Gene Name	Entrez ID	Drug Name	Chembl ID	Interaction Types	Sources	publications

Gene Name	Variant	Alleles	Chemical	Phenotype Category	Significance	Notes	Sentence	Publications	Annotation ID
CYP7A1	rs3808607	GG	atorvastatin	efficacy	not stated	Please note; this variant was described as CYP7A1 A-204C (alleles here are complemented for the plus chromosomal strand). The effect of the rs11887534 C allele was greater in patients with the rs3808607 TT genotype and became smaller with increased number of rs3808607 G alleles.	Genotype GG is associated with decreased response to atorvastatin in people with Hypercholesterolemia as compared to genotype TT.	15262185	982043900
CYP7A1	rs3808607	GG	atorvastatin	efficacy	no	as measured by decreases in LDL-cholestrol. No significant association was seen between all three genotypes and response.	Genotype GG is not associated with response to atorvastatin as compared to genotype TT.	16103896	982045934
CYP7A1	rs3808607	TT	atorvastatin	efficacy	yes	Alleles given as A and C. Response measured as reduction of LDL-C after 8 weeks of treatment with 10mg/day of atorvastatin.	Genotype TT is associated with increased response to atorvastatin in people with Hypercholesterolemia as compared to genotypes GG + GT.	26932749	1447949667