PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
GSK3B	1	NUB1	2	affinity chromatography technology, affinity chromatography technology	Richet E (2012), Richet E (2012)	2
TP53	0	MUC1	0	affinity chromatography technology, pull down, imaging technique	Wei X (2005), Wei X (2005), Wei X (2005)	3
JUN	0	APP	1	pull down	Miyamoto-Sato E (2010)	1
PRKAR2A	0	GSK3B	1	affinity chromatography technology, affinity chromatography technology	Tanji C (2002), Tanji C (2002)	2
FBXO7	1	GSK3B	1	enzymatic study, affinity chromatography technology, pull down	Teixeira FR (2016), Teixeira FR (2016), Teixeira FR (2016)	3
MYC	2	GSK3B	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference	Gregory MA (2003), Gregory MA (2003), Arnold HK (2009), Zhou Z (2014)	4
PPP1CA	3	PPP1R2	2	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid	Esteves SL (2012), Huttlin EL (2015), St-Denis N (2016), Huttlin EL (2017), Boldt K (2016), Yadav L (2017), Yadav L (2017)	7
NOTCH1	25	NOTCH2	10	affinity chromatography technology	Yatim A (2012)	1
SNAI2	0	TP53	0	affinity chromatography technology	Kao SH (2014)	1
FBXO7	1	AKT3	3	enzymatic study	Teixeira FR (2016)	1
AURKA	1	GSK3B	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kwon YW (2012), Chou CH (2013), Chou CH (2013)	3
ATXN3	2	TP53	0	affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study	Liu H (2016), Liu H (2016), Liu H (2016), Liu H (2016), Liu H (2016)	5
JUN	0	KLF5	4	pull down, pull down	He M (2009), He M (2009)	2
NFATC1	12	PIAS1	4	two hybrid	Nayak A (2009)	1
PRKACA	2	PRKAR2A	0	affinity chromatography technology, biochemical	Varjosalo M (2013), Wan C (2015)	2
GSK3B	1	AKAP11	1	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Tanji C (2002), Tanji C (2002), Tanji C (2002), Tanji C (2002), Varjosalo M (2013)	5
NDRG1	2	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tu LC (2007), Tu LC (2007), Tu LC (2007)	3
BCL3	2	RELB	1	imaging technique	Thornburg NJ (2003)	1
MAP3K1	4	FRAT1	0	affinity chromatography technology, affinity chromatography technology	Loke J (2014), Loke J (2014)	2
HSPA4	3	NDRG1	2	affinity chromatography technology	Ambrosini G (2009)	1
AKT1	1	AR	3	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lin HK (2001), Lin HK (2001), Deep G (2008), Deep G (2008), Steely AM (2017)	5
MAP3K1	4	NOTCH1	25	enzymatic study, affinity chromatography technology	Ahn JS (2016), Ahn JS (2016)	2
APP	1	GSK3B	1	affinity chromatography technology, affinity chromatography technology, pull down	Zhou F (2012), Zhou F (2012), Olah J (2011)	3
IKBKG	0	TBK1	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bouwmeester T (2004), Fenner BJ (2010), Li S (2011), Wang L (2012), Wang L (2012), Ran Y (2016), Huttlin EL (2017)	7
TBK1	1	APP	1	pull down	Olah J (2011)	1
APP	1	MAPT	1	pull down, unspecified method	Guo JP (2006), Guo JP (2006)	2
CCNE1	1	AR	3	affinity chromatography technology	Yamamoto A (2000)	1
TAZ	1	LRP6	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PPP1CA	3	AKT1	1	enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li L (2003), Xiao L (2010), Xiao L (2010), Xiao L (2010), Chen CS (2005), Chen CS (2005)	6
UBR5	13	TP53	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Ling S (2011), Ling S (2011), Ling S (2011), Fogeron ML (2013), Flack JE (2017)	5
JUN	0	CEBPB	2	affinity chromatography technology	Li X (2015)	1
KLF5	4	GSK3B	1	affinity chromatography technology, enzymatic study, enzymatic study	Liu N (2010), Zhao D (2010), Liu N (2010)	3
APC	5	CTNNB1	30	affinity chromatography technology, far western blotting, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, unspecified method, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Su LK (1993), Su LK (1993), Kucerova D (2001), Tickenbrock L (2003), Davies G (2001), Ryo A (2001), Homma MK (2002), Tickenbrock L (2003), Davies G (2001), Satoh K (1997), Eklof Spink K (2001), Eklof Spink K (2001), Sierra J (2006), Choi J (2004), Huang X (2009), Brocardo MG (2011), Xing Y (2004), Xing Y (2004), Xing Y (2004), Hamada F (2004), Hamada F (2004), Schneikert J (2013), Hsi LC (1999), Hein MY (2015), Hein MY (2015), Chen TC (2014), Kuslansky Y (2016), Novellasdemunt L (2017), Novellasdemunt L (2017)	29
DNM1L	3	HSPA4	3	affinity chromatography technology	Malty RH (2017)	1
BCL3	2	JUN	0	two hybrid, pull down, affinity chromatography technology	Na SY (1999), Na SY (1999), Na SY (1999)	3
GSK3B	1	MCL1	1	affinity chromatography technology, enzymatic study	Ding Q (2007), Ding Q (2007)	2
GSK3B	1	NFE2L1	4	affinity chromatography technology, enzymatic study	Biswas M (2013), Biswas M (2013)	2
AR	3	SMAD3	1	affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down	Chipuk JE (2002), Hayes SA (2001), Hayes SA (2001), Hayes SA (2001), Chipuk JE (2002), Hayes SA (2001), Hayes SA (2001), Kang HY (2002), Kang HY (2002), Kang HY (2002), Kang HY (2002), Chipuk JE (2002)	12
SMAD3	1	BTRC	1	affinity chromatography technology	Wan M (2004)	1
DDIT4	0	BTRC	1	affinity chromatography technology	Katiyar S (2009)	1
MAPK1	1	AR	3	pull down	Yeh S (1999)	1
AKT1	1	PIAS1	4	two hybrid	Depaux A (2007)	1
JUN	0	MYC	2	affinity chromatography technology	Levy S (2010)	1
GSK3B	1	JUN	0	enzymatic study, imaging technique	Chen BK (2007), Chen TC (2014)	2
NUB1	2	SNCAIP	2	two hybrid, affinity chromatography technology, two hybrid	Tanji K (2006), Tanji K (2006), Tanji K (2007)	3
PIAS1	4	JUN	0	pull down, enzymatic study	Schmidt D (2002), Schmidt D (2002)	2
MYC	2	MCL1	1	genetic interference	Toyoshima M (2012)	1
CSF3R	2	GSK3B	1	affinity chromatography technology, affinity chromatography technology	Lochab S (2013), Lochab S (2013)	2
AURKA	1	BTRC	1	affinity chromatography technology	Irelan JT (2007)	1
TRAK2	2	GSK3B	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
AURKA	1	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GSK3B	1	AXIN1	1	two hybrid, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology	Nakamura T (1998), Nakamura T (1998), Nakamura T (1998), Nakamura T (1998), Nakamura T (1998), Nakamura T (1998), Mak BC (2003), Hino S (2005), Oosterveen T (2007), Kim MJ (2008), Kitagawa M (1999), Cha B (2011), Cha B (2011), Arnold HK (2009), Kashikar ND (2011), Kashikar ND (2011), Zhou F (2012), Yan D (2012), Zhang YG (2012), Sue Ng S (2010), Kim JW (2003), Tang Y (2008), Luo W (2007), Li VS (2012), Rosano L (2009), Yamamoto H (2006), Fei C (2013), Wang J (2011), Varjosalo M (2013), Gao C (2014), Varjosalo M (2013), Castellone MD (2005), Hein MY (2015), Chen TC (2014), Chen Y (2016), Novellasdemunt L (2017)	36
JUN	0	MAPK1	1	affinity chromatography technology, enzymatic study, pull down	Kumar NV (2001), Zuniga A (1999), Zuniga A (1999)	3
DNM1L	3	GSK3B	1	two hybrid, pull down	Hong YR (1998), Hong YR (1998)	2
MAPK1	1	CEBPB	2	enzymatic study	Hanlon M (2001)	1
BTRC	1	NFE2L1	4	affinity chromatography technology, bioid	Coyaud E (2015), Coyaud E (2015)	2
EYA1	4	GSK3B	1	affinity chromatography technology, enzymatic study	Sun Y (2014), Sun Y (2014)	2
GSK3B	1	GSK3B	1	enzymatic study, enzymatic study, affinity chromatography technology	Fischer L (2002), Kawakami F (2011), Varjosalo M (2013)	3
PPP3CC	0	GSK3B	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
PRKACA	2	MAPT	1	enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Wang JZ (1998), Schneider A (1999), Zheng-Fischhoefer Q (1998), Qureshi HY (2011), Liu F (2002), Sadik G (2009)	6
AURKA	1	APP	1	pull down, pull down	Olah J (2011), Virok DP (2011)	2
PPP3CC	0	NFATC1	12	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
MAPK1	1	BCL3	2	enzymatic study	Wang VY (2017)	1
EYA1	4	MYC	2	enzymatic study, affinity chromatography technology, affinity chromatography technology	Li J (2017), Li J (2017), Li J (2017)	3
AKT1	1	GSK3B	1	pull down, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Thimmaiah KN (2005), Drendall CI (2010), Connor MK (2005), Hunter MG (2004), Zhu QS (2011), Li L (2003), Nam SY (2010), Yang WL (2009), Zeng L (2013), Yang H (2005), Boehme KA (2008), Cross DA (1995), Hinton CV (2007), Kapoor GS (2004), Pitre A (2012), Guo J (2016)	16
AURKA	1	CTNNB1	30	affinity chromatography technology	Hein MY (2015)	1
MAPK1	1	TSC2	17	pull down, affinity chromatography technology	Ma L (2005), Ma L (2005)	2
NFATC2	1	GSK3B	1	affinity chromatography technology, affinity chromatography technology	Gabriel CH (2016), Gabriel CH (2016)	2
PPP3CC	0	APP	1	pull down	Olah J (2011)	1
GSK3B	1	MDM2	2	enzymatic study, affinity chromatography technology	Kulikov R (2005), Kulikov R (2005)	2
MCL1	1	HSPA4	3	affinity chromatography technology, affinity chromatography technology	Bewley MA (2011), Stankiewicz AR (2009)	2
RELB	1	GSK3B	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Neumann M (2011), Neumann M (2011), Neumann M (2011)	3
IKBKG	0	AKT1	1	pull down, affinity chromatography technology	Fenner BJ (2010), Hou Y (2010)	2
SNAI1	1	MDM2	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lim SO (2011), Lim SO (2010), Lim SO (2010)	3
AKT1	1	SNAI1	1	pull down, affinity chromatography technology, pull down, affinity chromatography technology	Villagrasa P (2012), Villagrasa P (2012), Villagrasa P (2012), Villagrasa P (2012)	4
MAPK1	1	SMAD1	0	enzymatic study, enzymatic study, enzymatic study	Sapkota G (2007), Alarcon C (2009), Fuentealba LC (2007)	3
CTNND1	4	GSK3B	1	affinity chromatography technology, affinity chromatography technology	Shrestha H (2017), Shrestha H (2017)	2
AURKA	1	MDM2	2	affinity chromatography technology, enzymatic study	Sehdev V (2013), Sehdev V (2013)	2
MYC	2	PPP1CA	3	affinity chromatography technology	Koch HB (2007)	1
MAP3K1	4	JUN	0	enzymatic study	Park KJ (2003)	1
CTNNB1	30	CTNND1	4	affinity chromatography technology, affinity chromatography technology	Hazan RB (1998), Kucerova D (2001)	2
GSK3B	1	APC	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Davies G (2001), Varjosalo M (2013), Novellasdemunt L (2017)	3
BTRC	1	MDM2	2	affinity chromatography technology, affinity chromatography technology, pull down	Inuzuka H (2010), Inuzuka H (2010), Inuzuka H (2010)	3
TBK1	1	TRAF2	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Bouwmeester T (2004), Bonnard M (2000), Behrends C (2010), Li S (2011), Li S (2011), Shen RR (2012), Zhang W (2010), Huttlin EL (2017), Fang R (2017), Fang R (2017)	10
SMAD3	1	JUN	0	two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology	Zhang Y (1998), Zhang Y (1998), Zhang Y (1998), Verrecchia F (2000), Liberati NT (1999), Liberati NT (2001), Lee SY (2011)	7
STRAP	2	AXIN1	1	affinity chromatography technology	Kashikar ND (2011)	1
PRKACA	2	AKAP11	1	affinity chromatography technology	Varjosalo M (2013)	1
TBK1	1	GSK3B	1	affinity chromatography technology, affinity chromatography technology	Qin Y (2016), Qin Y (2016)	2
NOTCH3	9	MYC	2	pull down	Jung JG (2014)	1
NOTCH1	25	NOTCH3	9	genetic interference, affinity chromatography technology	Beatus P (2001), Yatim A (2012)	2
CD274	2	GSK3B	1	pull down, affinity chromatography technology	Li CW (2016), Li CW (2016)	2
GSK3B	1	CCNE1	1	enzymatic study, imaging technique	Welcker M (2003), Chen TC (2014)	2
MDM2	2	TP53	0	enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, biochemical, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, pull down, protein complementation assay, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, two hybrid, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, pull down, pull down, unspecified method, affinity chromatography technology, two hybrid, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, protein complementation assay, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, x-ray crystallography, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, x-ray crystallography, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, far western blotting, affinity chromatography technology, x-ray crystallography, unspecified method, pull down, pull down, pull down, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference, fluorescent resonance energy transfe, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, biochemical, unspecified method, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, pull down, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down, x-ray crystallography, protein complementation assay, imaging technique, affinity chromatography technology, enzymatic study, affinity chromatography technology, fluorescent resonance energy transfe, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, fluorescent resonance energy transfe, pull down, affinity chromatography technology, pull down, enzymatic study, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, pull down, unspecified method, affinity chromatography technology, imaging technique, enzymatic study, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, enzymatic study, pull down, pull down, unspecified method, fluorescent resonance energy transfe, two hybrid, pull down	Li M (2003), Latonen L (2001), Zhang Y (2003), Zhang Y (2003), Kurki S (2003), Kurki S (2003), Freeman DJ (2003), Ito A (2002), Ito A (2002), Grossman SR (1998), Fang S (2000), Liu G (2000), Zhang Y (1998), Zhang Y (1998), Chen J (1993), Thut CJ (1997), Leung KM (2002), Wawrzynow B (2009), Ochocka AM (2009), Chen D (2009), Hedstroem E (2009), Brenkman AB (2008), Qiu W (2008), Qiu W (2008), Zhang Z (2008), Muller P (2008), Colaluca IN (2008), Colaluca IN (2008), Colaluca IN (2008), Tang Y (2008), Tang Y (2008), Lu X (2007), Lukashchuk N (2007), Lukashchuk N (2007), Lee JH (2007), Carter S (2007), Sasaki M (2007), Brooks CL (2007), Li L (2007), Becker K (2007), Zhao BX (2006), Zhao BX (2006), Abida WM (2007), Yang WH (2006), Ma J (2006), Wallace M (2006), Shimizu H (2006), Andrews P (2006), Yang J (2009), Zhu Z (2009), Wang C (2005), Higashitsuji H (2005), Higashitsuji H (2005), Yan C (2005), Vega FM (2004), Dai MS (2004), Dai MS (2004), Groenroos E (2004), Ohkubo S (2006), Sui G (2004), Di Stefano V (2004), Brignone C (2004), Katayama H (2004), Linares LK (2003), OKeefe K (2003), Wang W (2003), Blattner C (2002), Matt T (2004), Matt T (2004), Eyckerman S (2005), Shimizu H (2002), Shimizu H (2002), Migliorini D (2002), Gu J (2001), Sengupta S (2001), Chernov MV (2001), Cross B (2011), Cross B (2011), Cross B (2011), Buschmann T (2001), Nakamura S (2000), Rodriguez MS (2000), Rodriguez MS (2000), Geyer RK (2000), Zaika A (1999), Maki CG (1999), Chen L (2010), Chen L (2010), Lin RK (2010), Fuchs SY (1998), Xirodimas DP (2001), Fuchs SY (1998), Inoue T (2001), Wu L (2011), Du W (2009), Li DQ (2009), Illuzzi JL (2011), Oliver TG (2011), Kim MM (2007), Marchenko ND (2007), Vaseva AV (2009), Vaseva AV (2009), Lai KP (2010), Naderi EH (2011), Zdzalik M (2010), Singh RK (2007), Meng L (2011), Moore L (2007), Kim S (2010), Inoue Y (2011), Fraser JA (2010), Worrall EG (2009), Wu H (2011), Wang KS (2011), Wang KS (2011), Wang KS (2011), Izumi T (2010), Huang YF (2009), Tang J (2006), Tang J (2006), Fu X (2010), Fu X (2010), Shloush J (2011), Yadavilli S (2009), Stevenson LF (2007), Suzuki T (2010), Cheng Q (2009), Kulikov R (2010), Kulikov R (2010), Li L (2010), Li L (2010), Cheng Q (2011), Li D (2011), Nie J (2010), Demma M (2010), Sun XX (2011), Jung CR (2010), Jung CR (2010), Jung CR (2010), Jung CR (2010), Nishida T (2011), Li M (2011), Li M (2011), Amson R (2011), Amson R (2011), Bhatt P (2011), David Y (2011), Zhang Y (2010), Liu J (2010), Liu J (2010), Song MS (2008), Cummins JM (2004), Kim CK (2010), Kim CK (2010), Yan C (2010), Wang X (2011), Phillips A (2010), Phillips A (2010), Kang HN (2011), Kang HN (2011), Wang X (2004), Sionov RV (2001), Wei S (2012), Camus S (2012), Ding B (2012), Yang Z (2012), Yang Z (2012), Tripathi V (2007), Tripathi V (2007), Dai C (2011), Chen S (2012), Honda R (1997), Kinyamu HK (2003), Zhan C (2012), Zhan C (2012), Lee CW (2010), Zhou X (2012), Bouska A (2008), Wade M (2012), Ferreon JC (2009), Domenici F (2011), Uldrijan S (2007), Uldrijan S (2007), Stad R (2000), Stad R (2000), Banks D (2006), Banks D (2006), Bernal F (2010), Bernal F (2010), Jain AK (2012), Kane SA (2000), Tan Z (2000), Yang Z (2012), Wawrzynow B (2007), Wawrzynow B (2007), Wawrzynow B (2007), Hiramatsu K (2006), Bao-Lei T (2006), Kulikov R (2005), Yang Y (2005), Lindstroem MS (2007), Bech-Otschir D (2001), Li Y (2012), Gillotin S (2010), Burch L (2004), Liu WL (2001), OHagan HM (2004), OHagan HM (2004), Funari G (2009), Candeias MM (2008), Brew CT (2006), Wang J (2011), Calabro V (2002), Burch L (2004), Iyappan S (2010), Poyurovsky MV (2010), Poyurovsky MV (2010), Poyurovsky MV (2010), Kurki S (2004), Tian LF (2006), Wang J (2006), Bae S (2012), Bae S (2012), Frazier DP (2012), Frazier DP (2012), Lew QJ (2012), Lew QJ (2012), Huart AS (2012), Li Z (2004), Balint E (1999), Balint E (1999), Funston G (2012), Dou X (2012), Sadagopan S (2012), Sadagopan S (2012), Dixit D (2012), Roxburgh P (2012), Xu L (2012), Drago-Ferrante R (2008), Li H (2009), Negorev D (2001), Wang X (2012), Wang X (2012), Wang X (2012), Boettger A (1997), Jung H (2008), Oliner JD (1992), Seemann S (2005), Kawai H (2007), Schuster K (2007), Dawson R (2003), DArcy P (2009), Schon O (2004), Schon O (2004), Hogan C (2008), Lottin-Divoux S (2005), Latini P (2011), Latini P (2011), Latini P (2011), McCoy MA (2003), Kussie PH (1996), Shieh SY (1997), Shieh SY (1997), Naski N (2009), Naski N (2009), Schon O (2002), Tamborini E (2001), Wade M (2006), Wade M (2006), Lohrum MA (2003), Garcia JF (2002), Garcia JF (2002), Kallen J (2009), Kulikov R (2006), Kulikov R (2006), Czarna A (2009), Czarna A (2009), Hu B (2007), Chi SW (2005), Yu GW (2006), Yu GW (2006), Saji S (2001), Chen L (1997), Zhang H (1998), Issaeva N (2004), Wade M (2008), Wade M (2008), Chen HF (2007), Chen HF (2007), Li HH (2004), Wang J (2011), Gu L (2009), Gu L (2009), Meng L (2008), Meng L (2008), Okamoto K (2006), Malaguarnera R (2008), Zhou M (2003), Zhou M (2003), Di Conza G (2012), Xirodimas DP (2004), Auger KR (2005), Li J (2011), Li J (2011), Li J (2011), Lee SJ (2007), Chau JF (2012), Lu X (2005), Mazars A (2010), Mazars A (2010), Mazars A (2010), Olson DC (1993), Picksley SM (1994), Issaeva N (2004), Issaeva N (2004), Zhang J (2012), Wen W (2013), Wen W (2013), Bursac S (2012), Yang Y (2013), Yang Y (2013), Landre V (2013), Pettersson S (2012), Thin TH (2007), Thin TH (2007), Piccinin S (2012), Shan B (2012), Caratozzolo MF (2012), Lui K (2013), Kobet E (2000), Lim KH (2010), Ranaweera RS (2013), Cui D (2013), Ebina M (2013), He Y (2013), He Y (2013), Siepe D (2009), Suh HW (2013), Zhan YA (2013), Wang J (2011), Hjerpe R (2010), Murray MF (2007), Jin L (2013), Jin L (2013), Zhang R (2013), Yan S (2013), Sun XX (2011), Heyne K (2014), Heyne K (2014), Bista M (2013), Jin J (2014), Mikawa T (2014), Qi M (2014), Cheng Q (2014), Zhang HH (2014), Perry ME (2000), Nishizaki M (2004), Sanchez-Aguilera A (2006), Chen YC (2013), Bertamino A (2013), Ding G (2013), Kubo N (2013), Kubo N (2013), Hsueh KW (2013), Kofod-Olsen E (2014), Fogeron ML (2013), Chang YS (2013), Gotoh T (2014), Gotoh T (2014), Oi N (2014), Corcoran CA (2009), Corcoran CA (2009), Ayroldi E (2014), Wu G (2014), Rajendra R (2004), Zhang J (2014), Lee MG (2014), Lee MG (2014), Freedman DA (1997), Freedman DA (1997), Saxena A (2006), Shi D (2009), Lohrum MA (2001), Lohrum MA (2001), Grossman SR (2003), Yan S (2013), Xirodimas DP (2004), Yasuhara T (2014), Yasuhara T (2014), Yasuhara T (2014), Yasuhara T (2014), Saville MK (2004), Rodriguez MS (1999), Lui K (2013), Wu PY (2003), Pavithra L (2009), He Y (2013), Tan BX (2014), Huttlin EL (2015), Marcar L (2015), Borcherds W (2014), Borcherds W (2014), Li YC (2014), Ayroldi E (2014), Ling X (2014), Batuello CN (2015), Zhu N (2006), Mo XL (2015), Chen TC (2014), Stindt MH (2015), Caratozzolo MF (2014), Li X (2015), Saxena R (2016), Reed SM (2014), Du C (2016), Du C (2016), Du C (2016), Fraser JA (2015), Fraser JA (2015), Wu B (2015), Qin JJ (2015), Raza S (2015), Raza S (2015), Yamauchi T (2014), Yamauchi T (2014), Yamauchi T (2014), Shi Y (2010), Ahn HJ (2015), Lim KH (2015), Kang JH (2016), Chen J (2015), Liu X (2016), Yang P (2016), Yang P (2016), Liu D (2016), Liu D (2016), Liu D (2016), Datta D (2015), Reddy BA (2014), He X (2016), Shostak K (2014), Liu LJ (2016), Liu LJ (2016), Stegh AH (2010), Liu XH (2005), Medina-Medina I (2016), Medina-Medina I (2016), Kayama K (2017), Singh AK (2016), Liu WT (2016), Yue X (2016), Soares J (2015), Mukhopadhyay R (2016), Mukhopadhyay R (2016), Zhou X (2016), Zhou X (2016), Xie X (2016), Leao M (2015), Luo H (2016), Luo H (2016), Xie N (2016), Maeda R (2017), Maeda R (2017), Maeda R (2017), Sheng W (2017), Sheng W (2017), Liu M (2010), Huttlin EL (2017), Chauhan KM (2016), Goetz C (1999), Zhang J (2017), Unger T (1999), Liu Z (2004), Wu W (2015), Tan G (2017), Nomura K (2017), Lu W (2017), Lu W (2017), Hjerrild M (2001), Landre V (2017), Landre V (2017), Landre V (2017), Landre V (2017), Shangary S (2008), Shangary S (2008), Du WW (2017), Du WW (2017), Bista M (2013), Bista M (2013), Jin M (2017), LaRusch GA (2007), LaRusch GA (2007), Kurokawa M (2013), Ivanov AA (2017), Wong JH (2017), Wong JH (2017)	496
TP53	0	SMAD3	1	affinity chromatography technology, pull down, affinity chromatography technology, imaging technique	Cordenonsi M (2003), Cordenonsi M (2003), Lu D (2013), Ali A (2013)	4
AXIN2	1	APC	5	affinity chromatography technology	von Kries JP (2000)	1
BTRC	1	CCNE1	1	enzymatic study, enzymatic study	Saha A (2008), Pierce NW (2013)	2
PPP1CA	3	HSPA4	3	affinity chromatography technology	Flores-Delgado G (2007)	1
MYC	2	AURKA	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
CEBPB	2	KLF5	4	two hybrid, affinity chromatography technology, affinity chromatography technology	Oishi Y (2005), Oishi Y (2005), Oishi Y (2005)	3
CTNNB1	30	GSK3B	1	affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, enzymatic study, enzymatic study, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Davies G (2001), Kishida S (1999), Fischer L (2002), Kitagawa M (1999), Hart M (1999), Su Y (2008), Huang X (2009), Ding Q (2005), Piao S (2008), Varjosalo M (2013), Gao C (2014), Koo J (2015), Chen TC (2014), Lu D (2012), Kuslansky Y (2016), Novellasdemunt L (2017), Lu WJ (2015)	17
PPP1CA	3	AXIN1	1	affinity chromatography technology	Luo W (2007)	1
GSK3B	1	RICTOR	4	enzymatic study, affinity chromatography technology, enzymatic study	Chen CH (2011), Koo J (2015), Koo J (2015)	3
KLF5	4	TP53	0	affinity chromatography technology, affinity chromatography technology	Zhu N (2006), Zhu N (2006)	2
PPP1CA	3	GSK3B	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tanji C (2002), Varjosalo M (2013), St-Denis N (2016)	3
GSK3B	1	SOX10	2	pull down, enzymatic study	Lv XB (2015), Lv XB (2015)	2
FBXO7	1	UBR5	13	affinity chromatography technology	Teixeira FR (2016)	1
MAPK1	1	MAP3K1	4	affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study	Karandikar M (2000), Karandikar M (2000), Gallagher ED (2004), Tu Z (2003), Loke J (2014)	5
AKT1	1	CTNNB1	30	enzymatic study, enzymatic study	Tian Q (2004), Fang D (2007)	2
TSC2	17	AKT1	1	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Dan HC (2002), Roux PP (2004), Dan HC (2002), Dan HC (2002)	4
SNAI2	0	APP	1	pull down	Olah J (2011)	1
NFE2L3	6	GSK3B	1	affinity chromatography technology, enzymatic study	Kannan MB (2015), Kannan MB (2015)	2
AKAP11	1	PPP1CA	3	affinity chromatography technology, affinity chromatography technology, pull down	Tanji C (2002), Tanji C (2002), Schillace RV (1999)	3
NFE2L3	6	NFE2L1	4	fluorescent resonance energy transfe	Reinke AW (2013)	1
SNAI1	1	GSK3B	1	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yook JI (2005), Zhou BP (2004), Zhou BP (2004), Wu Y (2009), Wu Y (2009), Lee JH (2017)	6
GSK3B	1	AR	3	pull down, affinity chromatography technology	Wang L (2004), Wang L (2004)	2
AXIN1	1	TSC2	17	affinity chromatography technology, affinity chromatography technology	Mak BC (2003), Mak BC (2003)	2
BTRC	1	APC	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Kitagawa M (1999), Hart M (1999), Coyaud E (2015), Coyaud E (2015), Huttlin EL (2017), Novellasdemunt L (2017)	7
NFATC1	12	GSK3B	1	affinity chromatography technology, affinity chromatography technology	Gabriel CH (2016), Gabriel CH (2016)	2
TRAF2	1	FBXO7	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kuiken HJ (2012), Chen CM (2014), Huttlin EL (2017)	3
MAP3K1	4	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Islam MR (2010), Islam MR (2010), Chipps E (2015), Chipps E (2015), Chipps E (2015)	5
GSK3B	1	DEAF1	12	enzymatic study, affinity chromatography technology	Pilot-Storck F (2010), Pilot-Storck F (2010)	2
NFATC1	12	NFATC2	1	affinity chromatography technology	Gabriel CH (2016)	1
NFATC1	12	TP53	0	affinity chromatography technology	Li X (2015)	1
SMAD3	1	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tian YC (2002), Dahle O (2010), Charbonney E (2011), Zhou B (2012)	4
TAZ	1	GSK3B	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Huang W (2012), Huang W (2012), Huang W (2012)	3
APP	1	MYC	2	pull down	Virok DP (2011)	1
GSK3B	1	SMAD1	0	enzymatic study, imaging technique	Fuentealba LC (2007), Chen TC (2014)	2
APC	5	UBR5	13	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ohshima R (2007), Ohshima R (2007), Ohshima R (2007)	3
SMAD3	1	CEBPB	2	pull down	Choy L (2003)	1
TRAF2	1	MAP3K1	4	biochemical, affinity chromatography technology, affinity chromatography technology, enzymatic study, imaging technique	Baud V (1999), Baud V (1999), Wu Y (2006), Charlaftis N (2014), Chen TC (2014)	5
GSK3B	1	MAPT	1	enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Shimura H (2004), Wang JZ (1998), Richet E (2012), Richet E (2012), Schneider A (1999), Kawakami F (2011), Kawakami F (2011), Zheng-Fischhoefer Q (1998), Virdee K (2007), Liu F (2002), Sadik G (2009), Sasaki K (2009), Liu F (2006), Watcharasit P (2002)	14
STRAP	2	SMAD3	1	affinity chromatography technology, affinity chromatography technology, genetic interference, genetic interference	Datta PK (2000), Datta PK (2000), Datta PK (2000), Datta PK (2000)	4
TP53	0	HSPA4	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Muller P (2008), Fraser JA (2010), Sun Y (2007), Wang J (2011), Horikawa I (2014), Horikawa I (2014), Kishor A (2013)	7
PPP1CA	3	AURKA	1	pull down, affinity chromatography technology, pull down, enzymatic study, enzymatic study	Katayama H (2001), Katayama H (2001), Katayama H (2001), Katayama H (2001), Katayama H (2001)	5
GSK3B	1	MAP3K1	4	affinity chromatography technology, pull down	Kim JW (2003), Kim JW (2003)	2
AR	3	PIAS1	4	two hybrid, affinity chromatography technology	Kotaja N (2000), Toropainen S (2015)	2
KLF5	4	SMAD3	1	affinity chromatography technology	Guo P (2009)	1
SMAD3	1	SMAD1	0	affinity chromatography technology, two hybrid, two hybrid	Brown KA (2008), Wu RY (1997), Wu RY (1997)	3
MDM2	2	JUN	0	pull down	Miyamoto-Sato E (2010)	1
IKBKG	0	MUC1	0	affinity chromatography technology	Ahmad R (2007)	1
AXIN1	1	AXIN2	1	affinity chromatography technology	Sue Ng S (2010)	1
GSK3B	1	FRAT1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Varjosalo M (2013), Hein MY (2015)	3
CTNNB1	30	CCNE1	1	pull down, affinity chromatography technology, affinity chromatography technology	Park CS (2004), Park CS (2004), Park CS (2004)	3
MYC	2	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP3K1	4	AXIN1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zhang Y (2002), Zhang Y (2000), Zhang Y (2000), Sue Ng S (2010), Sue Ng S (2010), Loke J (2014)	6
MAPK1	1	TP53	0	affinity chromatography technology, affinity chromatography technology, protein complementation assay, affinity chromatography technology, imaging technique	Persons DL (2000), How PC (2011), Srivastav RK (2011), Fogeron ML (2013), Chen TC (2014)	5
SMAD3	1	APP	1	pull down	Olah J (2011)	1
TP53	0	SNAI1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lim SO (2010), Lim SO (2010), Liu T (2017)	3
MYC	2	MAPK1	1	pull down, pull down	Jin Z (2004), Gupta S (1994)	2
NOTCH1	25	MAPK1	1	affinity chromatography technology, affinity chromatography technology	Yatim A (2012), Yatim A (2012)	2
GSK3B	1	STRAP	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Kashikar ND (2011), Kashikar ND (2011)	3
NFATC2	1	JUN	0	pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nguyen TN (2010), Nguyen TN (2010), Li X (2015), Gabriel CH (2016), Gabriel CH (2016)	5
NOTCH3	9	STRAP	2	affinity chromatography technology, affinity chromatography technology	Kashikar ND (2011), Kashikar ND (2011)	2
JUN	0	NFE2L1	4	affinity chromatography technology, pull down	Venugopal R (1998), Venugopal R (1998)	2
MDM2	2	SNAI2	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jung CH (2013), Lin TY (2016), Lin TY (2016)	3
AR	3	PPP1CA	3	affinity chromatography technology, affinity chromatography technology	Liu X (2016), Liu X (2016)	2
AXIN1	1	APC	5	pull down, two hybrid, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nakamura T (1998), Nakamura T (1998), Nakamura T (1998), Nakamura T (1998), Hino S (2005), Kitagawa M (1999), Sue Ng S (2010), Tran H (2012), Li VS (2012), Hein MY (2015), Hein MY (2015), Novellasdemunt L (2017)	12
NDRG1	2	MYC	2	affinity chromatography technology, affinity chromatography technology	Wang Y (2017), Wang Y (2017)	2
LRP6	3	GSK3B	1	affinity chromatography technology, enzymatic study, far western blotting	Yamamoto H (2006), Piao S (2008), Piao S (2008)	3
PPP1CA	3	MDM2	2	affinity chromatography technology	Liu X (2016)	1
PPP1CA	3	DEAF1	12	two hybrid	Esteves SL (2012)	1
MCL1	1	TP53	0	unspecified method, affinity chromatography technology	Lee MS (2014), Zhang X (2016)	2
CEBPB	2	AR	3	pull down	Boruk M (1998)	1
NOTCH3	9	GSK3B	1	affinity chromatography technology, affinity chromatography technology	Kashikar ND (2011), Kashikar ND (2011)	2
SMAD1	0	NOTCH2	10	two hybrid	Colland F (2004)	1
CTNNB1	30	AR	3	pull down, two hybrid, two hybrid, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Yang F (2002), Yang F (2002), Masiello D (2004), Song LN (2004), Amir AL (2003), Amir AL (2003), Mulholland DJ (2003), Mulholland DJ (2003), Pawlowski JE (2002), Mulholland DJ (2003), Levy L (2004)	11
GSK3B	1	NOTCH1	25	enzymatic study, pull down	Foltz DR (2002), Foltz DR (2002)	2
IKBKG	0	HSPA4	3	affinity chromatography technology	Ammirante M (2010)	1
MDM2	2	HSPA4	3	affinity chromatography technology	Lu TL (2010)	1
SMAD3	1	NOTCH1	25	pull down, affinity chromatography technology	Blokzijl A (2003), Blokzijl A (2003)	2
AURKA	1	CCNE1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
BTRC	1	PRKACA	2	affinity chromatography technology	Sowa ME (2009)	1
GSK3B	1	SNCAIP	2	enzymatic study, affinity chromatography technology	Avraham E (2005), Avraham E (2005)	2
SMAD3	1	HSPA4	3	affinity chromatography technology	Brown KA (2008)	1
PPP1CA	3	SNCAIP	2	two hybrid, two hybrid, imaging technique	Esteves SL (2012), Ferreira-Fernandes E (2015), Ferreira-Fernandes E (2015)	3
HSPA4	3	APP	1	affinity chromatography technology	Kumar P (2007)	1
GSK3B	1	NOTCH2	10	enzymatic study, pull down, affinity chromatography technology	Espinosa L (2003), Espinosa L (2003), Espinosa L (2003)	3
SMAD1	0	PIAS1	4	two hybrid	Colland F (2004)	1
GSK3B	1	PRKACA	2	affinity chromatography technology, enzymatic study, affinity chromatography technology	Fang X (2000), Fang X (2000), Varjosalo M (2013)	3
CTNNB1	30	BTRC	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, x-ray crystallography, enzymatic study, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, protein complementation assay, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology, enzymatic study, protein complementation assay, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yang J (2006), Yang J (2006), Cong F (2003), Kitagawa M (1999), Kitagawa M (1999), Kitagawa M (1999), Hart M (1999), Hart M (1999), Hart M (1999), Su Y (2008), Winston JT (1999), Peschiaroli A (2010), Latres E (1999), Liu J (2004), Dorrello NV (2006), Godin JD (2010), Guardavaccaro D (2008), Evrard-Todeschi N (2008), Saha A (2008), Saha A (2008), Chen CH (2012), Wei S (2008), Dehan E (2009), Wang D (2011), Gao D (2011), Li VS (2012), Sahasrabuddhe AA (2014), Mbom BC (2014), Mbom BC (2014), Kovacev J (2014), Gao C (2014), Kluge SF (2013), Chong RA (2014), Herrero-Ruiz J (2014), Zhang L (2012), Coyaud E (2015), Loveless TB (2015), Low TY (2014), Coyaud E (2015), Tseng RC (2015), Wu K (2016), Villalobos V (2010), Pierce NW (2009), Shrestha H (2016), Gu JJ (2016), Vaid M (2011)	46
PIAS1	4	MDM2	2	enzymatic study	Miyauchi Y (2002)	1
BCL3	2	CTNNB1	30	affinity chromatography technology	Kim JH (2005)	1
GSK3B	1	TP53	0	affinity chromatography technology, two hybrid	Watcharasit P (2002), Vinayagam A (2011)	2
AXIN2	1	GSK3B	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	von Kries JP (2000), Schwarz-Romond T (2002), Varjosalo M (2013), Varjosalo M (2013)	4
BTRC	1	AXIN1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, bioid, affinity chromatography technology	Kitagawa M (1999), Kitagawa M (1999), Li VS (2012), Coyaud E (2015), Coyaud E (2015), Novellasdemunt L (2017)	6
MDM2	2	AKT1	1	affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, imaging technique	Lin HK (2002), Ogawara Y (2002), Zhou BP (2001), Zhou BP (2001), Kim CK (2011), Kim CK (2011), Zhu QS (2011), Milne D (2004), Deep G (2008), Deep G (2008), Chen TC (2014)	11
PPP1CA	3	PIAS1	4	two hybrid	Esteves SL (2012)	1
SMAD3	1	TSC2	17	affinity chromatography technology, affinity chromatography technology, pull down	Birchenall-Roberts MC (2004), Birchenall-Roberts MC (2004), Birchenall-Roberts MC (2004)	3
AKT1	1	BCL3	2	enzymatic study	Wang VY (2017)	1
AXIN1	1	TP53	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference, pull down	Li Q (2011), Li Q (2011), He Y (2013), He Y (2013), He Y (2013), He Y (2013)	6
IKBKG	0	MYC	2	affinity chromatography technology	Kim BY (2010)	1
LRP6	3	CTNNB1	30	affinity chromatography technology	Yamamoto H (2006)	1
TAZ	1	BTRC	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study	Liu CY (2010), Liu CY (2010), Huang W (2012), Cordenonsi M (2011), Liu CY (2010)	5
MUC1	0	CTNNB1	30	pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Yamamoto M (1997), Li Y (2003), Li Y (1998), Li Y (1998), Schroeder JA (2003), Yamamoto M (1997), Li Y (2001), Li Y (2001), Ren J (2002), Li Y (2001), Li Y (2001)	11
FRAT1	0	PIAS1	4	affinity chromatography technology	Hein MY (2015)	1
SMAD1	0	AR	3	affinity chromatography technology, affinity chromatography technology, protein complementation assay, imaging technique, affinity chromatography technology	Qiu T (2007), Qiu T (2007), Qiu T (2007), Qiu T (2007), Li Y (2013)	5
AKT1	1	HSPA4	3	affinity chromatography technology	Doong H (2003)	1
SGK3	0	APP	1	pull down	Olah J (2011)	1
GSK3B	1	DDIT4	0	enzymatic study, affinity chromatography technology	Katiyar S (2009), Katiyar S (2009)	2
PRKAR2A	0	AKAP11	1	unspecified method, affinity chromatography technology, affinity chromatography technology, pull down	Alto NM (2003), Tanji C (2002), Tanji C (2002), Lester LB (1996)	4
MYC	2	MDM2	2	fluorescent resonance energy transfe	Ivanov AA (2017)	1
HSPA4	3	DDIT4	0	two hybrid	Lim J (2006)	1
MAPK1	1	UBR5	13	enzymatic study, affinity chromatography technology	Eblen ST (2003), Eblen ST (2003)	2
MYC	2	CEBPB	2	affinity chromatography technology	Tinel M (2003)	1
MUC1	0	CTNND1	4	affinity chromatography technology, affinity chromatography technology, pull down, imaging technique	Li Y (2001), Li Y (2001), Li Y (2001), Li Y (2001)	4
AXIN1	1	LRP6	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, far western blotting, affinity chromatography technology	Sue Ng S (2010), Li VS (2012), Yamamoto H (2006), Yamamoto H (2006), Piao S (2008), Fei C (2013)	6
JUN	0	NBR1	0	affinity chromatography technology	Li X (2015)	1
AXIN2	1	CTNNB1	30	affinity chromatography technology	von Kries JP (2000)	1
MYC	2	BTRC	1	affinity chromatography technology, enzymatic study	Popov N (2010), Popov N (2010)	2
BTRC	1	TP53	0	affinity chromatography technology, affinity chromatography technology	Xia Y (2009), Verma S (2011)	2
AKT1	1	APP	1	pull down	Olah J (2011)	1
EPM2A	1	GSK3B	1	two hybrid, affinity chromatography technology, affinity chromatography technology	Lohi H (2005), Lohi H (2005), Lohi H (2005)	3
SMAD1	0	APP	1	pull down	Olah J (2011)	1
GSK3B	1	MUC1	0	pull down, affinity chromatography technology, pull down, affinity chromatography technology	Li Y (1998), Li Y (1998), Li Y (2001), Li Y (2001)	4
TSC2	17	GSK3B	1	affinity chromatography technology, enzymatic study, affinity chromatography technology	Mak BC (2003), Inoki K (2006), Mak BC (2003)	3
RICTOR	4	AKT1	1	enzymatic study, enzymatic study, enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study, imaging technique, enzymatic study	Sarbassov DD (2006), Sarbassov DD (2005), Ikenoue T (2008), Murata H (2011), Woods NT (2012), Kim EK (2011), Chen CH (2011), Garcia-Martinez JM (2009), Chen TC (2014), Pitre A (2012)	10
MYC	2	CTNND1	4	affinity chromatography technology	Agrawal P (2010)	1
TBK1	1	BTRC	1	affinity chromatography technology	Bouwmeester T (2004)	1
BTRC	1	MCL1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, enzymatic study	Dehan E (2009), Ding Q (2007), Ding Q (2007), Ding Q (2007), Ding Q (2007)	5
TP53	0	AURKA	1	two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, genetic interference, pull down, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Chen SS (2002), Chen SS (2002), Chen SS (2002), Chen SS (2002), Chen SS (2002), Katayama H (2004), Katayama H (2004), Katayama H (2004), Katayama H (2004), Hsueh KW (2013), Huttlin EL (2015), Huttlin EL (2017)	12
MYC	2	TP53	0	affinity chromatography technology, fluorescent resonance energy transfe	Agrawal P (2010), Ivanov AA (2017)	2
AURKA	1	IKBKG	0	affinity chromatography technology	Irelan JT (2007)	1
AR	3	TP53	0	genetic interference	Shenk JL (2001)	1
CTNNB1	30	APP	1	pull down	Olah J (2011)	1
CTNND1	4	BTRC	1	affinity chromatography technology, affinity chromatography technology	Shrestha H (2016), Shrestha H (2016)	2
GSK3B	1	SNAI2	0	enzymatic study, enzymatic study, affinity chromatography technology, affinity chromatography technology	Wu ZQ (2012), Kao SH (2014), Kao SH (2014), Kao SH (2014)	4
JUN	0	NFATC1	12	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Li X (2015), Li X (2015), Gabriel CH (2016)	3
SMYD2	0	TP53	0	enzymatic study, affinity chromatography technology, affinity chromatography technology	Huang J (2006), Huang J (2006), Abu-Farha M (2008)	3
RICTOR	4	HSPA4	3	affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Pearce LR (2007), Martin J (2008), Martin J (2008), Martin J (2008)	4
GSK3B	1	HSPA4	3	enzymatic study, pull down	Muller P (2012), Kawakami F (2011)	2
TP53	0	SMAD1	0	affinity chromatography technology, affinity chromatography technology	Chau JF (2012), Chau JF (2012)	2
TRAF2	1	GSK3B	1	affinity chromatography technology, affinity chromatography technology	Behrends C (2010), Huttlin EL (2017)	2
IKBKG	0	BTRC	1	affinity chromatography technology	Orel L (2010)	1
MYC	2	SMAD3	1	affinity chromatography technology, pull down, two hybrid	Feng XH (2002), Feng XH (2002), Feng XH (2002)	3
GSK3B	1	NBR1	0	enzymatic study, affinity chromatography technology	Nicot AS (2014), Nicot AS (2014)	2
SMYD2	0	GSK3B	1	affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Ewing RM (2007)	2
AKT1	1	MAPT	1	enzymatic study	Sadik G (2009)	1
AXIN1	1	MYC	2	affinity chromatography technology, affinity chromatography technology, pull down	Arnold HK (2009), Arnold HK (2009), Arnold HK (2009)	3
CEBPB	2	GSK3B	1	affinity chromatography technology, affinity chromatography technology	Lee SH (2010), Lee SH (2010)	2
AKT3	3	AKT1	1	affinity chromatography technology	Huttlin EL (2017)	1
CTNNB1	30	AXIN1	1	pull down, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nakamura T (1998), Nakamura T (1998), Nakamura T (1998), Nakamura T (1998), Nakamura T (1998), Nakamura T (1998), Hocevar BA (2003), Hino S (2005), Stoothoff WH (2002), Kim MJ (2008), Kitagawa M (1999), Kitagawa M (1999), Arnold HK (2009), Zhang YG (2012), Godin JD (2010), Godin JD (2010), Sue Ng S (2010), Sue Ng S (2010), Tang Y (2008), Li VS (2012), Yamamoto H (2006), Fei C (2013), Hein MY (2015), Kuslansky Y (2016), Novellasdemunt L (2017)	25
ATXN3	2	APP	1	pull down	Olah J (2011)	1
NDRG1	2	GSK3B	1	affinity chromatography technology, pull down	Lu WJ (2015), Lu WJ (2015)	2
TP53	0	NUB1	2	affinity chromatography technology, affinity chromatography technology	Liu G (2010), Liu G (2010)	2
TRAF2	1	JUN	0	enzymatic study	Park KJ (2003)	1
MAPT	1	NUB1	2	affinity chromatography technology, affinity chromatography technology	Richet E (2012), Richet E (2012)	2
APC	5	MUC1	0	affinity chromatography technology	Hattrup CL (2004)	1
GSK3B	1	BTRC	1	affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down	Kitagawa M (1999), Gao C (2014), Gao C (2014), Gao C (2014)	4
SMYD2	0	AXIN1	1	affinity chromatography technology	Ewing RM (2007)	1
UBR5	13	CTNNB1	30	affinity chromatography technology	Flack JE (2017)	1
NOTCH1	25	CTNNB1	30	affinity chromatography technology, affinity chromatography technology, pull down	Jin YH (2009), Jin YH (2009), Jin YH (2009)	3
UBR5	13	GSK3B	1	affinity chromatography technology, pull down	Hay-Koren A (2011), Hay-Koren A (2011)	2
TRAF2	1	IKBKG	0	affinity chromatography technology, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Tang ED (2003), Poyet JL (2000), Shen RR (2012), Shen RR (2012), Bal E (2017), Bal E (2017)	6
ATXN3	2	DNM1L	3	affinity chromatography technology	Kristensen LV (2018)	1
PPP1CA	3	TP53	0	two hybrid	Colland F (2004)	1
MAPK1	1	GSK3B	1	affinity chromatography technology, pull down, enzymatic study	Ding Q (2005), Ding Q (2005), Ding Q (2005)	3
TP53	0	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
NOTCH1	25	APP	1	genetic interference, affinity chromatography technology	Kim SY (2007), Kim SY (2007)	2
AR	3	MDM2	2	affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Zoubeidi A (2007), Gaughan L (2005), Gaughan L (2005), Chymkowitch P (2011), Chymkowitch P (2011), Liu T (2012), Liu T (2012), Deep G (2008), Deep G (2008), Lin HK (2002), Lin HK (2002), Zhang A (2015), Kwegyir-Afful AK (2015), McClurg UL (2016), McClurg UL (2016), Liao Y (2017), Steely AM (2017), Zhai W (2016)	18
TP53	0	PIAS1	4	two hybrid, pull down, enzymatic study, pull down, enzymatic study, enzymatic study, imaging technique, pull down	Gallagher WM (1999), Kahyo T (2001), Kahyo T (2001), Schmidt D (2002), Pelisch F (2010), Schmidt D (2002), Chen TC (2014), Okubo S (2004)	8
NFATC2	1	PPP1CA	3	affinity chromatography technology	Gabriel CH (2016)	1
CCNE1	1	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MUC1	0	JUN	0	affinity chromatography technology	Behrens ME (2010)	1
SMYD2	0	AKAP11	1	affinity chromatography technology	Ewing RM (2007)	1
GSK3B	1	ATXN3	2	two hybrid, pull down, affinity chromatography technology, enzymatic study	Vinayagam A (2011), Fei E (2007), Fei E (2007), Fei E (2007)	4
SNAI1	1	BTRC	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yook JI (2005), Zhou BP (2004), Vinas-Castells R (2010), Wu Y (2009)	4
PIAS1	4	GSK3B	1	affinity chromatography technology, enzymatic study	Coon TA (2015), Coon TA (2015)	2
MYC	2	AKT1	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
GSK3B	1	ZFPM1	8	affinity chromatography technology, two hybrid	Wang J (2011), Wang J (2011)	2
GSK3B	1	BCL3	2	enzymatic study, affinity chromatography technology	Viatour P (2004), Viatour P (2004)	2
MDM2	2	APP	1	pull down	Miyamoto-Sato E (2010)	1
GSK3B	1	SMAD3	1	affinity chromatography technology, pull down, affinity chromatography technology	Guo X (2008), Guo X (2008), Choi SI (2011)	3
JUN	0	AR	3	affinity chromatography technology, affinity chromatography technology	Sato N (1997), Sato N (1997)	2
MAPK1	1	SMAD3	1	enzymatic study, affinity chromatography technology	Alarcon C (2009), Brown KA (2008)	2
MAP3K1	4	ATXN3	2	enzymatic study	Charlaftis N (2014)	1
BCL3	2	HSPA4	3	affinity chromatography technology	Keutgens A (2010)	1
AKT1	1	TBK1	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Joung SM (2011), Joung SM (2011), Joung SM (2011)	3
HSPA4	3	NUB1	2	biochemical	Hidalgo-de-Quintana J (2008)	1
GSK3B	1	PPP1R2	2	affinity chromatography technology, affinity chromatography technology	Varjosalo M (2013), Varjosalo M (2013)	2
MAPT	1	HSPA4	3	affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology	Petrucelli L (2004), Kawakami F (2011), Jinwal UK (2012), Jinwal UK (2012), Jinwal UK (2012)	5
MDM2	2	NOTCH1	25	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, enzymatic study	Lim SO (2011), Lim SO (2011), Pettersson S (2012), Pettersson S (2012), Pettersson S (2012)	5
CTNND1	4	APP	1	pull down, pull down	Olah J (2011), Virok DP (2011)	2
KLF5	4	CTNNB1	30	affinity chromatography technology, affinity chromatography technology	McConnell BB (2009), McConnell BB (2009)	2
SNAI1	1	NOTCH1	25	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Lim SO (2011), Lim SO (2011), Lim SO (2011), Lim SO (2011)	4
GSK3B	1	GSKIP	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Ewing RM (2007), Varjosalo M (2013), Varjosalo M (2013)	3
SGK3	0	GSK3B	1	two hybrid, affinity chromatography technology, two hybrid	Dai F (2002), Dai F (2002), Wang J (2011)	3
SMAD3	1	AKT1	1	affinity chromatography technology, imaging technique	Song K (2006), Chen TC (2014)	2
MAPK1	1	MCL1	1	enzymatic study	Ding Q (2007)	1
AURKA	1	CTNND1	4	affinity chromatography technology	Fogeron ML (2013)	1
AKT3	3	GSK3B	1	enzymatic study, enzymatic study	Dragoi AM (2005), Guo J (2016)	2
GSK3B	1	IKBKG	0	imaging technique, enzymatic study, affinity chromatography technology, affinity chromatography technology	Chen TC (2014), Medunjanin S (2016), Medunjanin S (2016), Medunjanin S (2016)	4
AKT1	1	NOTCH1	25	enzymatic study, two hybrid	Song J (2008), Daakour S (2016)	2