2016)	1
CDK1	0	POLA1	0	enzymatic study	Dehde S (2001)	1
RFC1	1	PCNA	0	affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, pull down, pull down, far western blotting, affinity chromatography technology, biochemical, affinity chromatography technology	Maruyama T (2002), Fotedar R (1996), Fotedar R (1996), Mossi R (1997), van der Kuip H (1999), Ohta S (2002), Ohta S (2002), Dahm K (2002), Havugimana PC (2012), Montecucco A (1998), Uhlmann F (1997), Dzantiev L (2004), Han J (2014), Wan C (2015), Hein MY (2015)	15
CHEK1	2	LLGL1	9	genetic interference	Srivas R (2016)	1
ATM	9	RFC1	1	biochemical	Wang Y (2000)	1
CDC25B	4	ZBTB21	2	affinity chromatography technology	Boldt K (2016)	1
CDK1	0	RB1	2	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Horton LE (1997), Lees JA (1991), Knudsen ES (1996), Jiang W (1998), De Luca A (1997), Chen Z (2002), Knudsen ES (1997), Pan W (2001)	8
KSR1	0	CBY1	3	affinity chromatography technology	Boldt K (2016)	1
XRCC5	5	VAV1	2	affinity chromatography technology	Adam L (2000)	1
ATM	9	NBN	1	unspecified method, biochemical, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kim ST (1999), Wang Y (2000), Cariveau MJ (2007), Falck J (2005), Falck J (2005), Falck J (2005), Falck J (2005), Falck J (2005), Falck J (2005), Wu J (2012), Wu J (2012), Wei F (2015)	12
CDC25B	4	KCTD3	2	affinity chromatography technology	Boldt K (2016)	1
CHEK1	2	XIAP	0	pull down, affinity chromatography technology, pull down	Galvan V (2004), Galvan V (2004), Galvan V (2004)	3
CHEK1	2	BRD4	8	genetic interference	Srivas R (2016)	1
CDC14A	4	FZR1	1	enzymatic study	Bembenek J (2001)	1
LATS2	1	SRC	2	affinity chromatography technology	Si Y (2017)	1
TOPBP1	5	DDB1	6	affinity chromatography technology	Wang J (2013)	1
CHEK1	2	KIF13B	13	affinity chromatography technology	Boldt K (2016)	1
SNW1	0	NBN	1	affinity chromatography technology	Lleres D (2010)	1
SRC	2	CSNK2A1	15	affinity chromatography technology	Liang K (2010)	1
FBXO6	0	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Liu B (2012), Taipale M (2012)	2
CHEK2	2	MDM4	0	enzymatic study	Chen L (2005)	1
KSR1	0	LRFN1	4	affinity chromatography technology	Boldt K (2016)	1
CSNK2A1	15	PTEN	24	enzymatic study, pull down, affinity chromatography technology, enzymatic study	Miller SJ (2002), Miller SJ (2002), Crockett DK (2005), Li Z (2014)	4
FANCD2	3	TOP3A	0	biochemical	Raghunandan M (2015)	1
MEPE	0	CHEK1	2	two hybrid, affinity chromatography technology, imaging technique, affinity chromatography technology	Liu S (2009), Liu S (2009), Liu S (2009), Liu S (2009)	4
TOP2A	2	CDC6	0	genetic interference	Srivas R (2016)	1
COPS5	0	CHEK1	2	affinity chromatography technology	Bennett EJ (2010)	1
BRCA1	7	TNRC6B	10	affinity chromatography technology	Ertych N (2016)	1
CHEK1	2	XRCC6	3	affinity chromatography technology, affinity chromatography technology	Goudelock DM (2003), Goudelock DM (2003)	2
ATM	9	TP53	0	pull down, pull down, pull down, genetic interference, unspecified method, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, imaging technique	Kang J (2005), Fabbro M (2004), Khanna KK (1998), Westphal CH (1997), Kim ST (1999), Khanna KK (1998), Lee JH (2004), Lee JH (2004), Hunt CR (2007), Lin WC (2001), Ling S (2011), Taira N (2010), Lee JH (2005), Zhou BB (2000), Chan DW (2000), Yoshiyama KO (2013), Kim ST (1999), Zhang P (2014), Wang L (2014), Golding SE (2004), Ochodnicka-Mackovicova K (2016)	21
CHEK2	2	BLM	2	genetic interference	Srivas R (2016)	1
ZBTB21	2	LRFN1	4	affinity chromatography technology	Boldt K (2016)	1
CHEK2	2	RFC1	1	genetic interference	Srivas R (2016)	1
WRN	6	PARP1	3	affinity chromatography technology, pull down, affinity chromatography technology	Li B (2004), Li B (2004), Li B (2004)	3
CDC25B	4	23380	0	affinity chromatography technology	Boldt K (2016)	1
WRN	6	TP53	0	affinity chromatography technology, pull down, pull down	Yang Q (2002), Yang Q (2002), Brosh RM (2001)	3
COPS5	0	HNRNPD	3	affinity chromatography technology	Bennett EJ (2010)	1
SNW1	0	BLM	2	affinity chromatography technology	Lleres D (2010)	1
XPO1	8	NEK9	1	affinity chromatography technology	Kirli K (2015)	1
CHEK1	2	CDC25C	0	enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Sanchez Y (1997), Sanchez Y (1997), Olson E (2006), Eymin B (2006), Maude SL (2005), Yarden RI (2002), Chen J (2000), Sun TP (2009), Zhao H (2001), Groth A (2003), Graves PR (2000), Arlander SJ (2006)	12
FANCD2	3	PARP1	3	genetic interference	Ward TA (2017)	1
TP53	0	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
ATXN3	2	RAD23A	1	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Wang G (2000), Wang G (2000), Wang G (2000), Scanlon TC (2009), Lim J (2006), Laco MN (2012), Laco MN (2012), Ferro A (2007), Chen L (2006)	9
KCTD3	2	KIF13B	13	affinity chromatography technology	Boldt K (2016)	1
CDKN1A	1	DTL	0	affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study	Abbas T (2008), Abbas T (2008), Nishitani H (2008), Kim DH (2010), Zhang L (2012), Abbas T (2008), Shibata E (2011)	7
DENND1A	2	GIGYF1	15	affinity chromatography technology	Boldt K (2016)	1
CDC25C	0	GIGYF1	15	affinity chromatography technology	Boldt K (2016)	1
DENND1A	2	CDC25C	0	affinity chromatography technology	Boldt K (2016)	1
23380	0	GIGYF1	15	affinity chromatography technology	Boldt K (2016)	1
MSH6	2	PRKDC	12	affinity chromatography technology	Shahi A (2011)	1
CHEK1	2	MDM4	0	enzymatic study, enzymatic study	Jin Y (2006), Chen L (2005)	2
HSP90AA1	7	RB1	2	genetic interference	Srivas R (2016)	1
XPO1	8	MTOR	14	affinity chromatography technology	Kirli K (2015)	1
HLA-DRB5	4	CHEK1	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
IMPDH1	2	CDC73	1	genetic interference	Srivas R (2016)	1
MCPH1	4	ATR	6	imaging technique	Rai R (2006)	1
XRCC5	5	POLA1	0	affinity chromatography technology	Matheos D (2002)	1
CDK9	3	PRKDC	12	genetic interference	Shen JP (2017)	1
CHEK2	2	CDC73	1	genetic interference	Srivas R (2016)	1
CHEK2	2	RB1	2	enzymatic study, pull down, affinity chromatography technology	Inoue Y (2007), Inoue Y (2007), Inoue Y (2007)	3
SNW1	0	CDK9	3	affinity chromatography technology, affinity chromatography technology	Bres V (2009), Lleres D (2010)	2
TP53	0	LATS2	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
IL13RA2	0	LRFN1	4	affinity chromatography technology	Huttlin EL (2017)	1
POLA1	0	RB1	2	affinity chromatography technology, biochemical	Takemura M (1997), Takemura M (1997)	2
PIK3CA	8	AKT1	1	affinity chromatography technology, protein complementation assay, affinity chromatography technology, enzymatic study	Mitra S (2011), Miao B (2010), Xiong Y (2009), Akil H (2015)	4
CSNK2A1	15	ATAD5	5	genetic interference	Srivas R (2016)	1
CDC25B	4	CUL1	7	affinity chromatography technology	Li X (2016)	1
CUL1	7	PCNA	0	affinity chromatography technology	Bennett EJ (2010)	1
MSH6	2	ATR	6	affinity chromatography technology, affinity chromatography technology	Liu Y (2010), Liu Y (2010)	2
RAD51	3	TUBA1A	13	biochemical	Skvarova Kramarzova K (2017)	1
CDKN1A	1	DDB1	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Abbas T (2008), Abbas T (2008), Nishitani H (2008), Fogeron ML (2013)	4
PTEN	24	HSP90AA1	7	affinity chromatography technology, genetic interference	Maddika S (2011), Shen JP (2017)	2
BLM	2	XIAP	0	genetic interference	Vizeacoumar FJ (2013)	1
TP53	0	SNW1	0	affinity chromatography technology	Fogeron ML (2013)	1
CDC6	0	ATR	6	pull down, affinity chromatography technology	Yoshida K (2010), Yoshida K (2010)	2
ATXN3	2	BCL2L1	0	affinity chromatography technology, affinity chromatography technology	Zhou L (2013), Zhou L (2013)	2
TOPBP1	5	CHEK1	2	enzymatic study	Choi JH (2007)	1
ATM	9	COPS5	0	enzymatic study	Nagarajan A (2014)	1
BRCA1	7	WEE1	2	genetic interference	Shen JP (2017)	1
CASP8	1	TP53	0	affinity chromatography technology, affinity chromatography technology	Yao Z (2007), Yao Z (2007)	2
CHEK2	2	TTN	102	genetic interference	Srivas R (2016)	1
MSH6	2	CLSPN	1	affinity chromatography technology, affinity chromatography technology	Liu Y (2010), Liu Y (2010)	2
CHEK1	2	GIGYF1	15	affinity chromatography technology	Boldt K (2016)	1
NBN	1	MTOR	14	affinity chromatography technology, affinity chromatography technology	Wang JQ (2013), Wang JQ (2013)	2
HSP90AA1	7	CSNK2A1	15	pull down, enzymatic study, enzymatic study, affinity chromatography technology	Miyata Y (1995), Muller P (2012), Zhang M (2011), Woo SH (2009)	4
CUL4A	2	HNRNPD	3	affinity chromatography technology	Bennett EJ (2010)	1
BRCA1	7	XRCC6	3	affinity chromatography technology, affinity chromatography technology	Woods NT (2012), Ertych N (2016)	2
COPS5	0	RPS10	0	affinity chromatography technology	Bennett EJ (2010)	1
CDC25B	4	CDC5L	2	affinity chromatography technology	Hein MY (2015)	1
ATM	9	CHEK2	2	enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Lee JH (2004), Lee JH (2004), Matsuoka S (2000), Lee JH (2005), Zhou BB (2000), Chan DW (2000)	6
CASP8	1	VHL	0	genetic interference	Shen JP (2017)	1
FBXO6	0	VCP	6	affinity chromatography technology, affinity chromatography technology	Yoshida Y (2005), Yoshida Y (2005)	2
MET	7	PTEN	24	genetic interference	Shen JP (2017)	1
VCP	6	CDKN1A	1	affinity chromatography technology	Yu CC (2013)	1
MSH2	4	RFC1	1	biochemical	Wang Y (2000)	1
SFN	1	MDM4	0	affinity chromatography technology	LeBron C (2006)	1
RAD51	3	TP53	0	affinity chromatography technology, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Dong Y (2003), Dong Y (2003), Dong Y (2003), Stuerzbecher HW (1996), Stuerzbecher HW (1996), Buchhop S (1997), Nakai-Murakami C (2007), Yang Q (2004), Rasti M (2015), Rasti M (2015)	10
CDK9	3	RELA	1	pull down, affinity chromatography technology	Amini S (2002), Amini S (2002)	2
CDC25B	4	DENND1A	2	affinity chromatography technology	Boldt K (2016)	1
MCPH1	4	SMARCC1	5	affinity chromatography technology, affinity chromatography technology	Peng G (2009), Peng G (2009)	2
CDC25C	0	CBY1	3	affinity chromatography technology	Boldt K (2016)	1
ILKAP	2	CDK9	3	biochemical	Wan C (2015)	1
TOPBP1	5	NBN	1	affinity chromatography technology, affinity chromatography technology	Morishima K (2007), Morishima K (2007)	2
DHFR	0	TP53	0	pull down	Maguire M (2008)	1
PTEN	24	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Freeman DJ (2003), Freeman DJ (2003), Zhou M (2003), Zhou M (2003), Hong SW (2013), Li Y (2008)	6
ATM	9	PARP1	3	pull down	Haince JF (2007)	1
TOP1	1	APP	1	pull down	Olah J (2011)	1
CHEK1	2	SMO	0	genetic interference	Shen JP (2017)	1
MSH6	2	RFC1	1	biochemical	Wang Y (2000)	1
BLM	2	TOP2A	2	affinity chromatography technology, affinity chromatography technology	Bhattacharyya S (2009), Bhattacharyya S (2009)	2
XPO1	8	CSNK2A1	15	affinity chromatography technology	Kirli K (2015)	1
SNW1	0	FUS	0	affinity chromatography technology	Lleres D (2010)	1
SNW1	0	ATR	6	affinity chromatography technology	Lleres D (2010)	1
HSP90AA1	7	CDKN1A	1	affinity chromatography technology	Jascur T (2005)	1
ATM	9	RAD17	2	unspecified method, affinity chromatography technology, affinity chromatography technology	Kim ST (1999), Bao S (2001), Tsai WB (2008)	3
FANCD2	3	MSH2	4	affinity chromatography technology, genetic interference	Williams SA (2011), Peng M (2014)	2
TOP1	1	CDC73	1	genetic interference	Srivas R (2016)	1
SH3PXD2A	4	LRFN1	4	affinity chromatography technology	Boldt K (2016)	1
BRCA1	7	AKT1	1	pull down, affinity chromatography technology, pull down, enzymatic study, pull down	Altiok S (1999), Xiang T (2008), Xiang T (2008), Xiang T (2008), Xiang T (2011)	5
ATR	6	CHEK2	2	enzymatic study, enzymatic study, genetic interference	Olson E (2006), Matsuoka S (2000), Srivas R (2016)	3
SNW1	0	ARID1A	16	affinity chromatography technology	Lleres D (2010)	1
FUS	0	TARS	2	biochemical	Wan C (2015)	1
CDC25A	2	APP	1	pull down	Olah J (2011)	1
RAD51	3	ATM	9	affinity chromatography technology, affinity chromatography technology	Chen G (1999), Chen G (1999)	2
CBY1	3	KIF13B	13	affinity chromatography technology	Boldt K (2016)	1
CHEK1	2	APP	1	pull down	Olah J (2011)	1
RELA	1	IGF1R	5	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CDC5L	2	NBN	1	affinity chromatography technology	Lleres D (2010)	1
TUBA1A	13	TTN	102	genetic interference	Srivas R (2016)	1
ATM	9	BLM	2	biochemical, pull down, affinity chromatography technology	Wang Y (2000), Beamish H (2002), Beamish H (2002)	3
PTEN	24	XIAP	0	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Van Themsche C (2009), Van Themsche C (2009), Van Themsche C (2009), Ahmed SF (2012)	4
CHEK1	2	MCPH1	4	pull down	Alderton GK (2006)	1
VAV1	2	MAP2K1	8	affinity chromatography technology	Song JS (1996)	1
23380	0	ZBTB21	2	affinity chromatography technology	Boldt K (2016)	1
PTEN	24	TUBA1A	13	genetic interference	Vizeacoumar FJ (2013)	1
CHEK1	2	ZBTB21	2	affinity chromatography technology	Boldt K (2016)	1
SNW1	0	CDC73	1	affinity chromatography technology	Lleres D (2010)	1
RELA	1	PRKDC	12	affinity chromatography technology	Veena MS (2014)	1
RAD51	3	BLM	2	affinity chromatography technology, two hybrid, far western blotting, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference	Wu L (2001), Wu L (2001), Wu L (2001), Yang Q (2004), Srivastava V (2009), Ayguen O (2008), Vizeacoumar FJ (2013)	7
USP11	3	XIAP	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Zhou Z (2017), Zhou Z (2017), Zhou Z (2017)	4
PIK3CA	8	IL13RA2	0	two hybrid	Arroyo R (2015)	1
CHEK1	2	RAD51	3	affinity chromatography technology, affinity chromatography technology	Sorensen CS (2005), Sorensen CS (2005)	2
NFATC1	12	SMARCC1	5	affinity chromatography technology	Gabriel CH (2016)	1
ATR	6	BRCA1	7	pull down, unspecified method, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Tibbetts RS (2000), Kim ST (1999), Mu JJ (2007), Chen J (2000), Chen J (2000), Tibbetts RS (2000), Gatei M (2001), Gatei M (2001), Gatei M (2001), Tian F (2013)	10
CHEK1	2	CSNK2A1	15	pull down, affinity chromatography technology	Kristensen LP (2004), Guerra B (2003)	2
CDC6	0	POLA1	0	biochemical	Wan C (2015)	1
BRCA1	7	CDC5L	2	affinity chromatography technology	Ertych N (2016)	1
TOP3A	0	LLGL1	9	genetic interference	Srivas R (2016)	1
TP53	0	ARID1A	16	affinity chromatography technology, pull down	Guan B (2011), Guan B (2011)	2
CUL1	7	CDC5L	2	affinity chromatography technology, affinity chromatography technology	Bennett EJ (2010), Lleres D (2010)	2
CDC25A	2	VCP	6	affinity chromatography technology	Riemer A (2014)	1
COPS5	0	APP	1	pull down, affinity chromatography technology	Olah J (2011), Wang H (2013)	2
RB1	2	SMARCA4	19	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Dunaief JL (1994), Reyes JC (1997), Qiu Z (2008), Dasgupta P (2004), Zhang HS (2000), Zhang HS (2000), Napolitano MA (2007), Dunaief JL (2002), Tu Z (2013)	9
ILKAP	2	CHEK2	2	biochemical	Wan C (2015)	1
SNW1	0	MEN1	1	affinity chromatography technology, affinity chromatography technology, pull down	Bres V (2009), Bres V (2009), Bres V (2009)	3
MAP2K1	8	VHL	0	genetic interference	Shen JP (2017)	1
BLM	2	ATR	6	affinity chromatography technology, affinity chromatography technology, enzymatic study	Davies SL (2004), Davies SL (2004), Davies SL (2004)	3
RFC1	1	RELA	1	affinity chromatography technology, pull down, affinity chromatography technology	Anderson LA (2003), Anderson LA (2003), Anderson LA (2003)	3
COPS5	0	MAPKAPK2	1	affinity chromatography technology	Bennett EJ (2010)	1
CASP8	1	PARP1	3	enzymatic study	Betin VM (2009)	1
CHEK1	2	SMARCA4	19	genetic interference	Shen JP (2017)	1
PTBP1	2	FUS	0	biochemical	Wan C (2015)	1
FZR1	1	CLSPN	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Gao D (2009), Bassermann F (2008), Bassermann F (2008)	3
EIF4E2	2	ZBTB21	2	affinity chromatography technology	Boldt K (2016)	1
PCNA	0	CDC6	0	two hybrid	Saha P (1998)	1
BRCA1	7	SMARCA4	19	affinity chromatography technology, pull down, biochemical, pull down, affinity chromatography technology, affinity chromatography technology	Hill DA (2004), Bochar DA (2000), Bochar DA (2000), Bochar DA (2000), Tu Z (2013), Ertych N (2016)	6
NFATC2	1	XRCC5	5	affinity chromatography technology	Gabriel CH (2016)	1
CHEK1	2	RPS10	0	genetic interference	Srivas R (2016)	1
MTOR	14	TP53	0	affinity chromatography technology, genetic interference	Su WC (2009), Ye H (2016)	2
HECW2	13	SNW1	0	affinity chromatography technology	Lu L (2013)	1
TOP1	1	PRKDC	12	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Ando K (2017), Ando K (2017), Ando K (2017), Ando K (2017), Ando K (2017)	5