Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
GCKR rs780094 CT + TT fenofibrate efficacy not stated When combined with EITHER rs662799 AG + GG genotypes, OR rs3135506 CG + GG genotypes. This combined genotype group is associated with a greater reduction in triacylglycerol concentrations between baseline and 3 weeks of treatment, as compared to any other genotype combination. Adjusted for baseline triacylglycerol. Genotypes CT + TT are associated with increased response to fenofibrate in people with Hypertriglyceridemia. 19056598 982044657