PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
YWHAZ	1	APP	1	pull down	Olah J (2011)	1
FARP2	1	PRKCI	1	affinity chromatography technology	Huttlin EL (2017)	1
VHL	0	HNRNPL	3	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lai Y (2011), Yao P (2013), Yao P (2013)	3
NPM1	0	CDC37	0	affinity chromatography technology	Chen R (2013)	1
SMURF1	4	PRKCI	1	enzymatic study	Andrews PS (2010)	1
MAP1LC3B	1	PRKCI	1	affinity chromatography technology	Behrends C (2010)	1
TRIM25	5	ZNF609	4	affinity chromatography technology	Choudhury NR (2017)	1
PRKCI	1	TJP1	2	imaging technique	Suzuki A (2001)	1
GABARAPL2	0	NIPSNAP1	3	affinity chromatography technology	Behrends C (2010)	1
CRX	0	PRKCI	1	affinity chromatography technology	Waaijers S (2013)	1
HSP90AA1	7	IKBKG	0	affinity chromatography technology, affinity chromatography technology	Gano JJ (2010), Hein MY (2015)	2
YWHAE	0	DCAF7	4	affinity chromatography technology, affinity chromatography technology	Gloeckner CJ (2007), Boldt K (2016)	2
HNRNPL	3	APP	1	affinity chromatography technology	Fei T (2017)	1
XPO1	8	NIPSNAP2	1	affinity chromatography technology	Kirli K (2015)	1
TMEM17	0	PARD3	5	bioid	Gupta GD (2015)	1
PRKCZ	5	NPM1	0	affinity chromatography technology, affinity chromatography technology	Chen R (2013), Chen R (2013)	2
CDC37	0	APP	1	two hybrid	Soler-Lopez M (2011)	1
HNRNPL	3	ZNF609	4	affinity chromatography technology	Fei T (2017)	1
YWHAZ	1	HNRNPL	3	affinity chromatography technology	Ewing RM (2007)	1
YWHAH	0	PARD6G	0	affinity chromatography technology	Brajenovic M (2004)	1
PARD6A	0	MAP2K5	1	two hybrid, two hybrid, affinity chromatography technology	Lamark T (2003), Lamark T (2003), Lamark T (2003)	3
DCAF7	4	PRKCI	1	affinity chromatography technology	Boldt K (2016)	1
PRKCI	1	RAB4A	0	affinity chromatography technology	Imamura T (2003)	1
AMOT	6	NIPSNAP1	3	bioid	Couzens AL (2013)	1
XPO1	8	YWHAH	0	biochemical	Kristensen AR (2012)	1
SMURF1	4	XPO1	8	affinity chromatography technology	Tajima Y (2003)	1
TMEM17	0	YWHAH	0	bioid	Gupta GD (2015)	1
CDC37	0	SQSTM1	0	two hybrid, affinity chromatography technology	Vinayagam A (2011), Li J (2013)	2
KERA	0	PRKCI	1	affinity chromatography technology	Huttlin EL (2017)	1
PARD3	5	YWHAH	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brajenovic M (2004), Brajenovic M (2004), Hein MY (2015)	3
NPM1	0	SQSTM1	0	affinity chromatography technology	Chen R (2013)	1
PARD6A	0	MARK4	6	affinity chromatography technology	Brajenovic M (2004)	1
UBC	7	SSB	0	affinity chromatography technology	Matsumoto M (2005)	1
HNRNPL	3	TJP1	2	affinity chromatography technology	Fei T (2017)	1
CASP8	1	PRKCI	1	two hybrid	Wang J (2011)	1
GAPDH	0	NPM1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lee SB (2012), Lee SB (2012), Chen R (2013)	3
HNRNPL	3	RAPGEF2	5	affinity chromatography technology	Fei T (2017)	1
TRIM25	5	HSP90AA1	7	affinity chromatography technology	Choudhury NR (2017)	1
CHUK	5	CASP8	1	affinity chromatography technology	Chaudhary PM (2000)	1
CEP135	2	PRKCI	1	bioid	Gupta GD (2015)	1
RIPK4	0	HSP90AA1	7	affinity chromatography technology	Rodriguez J (2016)	1
SMURF1	4	UBC	7	affinity chromatography technology, enzymatic study, pull down	Xie Y (2013), Kristariyanto YA (2015), Zhang Y (2017)	3
AMOT	6	RASSF8	2	bioid	Couzens AL (2013)	1
PARD6G	0	YWHAE	0	affinity chromatography technology	Brajenovic M (2004)	1
YWHAH	0	RASSF8	2	affinity chromatography technology, affinity chromatography technology	Brajenovic M (2004), Hein MY (2015)	2
UBC	7	IKBKB	1	pull down	Zhang X (2017)	1
ELAVL1	0	PRKCI	1	affinity chromatography technology	Abdelmohsen K (2009)	1
SQSTM1	0	NIPSNAP2	1	affinity chromatography technology, affinity chromatography technology	Behrends C (2010), Milan E (2015)	2
RIPK4	0	FARP2	1	affinity chromatography technology	Rodriguez J (2016)	1
GABARAPL1	0	NIPSNAP2	1	affinity chromatography technology	Behrends C (2010)	1
ELAVL1	0	VHL	0	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Abdelmohsen K (2009), Datta K (2005), Datta K (2005), Yuen JS (2007)	4
HSP90AA1	7	MAGED2	1	biochemical	Kristensen AR (2012)	1
USP21	2	MARK4	6	affinity chromatography technology	Sowa ME (2009)	1
TRIM25	5	APP	1	affinity chromatography technology	Choudhury NR (2017)	1
PARD3	5	PRKCI	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kohjima M (2002), Kohjima M (2002), Brajenovic M (2004), Brajenovic M (2004), Yang Z (2012)	5
TRIM25	5	MARK4	6	affinity chromatography technology	Choudhury NR (2017)	1
VHL	0	CD44	1	pull down	Lai Y (2012)	1
AMOT	6	APP	1	pull down	Olah J (2011)	1
RIPK4	0	CDC37	0	affinity chromatography technology	Rodriguez J (2016)	1
RHOJ	0	PARD6G	0	affinity chromatography technology	Huttlin EL (2017)	1
GPR156	2	FARP2	1	affinity chromatography technology	Huttlin EL (2017)	1
PRKCI	1	SQSTM1	0	two hybrid, pull down, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, unspecified method, affinity chromatography technology, fluorescent resonance energy transfe	Sanchez P (1998), Sanchez P (1998), Sanchez P (1998), Sanchez P (1998), Behrends C (2010), Brajenovic M (2004), Lamark T (2003), Lamark T (2003), Lamark T (2003), Yang JQ (2010), Yang JQ (2010), Erdogan E (2006), Milan E (2015), Tsai LC (2015), Tsai LC (2015), Tsai LC (2015)	16
HNRNPL	3	MBP	0	affinity chromatography technology	Fei T (2017)	1
HNRNPL	3	BAD	1	affinity chromatography technology	Fei T (2017)	1
HSP90AA1	7	APP	1	affinity chromatography technology	Kumar P (2007)	1
GABARAPL2	0	NIPSNAP2	1	affinity chromatography technology	Behrends C (2010)	1
HNRNPL	3	PRKCI	1	affinity chromatography technology	Fei T (2017)	1
VHL	0	APP	1	pull down	Olah J (2011)	1
TRIM25	5	ELAVL1	0	affinity chromatography technology, affinity chromatography technology	Choudhury NR (2017), Choudhury NR (2017)	2
YWHAZ	1	PRKCZ	5	pull down, enzymatic study	Zemlickova E (2003), Van Der Hoeven PC (2000)	2
VHL	0	PRKCI	1	enzymatic study	Okuda H (2001)	1
PRKCI	1	4651	0	affinity chromatography technology	Brajenovic M (2004)	1
XPO1	8	NPM1	0	unspecified method	Xu D (2012)	1
KBTBD7	3	PRKCI	1	affinity chromatography technology	Huttlin EL (2017)	1
UBC	7	PRKCI	1	pull down	Zhang X (2017)	1
PRKCI	1	FRS2	0	two hybrid, pull down	Lim YP (1999), Lim YP (1999)	2
HSP90AA1	7	CDK7	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Taipale M (2012), Huttlin EL (2015), Huttlin EL (2017)	3
PRKCI	1	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology	Brajenovic M (2004), Taipale M (2012)	2
PARD6B	0	4651	0	affinity chromatography technology	Hein MY (2015)	1
SQSTM1	0	UBC	7	two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, unspecified method, x-ray crystallography, affinity chromatography technology, unspecified method, pull down, pull down, pull down, affinity chromatography technology, imaging technique, pull down, pull down, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, pull down, pull down, pull down, pull down, pull down, affinity chromatography technology, x-ray crystallography, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, imaging technique, imaging technique, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, imaging technique	Vinayagam A (2011), Vadlamudi RK (1996), Tanji K (2012), Matsumoto G (2011), Long J (2008), Long J (2008), Najat D (2009), Najat D (2009), Hocking LJ (2004), Boh BK (2011), Long J (2010), Seibenhener ML (2004), Seibenhener ML (2004), Seibenhener ML (2004), Fenner BJ (2009), Nathan JA (2013), Ciani B (2003), Shi J (2013), Goode A (2014), Bish RA (2007), Lu K (2014), Zhou L (2014), Zhou L (2014), Vadlamudi RK (1996), Long J (2008), Cavey JR (2006), Cavey JR (2006), Kirkin V (2009), Nakayasu ES (2013), Nakayasu ES (2013), Lim J (2015), Milan E (2015), Milan E (2015), Ordureau A (2015), Wurzer B (2015), Zhang X (2017), Wang L (2017), Liu X (2017), Peng H (2017), Donohue E (2014), Nibe Y (2017), Nibe Y (2017), Govindaraju VK (2017)	43
PARD6G	0	LLGL1	9	affinity chromatography technology	Brajenovic M (2004)	1
RIPK4	0	YWHAZ	1	affinity chromatography technology	Rodriguez J (2016)	1
HNRNPL	3	SMURF1	4	affinity chromatography technology	Fei T (2017)	1
CHUK	5	PRKCI	1	pull down, affinity chromatography technology, affinity chromatography technology	Lallena MJ (1999), Lallena MJ (1999), Lallena MJ (1999)	3
HSP90AA1	7	XPO1	8	affinity chromatography technology	Falsone SF (2005)	1
VHL	0	SQSTM1	0	affinity chromatography technology, affinity chromatography technology	Chen K (2016), Chen K (2016)	2
RHOJ	0	PRKCI	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
RIPK4	0	SQSTM1	0	affinity chromatography technology	Rodriguez J (2016)	1
YWHAH	0	MARK4	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brajenovic M (2004), Brajenovic M (2004), Brajenovic M (2004), Brajenovic M (2004)	4
AMOT	6	NIPSNAP2	1	bioid	Couzens AL (2013)	1
CASP8	1	SQSTM1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Pan JA (2011), Huang S (2013), Huang S (2013)	3
MAP1LC3B	1	SQSTM1	0	two hybrid, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, x-ray crystallography, affinity chromatography technology, x-ray crystallography, pull down, affinity chromatography technology, two hybrid, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Stelzl U (2005), Behrends C (2010), Vinayagam A (2011), Kirkin V (2009), Kirkin V (2009), Liang X (2013), Liang X (2013), Novak I (2010), Novak I (2010), Rogov VV (2012), Gao W (2013), Maruyama Y (2014), Maruyama Y (2014), Maruyama Y (2014), Yamashita SI (2014), Wurzer B (2015), Wurzer B (2015), Wurzer B (2015), Sun A (2017), Cohen-Kaplan V (2016), Dou Z (2015), Galindo-Moreno M (2017)	22
UBC	7	NPM1	0	affinity chromatography technology, pull down	Matsumoto M (2005), Koike A (2010)	2
HSP90AA1	7	TJP1	2	pull down	Wrighton KH (2008)	1
UBC	7	HNRNPL	3	affinity chromatography technology	Matsumoto M (2005)	1
PARD6B	0	RASSF8	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Hein MY (2015)	2
CEP135	2	SQSTM1	0	bioid	Gupta GD (2015)	1
ARHGEF16	1	PRKCI	1	affinity chromatography technology	Huttlin EL (2017)	1
DUSP1	1	IKBKB	1	affinity chromatography technology	Lallena MJ (1999)	1
RIPK4	0	YWHAE	0	affinity chromatography technology	Rodriguez J (2016)	1
APP	1	PARD6A	0	pull down	Virok DP (2011)	1
PARD6G	0	PARD6B	0	affinity chromatography technology	Brajenovic M (2004)	1
TRIM25	5	WWC1	5	affinity chromatography technology	Choudhury NR (2017)	1
PARD3	5	PARD6A	0	affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology	Kohjima M (2002), Brajenovic M (2004), Suzuki A (2001), Yang Z (2012), Hein MY (2015)	5
PDPK1	0	PRKCI	1	two hybrid, pull down	Balendran A (2000), Balendran A (2000)	2
FYN	1	HSP90AA1	7	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Loewenberg M (2006), Taipale M (2012), Taipale M (2012), Huttlin EL (2017)	4
TRIM25	5	SFPQ	2	affinity chromatography technology	Choudhury NR (2017)	1
PRKCZ	5	NIPSNAP2	1	affinity chromatography technology	Huttlin EL (2017)	1
CD44	1	FYN	1	biochemical, affinity chromatography technology	Ilangumaran S (1998), Ilangumaran S (1998)	2
RASSF8	2	APP	1	pull down	Olah J (2011)	1
XPO1	8	PDPK1	0	affinity chromatography technology	Kirli K (2015)	1
TSC22D1	1	PRKCI	1	two hybrid	Vinayagam A (2011)	1
PARD6B	0	PRKCI	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brajenovic M (2004), Brajenovic M (2004), Waaijers S (2013), Waaijers S (2013), Hayase J (2013), Rolland T (2014), Huttlin EL (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	10
DCAF7	4	SSB	0	genetic interference	Horlbeck MA (2018)	1
GABARAPL2	0	KBTBD7	3	two hybrid, affinity chromatography technology, pull down	Vinayagam A (2011), Genau HM (2015), Genau HM (2015)	3
TRIM25	5	GAPDH	0	affinity chromatography technology, affinity chromatography technology	Choudhury NR (2017), Choudhury NR (2017)	2
DUSP1	1	CHUK	5	affinity chromatography technology	Lallena MJ (1999)	1
HNRNPL	3	YWHAE	0	biochemical, affinity chromatography technology	Wan C (2015), Fei T (2017)	2
TMEM17	0	PRKCI	1	bioid	Gupta GD (2015)	1
ELAVL1	0	SFPQ	2	affinity chromatography technology	Abdelmohsen K (2009)	1
MAP1LC3B	1	UBC	7	imaging technique	Liu X (2017)	1
SQSTM1	0	MBP	0	pull down	Pridgeon JW (2004)	1
PARD6A	0	VHL	0	affinity chromatography technology, affinity chromatography technology	Schermer B (2006), Schermer B (2006)	2
IKBKG	0	CHUK	5	pull down, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, pull down, pull down, pull down, pull down, unspecified method, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology	Agou F (2002), Chen G (2002), Deng L (2000), Shifera AS (2008), Fenner BJ (2010), Rothwarf DM (1998), Rothwarf DM (1998), Hasegawa M (2008), Liu J (2009), Li S (2011), Li S (2011), Xia X (2011), Kensche T (2012), May MJ (2002), Wu ZH (2006), Wu ZH (2006), Palkowitsch L (2008), Le Page C (2001), Le Page C (2001), Huang TT (2002), Sebban-Benin H (2007), Tegethoff S (2003), Hai T (2006), Ammirante M (2010), McKenzie FR (2000), Solt LA (2007), Li XH (2001), Rottenberg S (2002), Poyet JL (2000), Poyet JL (2000), Stilo R (2004), Marienfeld RB (2006), Marienfeld RB (2006), Strnad J (2006), Strnad J (2006), Funakoshi-Tago M (2005), Shibata Y (2012), Wu X (2007), Stehlik C (2002), Ryzhakov G (2007), Chen RA (2008), Marinis JM (2012), Mitsuhashi S (2008), Mitsuhashi S (2008), Fujita H (2014), Lee SH (2012), Jackson SS (2014), Tokunaga F (2011), Criollo A (2010), Emmerich CH (2013), Liu D (2014), Hein MY (2015), Medunjanin S (2016), Huttlin EL (2017), Nowicka AM (2016), Rushe M (2008), Bal E (2017)	57
KERA	0	SQSTM1	0	affinity chromatography technology	Huttlin EL (2017)	1
TMEM17	0	NIPSNAP2	1	bioid	Gupta GD (2015)	1
PNMA1	0	PRKCI	1	affinity chromatography technology	Brajenovic M (2004)	1
PARD6G	0	PRKCZ	5	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Noda Y (2001), Brajenovic M (2004), So J (2015), Huttlin EL (2017)	4
UBC	7	AMOT	6	affinity chromatography technology	Matsumoto M (2005)	1
CD44	1	SQSTM1	0	affinity chromatography technology, affinity chromatography technology	Hein MY (2015), Huttlin EL (2017)	2
CHUK	5	CDC37	0	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chen G (2002), Li S (2011), Taipale M (2014), Taipale M (2014), Li J (2013)	5
HNRNPL	3	PARD3	5	affinity chromatography technology	Fei T (2017)	1
MAP1LC3B	1	GABARAPL2	0	pull down	Maruyama Y (2014)	1
PARD6A	0	LLGL2	4	affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology	Brajenovic M (2004), Hutchins JR (2010), Wan C (2015), Hein MY (2015), Hein MY (2015)	5
ELAVL1	0	XPO1	8	affinity chromatography technology	Abdelmohsen K (2009)	1
NPM1	0	NIPSNAP1	3	affinity chromatography technology	Chen R (2013)	1
NPM1	0	PARD6B	0	affinity chromatography technology	Chen R (2013)	1
FABP4	3	PRKCI	1	two hybrid	Vinayagam A (2011)	1
YWHAH	0	PARD6A	0	affinity chromatography technology	Brajenovic M (2004)	1
HNRNPL	3	SFPQ	2	biochemical	Havugimana PC (2012)	1
XPO1	8	CHUK	5	affinity chromatography technology	Kirli K (2015)	1
YWHAH	0	PRKCI	1	affinity chromatography technology, affinity chromatography technology	Brajenovic M (2004), Brajenovic M (2004)	2
PRKCZ	5	PRKCI	1	affinity chromatography technology, affinity chromatography technology	So J (2015), Huttlin EL (2017)	2
CD44	1	PRKCZ	5	affinity chromatography technology	Park D (2012)	1
XPO1	8	TJP1	2	affinity chromatography technology	Kirli K (2015)	1
HNRNPL	3	FARP2	1	affinity chromatography technology	Fei T (2017)	1
WWC1	5	PRKCZ	5	two hybrid, pull down, enzymatic study, affinity chromatography technology	Buether K (2004), Buether K (2004), Buether K (2004), Huttlin EL (2017)	4
MAP2K5	1	CD44	1	fluorescent resonance energy transfe	Ivanov AA (2017)	1
MAP1LC3A	0	CASP8	1	affinity chromatography technology, affinity chromatography technology	Pan JA (2011), Pan JA (2011)	2
PARD3	5	PNMA1	0	affinity chromatography technology, affinity chromatography technology	Brajenovic M (2004), Brajenovic M (2004)	2
NPM1	0	LLGL1	9	affinity chromatography technology	Chen R (2013)	1
MAP1LC3A	0	NIPSNAP2	1	affinity chromatography technology	Behrends C (2010)	1
LLGL2	4	KBTBD7	3	affinity chromatography technology, affinity chromatography technology	Hauri S (2013), Huttlin EL (2017)	2
CEP135	2	TJP1	2	bioid	Gupta GD (2015)	1
XPO1	8	GABARAPL1	0	affinity chromatography technology	Kirli K (2015)	1
IKBKG	0	CDC37	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bouwmeester T (2004), Chen G (2002), Taipale M (2014), Taipale M (2014), Liu D (2014), Hein MY (2015), Hein MY (2015), Li J (2013)	8
MAP1LC3A	0	UBC	7	biochemical, imaging technique	Fujita N (2013), Govindaraju VK (2017)	2
MAP2K5	1	CDC37	0	affinity chromatography technology	Huttlin EL (2017)	1
TRIM25	5	DCAF7	4	affinity chromatography technology	Choudhury NR (2017)	1
YWHAZ	1	PARD3	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brajenovic M (2004), Brajenovic M (2004), Brajenovic M (2004)	3
BAD	1	YWHAE	0	two hybrid, two hybrid, pull down, affinity chromatography technology, two hybrid	Hsu SY (1997), Bandyopadhyay S (2010), Subramanian RR (2001), Gloeckner CJ (2007), Wang J (2011)	5
PRKCI	1	BAD	1	pull down	Jin Z (2005)	1
PARD3	5	LLGL1	9	affinity chromatography technology	Brajenovic M (2004)	1
XPO1	8	SQSTM1	0	affinity chromatography technology	Kirli K (2015)	1
NPM1	0	HSP90AA1	7	affinity chromatography technology	Chen R (2013)	1
PARD6B	0	KBTBD7	3	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
ELAVL1	0	SMG1	7	affinity chromatography technology	Abdelmohsen K (2009)	1
PRKCI	1	SMG1	7	two hybrid, pull down, affinity chromatography technology	Diaz-Meco MT (1996), Diaz-Meco MT (1996), Diaz-Meco MT (1996)	3
MARK2	6	PRKCI	1	affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Suzuki A (2004)	2
ELAVL1	0	GABARAPL2	0	affinity chromatography technology	Abdelmohsen K (2009)	1
IKBKG	0	KIF23	0	affinity chromatography technology	Simon GC (2008)	1
YWHAE	0	RASSF8	2	affinity chromatography technology	Gloeckner CJ (2007)	1
YWHAH	0	PARD6B	0	affinity chromatography technology, affinity chromatography technology	Brajenovic M (2004), Hein MY (2015)	2
TRIM25	5	CD44	1	affinity chromatography technology	Choudhury NR (2017)	1
ELAVL1	0	CHUK	5	affinity chromatography technology	Chu PC (2012)	1
MAP1LC3B	1	CASP8	1	two hybrid	Vinayagam A (2011)	1
MARK2	6	MARK4	6	affinity chromatography technology	Sowa ME (2009)	1
YWHAZ	1	BAD	1	pull down, two hybrid, two hybrid, affinity chromatography technology, pull down, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yang H (2001), Yang H (2001), Bandyopadhyay S (2010), Liang X (2010), Subramanian RR (2001), Polzien L (2009), Wang J (2011), Jin L (2009), Mortenson JB (2015), Dong S (2007)	10
PPM1B	2	IKBKB	1	affinity chromatography technology, affinity chromatography technology, enzymatic study	Prajapati S (2004), Prajapati S (2004), Prajapati S (2004)	3
PRKCI	1	MARK4	6	affinity chromatography technology, affinity chromatography technology, enzymatic study	Brajenovic M (2004), Brajenovic M (2004), Naz F (2015)	3
PRKCI	1	TRAPPC13	0	affinity chromatography technology	Hein MY (2015)	1
VHL	0	HSP90AA1	7	affinity chromatography technology, genetic interference	Yang C (2013), Shen JP (2017)	2
RAPGEF2	5	TJP1	2	affinity chromatography technology	Kim TY (2014)	1
USP21	2	XPO1	8	imaging technique	Garcia-Santisteban I (2012)	1
PRKCZ	5	MBP	0	enzymatic study, enzymatic study	Pillai P (2011), Lerner-Marmarosh N (2007)	2
MARK4	6	PNMA1	0	affinity chromatography technology	Brajenovic M (2004)	1
PDPK1	0	PRKCZ	5	two hybrid, two hybrid, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, pull down	Balendran A (2000), Hodgkinson CP (2002), Hodgkinson CP (2002), Le Good JA (1998), Le Good JA (1998), Le Good JA (1998), Balendran A (2000), Park J (1999)	8
PDGFD	1	PRKCI	1	affinity chromatography technology	Huttlin EL (2017)	1
YWHAZ	1	MARK2	6	affinity chromatography technology	Brajenovic M (2004)	1
CDK7	0	APP	1	pull down	Olah J (2011)	1
GABARAPL1	0	PRKCI	1	affinity chromatography technology	Behrends C (2010)	1
TRIM25	5	HNRNPL	3	affinity chromatography technology	Choudhury NR (2017)	1
SMURF1	4	PPM1A	1	affinity chromatography technology	Xie Y (2013)	1
WWC1	5	YWHAE	0	affinity chromatography technology	Hauri S (2013)	1
GAPDH	0	YWHAE	0	two hybrid	Vinayagam A (2011)	1
GABARAPL1	0	LLGL1	9	affinity chromatography technology	Behrends C (2010)	1
SQSTM1	0	MAP2K5	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down	Nakamura K (2010), Nakamura K (2010), Nakamura K (2010), Lamark T (2003), Lamark T (2003), Lamark T (2003)	6
SQSTM1	0	PRKCZ	5	affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, affinity chromatography technology, imaging technique, affinity chromatography technology	Sanz L (2000), Hirano Y (2004), Chang S (2002), Wilson MI (2003), Feng Y (2005), Kim GY (2012), Urbanczyk A (2011), Linares JF (2011), So J (2015), Tsai LC (2015), Huttlin EL (2017), Tobias IS (2016), Tobias IS (2016)	13
YWHAZ	1	PARD6A	0	affinity chromatography technology	Brajenovic M (2004)	1
RASSF8	2	PRKCI	1	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
CEP135	2	YWHAH	0	bioid	Gupta GD (2015)	1
PRKCI	1	SSB	0	affinity chromatography technology	Hein MY (2015)	1
PRKCI	1	ZNF609	4	affinity chromatography technology	Hein MY (2015)	1
ADAP1	3	PRKCI	1	affinity chromatography technology, pull down	Zemlickova E (2003), Zemlickova E (2003)	2
SQSTM1	0	GABARAPL2	0	two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid	Rual JF (2005), Behrends C (2010), Vinayagam A (2011), Shvets E (2011), Kirkin V (2009), Kirkin V (2009), Maruyama Y (2014), Rolland T (2014), Yu H (2011)	9
PRKCI	1	APP	1	pull down	Olah J (2011)	1
HSP90AA1	7	CHUK	5	affinity chromatography technology, affinity chromatography technology	Qu X (2012), Gano JJ (2010)	2
YWHAE	0	CDC37	0	affinity chromatography technology	Zuo S (2010)	1
MARK2	6	YWHAH	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Brajenovic M (2004), Brajenovic M (2004), Brajenovic M (2004)	4
PRKCI	1	RAPGEF2	5	affinity chromatography technology	Brajenovic M (2004)	1
SFPQ	2	PRKCI	1	affinity chromatography technology	Denner L (2010)	1
XPO1	8	PPM1B	2	affinity chromatography technology	Kirli K (2015)	1
PRKCI	1	NIPSNAP1	3	affinity chromatography technology	Brajenovic M (2004)	1
TMEM17	0	FRS2	0	bioid	Gupta GD (2015)	1
TRIM25	5	SQSTM1	0	affinity chromatography technology	Choudhury NR (2017)	1
DUSP1	1	PRKCI	1	affinity chromatography technology	Lallena MJ (1999)	1
PRKCI	1	TMEM208	0	affinity chromatography technology	Hein MY (2015)	1
PRKCZ	5	YWHAH	0	affinity chromatography technology	Van Der Hoeven PC (2000)	1
WWC1	5	YWHAH	0	affinity chromatography technology	Hauri S (2013)	1
SQSTM1	0	YWHAZ	1	pull down	Pridgeon JW (2004)	1
PARD6B	0	PRKCZ	5	two hybrid, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Noda Y (2001), Noda Y (2001), Brajenovic M (2004), Wilson MI (2003), So J (2015), Huttlin EL (2015), Huttlin EL (2017)	7
YWHAZ	1	PNMA1	0	affinity chromatography technology	Brajenovic M (2004)	1
YWHAZ	1	UBC	7	affinity chromatography technology	Jin J (2004)	1
USP21	2	PRKCI	1	affinity chromatography technology	Sowa ME (2009)	1
MAP1LC3A	0	PRKCI	1	affinity chromatography technology	Behrends C (2010)	1
YWHAE	0	PPM1B	2	affinity chromatography technology, affinity chromatography technology	Zuo S (2010), Zuo S (2010)	2
TRIM25	5	YWHAZ	1	affinity chromatography technology	Choudhury NR (2017)	1
CD44	1	PRKCI	1	affinity chromatography technology	Huttlin EL (2017)	1
IKBKB	1	CASP8	1	affinity chromatography technology	Chaudhary PM (2000)	1
MAP1LC3A	0	SQSTM1	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, biochemical, imaging technique, affinity chromatography technology, x-ray crystallography, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down, pull down, affinity chromatography technology	Shvets E (2008), Shvets E (2008), Behrends C (2010), Gao Z (2010), Pan JA (2011), Pankiv S (2007), Pankiv S (2007), Shvets E (2011), Tung YT (2010), Bjorkoy G (2005), Kirkin V (2009), Lim J (2011), Lim J (2011), Pan JA (2012), Lee DY (2013), Wang BS (2013), Wang BS (2013), Sansanwal P (2012), Shi J (2013), Fujita N (2013), Chen X (2014), Liu XD (2014), Noda NN (2008), Noda NN (2008), Matsuzawa Y (2015), Matsuzawa Y (2015), Rui YN (2015), Rui YN (2015), Ciuffa R (2015), Wang N (2013), Hua F (2015), Rui YN (2015), Cha-Molstad H (2015), Paul S (2012), Puvirajesinghe TM (2016), Wang L (2017), Cha-Molstad H (2017), Peng H (2017), Lee Y (2017)	39
ARHGAP17	1	PARD3	5	affinity chromatography technology	Wells CD (2006)	1
YWHAH	0	DCAF7	4	affinity chromatography technology	Brajenovic M (2004)	1
PDPK1	0	APP	1	pull down	Olah J (2011)	1
GABARAPL2	0	YWHAZ	1	two hybrid	Vinayagam A (2011)	1
MAP1LC3B	1	NIPSNAP1	3	affinity chromatography technology	Behrends C (2010)	1
TRIM25	5	XPO1	8	affinity chromatography technology	Choudhury NR (2017)	1
VHL	0	UBC	7	pull down	Lisztwan J (1999)	1
XPO1	8	MAGED2	1	affinity chromatography technology	Kirli K (2015)	1
SQSTM1	0	LLGL1	9	affinity chromatography technology	Behrends C (2010)	1
SFPQ	2	UBC	7	two hybrid, two hybrid, affinity chromatography technology, pull down	Stelzl U (2005), Stelzl U (2005), Matsumoto M (2005), Nathan JA (2013)	4
ELAVL1	0	TJP1	2	affinity chromatography technology	Abdelmohsen K (2009)	1
PRKCI	1	NIPSNAP2	1	affinity chromatography technology	Brajenovic M (2004)	1
CDC37	0	SSB	0	biochemical	Wan C (2015)	1
NPM1	0	APP	1	pull down	Olah J (2011)	1
HNRNPL	3	ARHGEF16	1	affinity chromatography technology	Fei T (2017)	1
PRKCI	1	CDK7	0	enzymatic study	Pillai P (2011)	1
ELAVL1	0	LLGL1	9	affinity chromatography technology	Abdelmohsen K (2009)	1
RIPK4	0	PRKCI	1	affinity chromatography technology	Rodriguez J (2016)	1
SSB	0	APP	1	pull down	Olah J (2011)	1
MAP1LC3A	0	APP	1	pull down	Olah J (2011)	1
PRKCZ	5	HSP90AA1	7	two hybrid, affinity chromatography technology, affinity chromatography technology	Bandyopadhyay S (2010), Taipale M (2012), Taipale M (2012)	3
UBC	7	CDK7	0	imaging technique	Zhang X (2017)	1
HSP90AA1	7	GAPDH	0	affinity chromatography technology, biochemical	Falsone SF (2005), Wan C (2015)	2
YWHAZ	1	PRKCI	1	pull down, affinity chromatography technology	Zemlickova E (2003), Brajenovic M (2004)	2
BAD	1	YWHAH	0	two hybrid, pull down, two hybrid	Hsu SY (1997), Subramanian RR (2001), Wang J (2011)	3
RAPGEF2	5	UBC	7	affinity chromatography technology	Kim TY (2014)	1
TRIM25	5	YWHAE	0	affinity chromatography technology	Choudhury NR (2017)	1
NIPSNAP2	1	NIPSNAP1	3	affinity chromatography technology, affinity chromatography technology	Behrends C (2010), Hein MY (2015)	2
PRKCZ	5	LLGL2	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	So J (2015), Hauri S (2013), Huttlin EL (2017)	3
GABARAPL2	0	PRKCI	1	affinity chromatography technology	Behrends C (2010)	1
XPO1	8	RAPGEF2	5	affinity chromatography technology	Kirli K (2015)	1
CD44	1	NIPSNAP2	1	affinity chromatography technology	Huttlin EL (2017)	1
ARHGAP17	1	APP	1	pull down	Olah J (2011)	1
GABARAPL1	0	NIPSNAP1	3	affinity chromatography technology	Behrends C (2010)	1
ARHGAP17	1	AMOT	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Wells CD (2006), Wells CD (2006), Wells CD (2006)	3
HSP90AA1	7	KBTBD7	3	affinity chromatography technology	Taipale M (2012)	1
PARD6B	0	PARD6A	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brajenovic M (2004), Brajenovic M (2004), Hein MY (2015)	3
PRKCI	1	CDC37	0	affinity chromatography technology	Brajenovic M (2004)	1
PRKCI	1	LLGL1	9	affinity chromatography technology, biochemical, affinity chromatography technology	Brajenovic M (2004), Wan C (2015), Hein MY (2015)	3
ELAVL1	0	SSB	0	affinity chromatography technology	Abdelmohsen K (2009)	1
PARD6B	0	LLGL2	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brajenovic M (2004), Hutchins JR (2010), Huttlin EL (2015), Hauri S (2013), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	7
PRKCI	1	MASTL	5	affinity chromatography technology	Hein MY (2015)	1
PARD3	5	MARK2	6	affinity chromatography technology	Yang Z (2012)	1
PARD6B	0	APP	1	pull down	Olah J (2011)	1
SMURF1	4	APP	1	pull down	Olah J (2011)	1
GAPDH	0	APP	1	pull down, pull down	Olah J (2011), Virok DP (2011)	2
SMURF1	4	SSB	0	affinity chromatography technology	Xie Y (2013)	1
SMG1	7	HSP90AA1	7	affinity chromatography technology	Izumi N (2010)	1
MAP2K5	1	YWHAZ	1	two hybrid	Bandyopadhyay S (2010)	1
ARHGAP17	1	PRKCI	1	affinity chromatography technology	Wells CD (2006)	1
YWHAZ	1	YWHAH	0	biochemical, biochemical, affinity chromatography technology, affinity chromatography technology	Kristensen AR (2012), Wan C (2015), Hein MY (2015), Hein MY (2015)	4
ELAVL1	0	HNRNPL	3	affinity chromatography technology	Abdelmohsen K (2009)	1
GABARAPL2	0	APP	1	pull down	Olah J (2011)	1
HNRNPL	3	TSC22D1	1	affinity chromatography technology	Fei T (2017)	1
XPO1	8	DCAF7	4	affinity chromatography technology	Kirli K (2015)	1
PARD6G	0	MARK2	6	affinity chromatography technology	Brajenovic M (2004)	1
PRKCI	1	KIF23	0	biochemical	Wan C (2015)	1
GABARAPL1	0	KBTBD7	3	affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, unspecified method	Behrends C (2010), Rolland T (2014), Genau HM (2015), Genau HM (2015), Genau HM (2015)	5
TRIM25	5	4651	0	affinity chromatography technology	Choudhury NR (2017)	1
CDC37	0	CDK7	0	pull down, affinity chromatography technology	Stepanova L (1996), Huttlin EL (2015)	2
ARHGAP17	1	PARD6A	0	affinity chromatography technology	Wells CD (2006)	1
TRIM25	5	FARP2	1	affinity chromatography technology	Choudhury NR (2017)	1
TRIM25	5	FRS2	0	affinity chromatography technology	Choudhury NR (2017)	1
MTMR4	1	PRKCI	1	bioid	St-Denis N (2016)	1
TMEM17	0	MARK2	6	bioid	Gupta GD (2015)	1
PRKCZ	5	LLGL1	9	affinity chromatography technology, affinity chromatography technology	So J (2015), Huttlin EL (2017)	2
VHL	0	PARD3	5	affinity chromatography technology	Schermer B (2006)	1
XPO1	8	4651	0	affinity chromatography technology	Kirli K (2015)	1
YWHAZ	1	YWHAE	0	two hybrid, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, two hybrid, biochemical, biochemical, affinity chromatography technology, pull down	Bandyopadhyay S (2010), Zippo A (2009), Zippo A (2009), Havugimana PC (2012), Gloeckner CJ (2007), Wang J (2011), Kristensen AR (2012), Wan C (2015), Hein MY (2015), Gu YM (2006)	10
HNRNPL	3	PRKCZ	5	affinity chromatography technology	Fei T (2017)	1
GAB1	3	FRS2	0	affinity chromatography technology	Zhou L (2015)	1
FYN	1	PRKCI	1	affinity chromatography technology	Huttlin EL (2017)	1
PARD6B	0	LLGL1	9	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brajenovic M (2004), Huttlin EL (2015), Hein MY (2015), Hein MY (2015), Huttlin EL (2017)	5
IKBKB	1	HSP90AA1	7	affinity chromatography technology	Xue J (2010)	1
YWHAE	0	PRKCI	1	affinity chromatography technology	Gloeckner CJ (2007)	1
YWHAZ	1	DCAF7	4	affinity chromatography technology	Brajenovic M (2004)	1
PARD3	5	TJP1	2	imaging technique	Suzuki A (2001)	1
AMOT	6	PRKCI	1	bioid	Couzens AL (2013)	1
IKBKB	1	CDC37	0	biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chen G (2002), Chen G (2002), Li S (2011), Taipale M (2014), Taipale M (2014), Hein MY (2015)	6
HNRNPL	3	NGEF	1	affinity chromatography technology	Fei T (2017)	1
YWHAZ	1	XPO1	8	affinity chromatography technology	Hein MY (2015)	1
XPO1	8	NIPSNAP1	3	affinity chromatography technology	Kirli K (2015)	1
MAP2K5	1	PRKCZ	5	affinity chromatography technology, affinity chromatography technology, pull down	Diaz-Meco MT (2001), Diaz-Meco MT (2001), Diaz-Meco MT (2001)	3
TRIM25	5	PARD3	5	affinity chromatography technology	Choudhury NR (2017)	1
YWHAZ	1	KIF23	0	affinity chromatography technology	Brajenovic M (2004)	1
NPM1	0	YWHAZ	1	affinity chromatography technology	Chen R (2013)	1
ADAP1	3	PRKCZ	5	affinity chromatography technology, pull down, enzymatic study	Zemlickova E (2003), Zemlickova E (2003), Zemlickova E (2003)	3
YWHAE	0	NPM1	0	affinity chromatography technology, affinity chromatography technology	Zuo S (2010), Chen R (2013)	2
MTMR4	1	YWHAH	0	affinity chromatography technology	Li X (2016)	1
PARD6B	0	WWC1	5	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
YWHAE	0	PARD3	5	affinity chromatography technology	Gloeckner CJ (2007)	1
USP21	2	MARK2	6	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Sowa ME (2009), Urbe S (2012), Urbe S (2012)	3
PPM1A	1	PPM1B	2	affinity chromatography technology, affinity chromatography technology	Huttlin EL (2015), Huttlin EL (2017)	2
XPO1	8	PRKCI	1	affinity chromatography technology	Kirli K (2015)	1
SMURF1	4	PARD6A	0	affinity chromatography technology, affinity chromatography technology	Cheng PL (2011), Ozdamar B (2005)	2
FGB	2	PRKCI	1	affinity chromatography technology	Huttlin EL (2017)	1
PARD3	5	GAB1	3	affinity chromatography technology, affinity chromatography technology	Yang Z (2012), Yang Z (2012)	2
MAP2K5	1	PRKCI	1	affinity chromatography technology, affinity chromatography technology	Lamark T (2003), Lamark T (2003)	2
TRIM25	5	PRKCI	1	affinity chromatography technology	Choudhury NR (2017)	1
XPO1	8	EIF4ENIF1	1	affinity chromatography technology	Kirli K (2015)	1
KBTBD7	3	LLGL1	9	affinity chromatography technology, affinity chromatography technology	Behrends C (2010), Huttlin EL (2017)	2
PARD6G	0	LLGL2	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brajenovic M (2004), Hauri S (2013), Huttlin EL (2017)	3
YWHAE	0	YWHAH	0	two hybrid, affinity chromatography technology, biochemical, biochemical, affinity chromatography technology	Bandyopadhyay S (2010), Gloeckner CJ (2007), Kristensen AR (2012), Wan C (2015), Hein MY (2015)	5
PARD6A	0	MARK2	6	affinity chromatography technology	Brajenovic M (2004)	1
MAP1LC3B	1	NIPSNAP2	1	affinity chromatography technology	Behrends C (2010)	1
MTMR4	1	YWHAZ	1	affinity chromatography technology	Li X (2016)	1
HSP90AA1	7	LLGL1	9	genetic interference	Srivas R (2016)	1
PARD6G	0	PRKCI	1	affinity chromatography technology, affinity chromatography technology	Brajenovic M (2004), Brajenovic M (2004)	2
PRKCI	1	MAGED2	1	affinity chromatography technology	Hein MY (2015)	1
PARD6A	0	RASSF8	2	affinity chromatography technology	Hein MY (2015)	1
FYN	1	CDC37	0	affinity chromatography technology	Huttlin EL (2017)	1
PARD6A	0	TJP1	2	imaging technique	Suzuki A (2001)	1
ELAVL1	0	CD44	1	affinity chromatography technology	Abdelmohsen K (2009)	1
MAP1LC3B	1	KBTBD7	3	two hybrid, two hybrid, affinity chromatography technology, pull down, unspecified method	Stelzl U (2005), Vinayagam A (2011), Genau HM (2015), Genau HM (2015), Genau HM (2015)	5
AMOT	6	WWC1	5	bioid, affinity chromatography technology, affinity chromatography technology	Couzens AL (2013), Hauri S (2013), Toloczko A (2017)	3
XPO1	8	FARP2	1	affinity chromatography technology	Kirli K (2015)	1
RIPK4	0	IKBKG	0	affinity chromatography technology	Rodriguez J (2016)	1
PDPK1	0	YWHAH	0	affinity chromatography technology, pull down	Sato S (2002), Sato S (2002)	2
IL1RAP	3	PRKCI	1	two hybrid	Wang J (2011)	1
PRKCI	1	PPM1A	1	biochemical	Wan C (2015)	1
TTR	0	PRKCI	1	two hybrid	Vinayagam A (2011)	1
PRKCI	1	PARD6A	0	two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, pull down, two hybrid, two hybrid, affinity chromatography technology	Rual JF (2005), Brajenovic M (2004), Suzuki A (2001), Suzuki A (2001), Suzuki A (2001), Lamark T (2003), Lamark T (2003), Lamark T (2003), Lamark T (2003), Erdogan E (2006), Rolland T (2014), Yu H (2011), Hein MY (2015)	13
UBC	7	IKBKG	0	pull down, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, x-ray crystallography, pull down, unspecified method, x-ray crystallography, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down, x-ray crystallography, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, two hybrid, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Dynek JN (2010), Dynek JN (2010), Chiaravalli J (2011), Laplantine E (2009), Hubeau M (2011), Lo YC (2009), Ikeda F (2010), Cordier F (2009), Cordier F (2009), Cordier F (2009), Renner F (2011), Fenner BJ (2009), Fenner BJ (2009), Ivins FJ (2009), Rahighi S (2009), Rahighi S (2009), Zhu G (2007), Zhu G (2007), Niu J (2011), Keusekotten K (2013), van Wijk SJ (2013), Hooper C (2014), Wagner S (2008), Saul VV (2014), Gleason CE (2011), Komander D (2009), Kensche T (2012), Skaug B (2011), Ea CK (2006), Ea CK (2006), Lo YC (2009), Laplantine E (2009), Laplantine E (2009), Emmerich CH (2013), Dubosclard V (2015), Vincendeau M (2015), Vincendeau M (2016), Zhang X (2017), Fang R (2017), Kliza K (2017), Joo D (2016), Fang R (2017), Hauenstein AV (2017)	43
YWHAE	0	KIF23	0	affinity chromatography technology	Gloeckner CJ (2007)	1
PARD6A	0	LLGL1	9	affinity chromatography technology, affinity chromatography technology	Brajenovic M (2004), Hein MY (2015)	2
CASP8	1	UBC	7	pull down	Bellail AC (2012)	1
UBC	7	CHUK	5	pull down	Zhang X (2017)	1
MAP1LC3A	0	GABARAPL1	0	imaging technique	Tanida I (2006)	1
DCAF7	4	APP	1	pull down	Olah J (2011)	1
TMEM17	0	LLGL1	9	bioid	Gupta GD (2015)	1
TMEM17	0	SQSTM1	0	bioid	Gupta GD (2015)	1
ELAVL1	0	YWHAH	0	affinity chromatography technology	Abdelmohsen K (2009)	1
RHOJ	0	PARD6B	0	two hybrid, affinity chromatography technology, affinity chromatography technology	Rolland T (2014), Huttlin EL (2015), Huttlin EL (2017)	3
SQSTM1	0	NIPSNAP1	3	affinity chromatography technology	Behrends C (2010)	1
IKBKG	0	SQSTM1	0	affinity chromatography technology, affinity chromatography technology	Martin P (2006), Zotti T (2014)	2
PARD3	5	PARD6G	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kohjima M (2002), Brajenovic M (2004), Brajenovic M (2004)	3
PARD3	5	DCAF7	4	affinity chromatography technology, affinity chromatography technology	Brajenovic M (2004), Boldt K (2016)	2
YWHAE	0	XPO1	8	biochemical	Kristensen AR (2012)	1
SMURF1	4	MARK2	6	enzymatic study	Andrews PS (2010)	1
MAP1LC3A	0	NIPSNAP1	3	affinity chromatography technology	Behrends C (2010)	1
KBTBD7	3	TJP1	2	affinity chromatography technology, affinity chromatography technology	Behrends C (2010), Huttlin EL (2017)	2
FYN	1	IKBKG	0	affinity chromatography technology	Lee SH (2012)	1
HSP90AA1	7	CDC37	0	x-ray crystallography, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Roe SM (2004), Silverstein AM (1998), Mollapour M (2010), Basso AD (2002), Tsutsumi S (2012), De Nardo D (2005), Sarkar S (2012), Gano JJ (2010), Taipale M (2012), Skarra DV (2011), Zhang H (2004), Taipale M (2014), Taipale M (2014), Mollapour M (2014), Hein MY (2015), Hein MY (2015), Li J (2013), Woodford MR (2016), Shao J (2003), Scholz GM (2001), Sun L (2012), Sun L (2012), Woodford MR (2016), Synoradzki K (2015)	24
IKBKB	1	CHUK	5	affinity chromatography technology, biochemical, biochemical, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, enzymatic study, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology, biochemical, affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology	Zandi E (1997), Chen G (2002), Otsuki T (2002), May MJ (2000), May MJ (2000), Woronicz JD (1997), Woronicz JD (1997), Deng L (2000), Yeung KC (2001), Mercurio F (1997), Mercurio F (1997), Rothwarf DM (1998), Wu ZH (2010), Li S (2011), Li S (2011), May MJ (2002), Heilker R (1999), Leotoing L (2011), McKenzie FR (2000), Zandi E (1998), Lee DF (2007), Li XH (2001), Yeh PY (2011), Yeh PY (2011), Stehlik C (2002), Li Q (2006), So J (2015), Chen TC (2014), Karim ZA (2015), Huttlin EL (2017)	30
PRKCI	1	LLGL2	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brajenovic M (2004), Hutchins JR (2010), Hauri S (2013), Hein MY (2015), Huttlin EL (2017)	5
PPM1B	2	CHUK	5	affinity chromatography technology, affinity chromatography technology, imaging technique	Prajapati S (2004), Prajapati S (2004), Chen TC (2014)	3
IKBKG	0	PRKCI	1	two hybrid	Wang J (2011)	1
TRIM25	5	UBC	7	enzymatic study	Sanchez JG (2016)	1
PRKCI	1	EIF4ENIF1	1	affinity chromatography technology	Hein MY (2015)	1
PRKCI	1	MBP	0	enzymatic study	Pillai P (2011)	1
PRKCI	1	PPM1B	2	biochemical	Wan C (2015)	1
YWHAH	0	KIF23	0	affinity chromatography technology, affinity chromatography technology	Brajenovic M (2004), Hein MY (2015)	2
PARD3	5	PARD6B	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kohjima M (2002), Brajenovic M (2004), Brajenovic M (2004), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	6
WWC1	5	PRKCI	1	affinity chromatography technology	Toloczko A (2017)	1
PARD3	5	PRKCZ	5	affinity chromatography technology	Kohjima M (2002)	1
CASP8	1	VHL	0	genetic interference	Shen JP (2017)	1
GABARAPL1	0	GABARAPL2	0	affinity chromatography technology	Behrends C (2010)	1
IKBKB	1	PRKCI	1	pull down, affinity chromatography technology, affinity chromatography technology	Lallena MJ (1999), Lallena MJ (1999), Lallena MJ (1999)	3
PARD3	5	AMOT	6	affinity chromatography technology	Wells CD (2006)	1
PARD3	5	RASSF8	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Brajenovic M (2004), Huttlin EL (2015), Hein MY (2015), Huttlin EL (2017)	4
GAB1	3	MARK2	6	affinity chromatography technology, affinity chromatography technology, pull down	Yang Z (2012), Yang Z (2012), Yang Z (2012)	3
LLGL2	4	SQSTM1	0	affinity chromatography technology	Hauri S (2013)	1
NGEF	1	PRKCI	1	affinity chromatography technology	Huttlin EL (2017)	1
IKBKB	1	IKBKG	0	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, biochemical, unspecified method, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, x-ray crystallography, pull down, affinity chromatography technology	Chen G (2002), Chen G (2002), Chariot A (2002), Wu RC (2002), Deng L (2000), Shifera AS (2008), Fenner BJ (2010), Fenner BJ (2010), Fenner BJ (2010), Lee KY (2005), Rothwarf DM (1998), Ea CK (2006), Thurston TL (2009), Orel L (2010), Wu ZH (2010), Napolitano G (2009), Liu J (2009), Skaug B (2011), Li S (2011), Li S (2011), Kensche T (2012), Chiaravalli J (2011), Wu CJ (2006), Wu ZH (2006), Ahmad R (2007), Ahmad R (2007), Palkowitsch L (2008), Palkowitsch L (2008), Lo YC (2008), Mabb AM (2006), Baima ET (2010), Tegethoff S (2003), Tegethoff S (2003), Hai T (2006), Ammirante M (2010), Lee DF (2007), Rottenberg S (2002), Poyet JL (2000), Stilo R (2004), Marienfeld RB (2006), Marienfeld RB (2006), Strnad J (2006), Funakoshi-Tago M (2005), Ivins FJ (2009), Shibata Y (2012), Shibata Y (2012), Wu X (2007), Stehlik C (2002), Ryzhakov G (2007), Chen RA (2008), Wu ZH (2008), Mitsuhashi S (2008), Fujita H (2014), Golden MS (2013), Lee SH (2012), Cote SM (2013), Kim HJ (2014), Jackson SS (2014), Liao W (2008), Tokunaga F (2011), Criollo A (2010), Emmerich CH (2013), So J (2015), Liu D (2014), Guo B (2014), Guo B (2014), Guo B (2014), Zhou L (2014), Zhou L (2014), Hein MY (2015), Bagneris C (2015), Medunjanin S (2016), Huttlin EL (2017), Nowicka AM (2016), Rushe M (2008), Rushe M (2008), Hauenstein AV (2017), Bal E (2017)	78
XPO1	8	WWC1	5	affinity chromatography technology	Kirli K (2015)	1
PRKCI	1	GAB1	3	affinity chromatography technology	Yang Z (2012)	1
PRKCI	1	GAPDH	0	enzymatic study, affinity chromatography technology	Tisdale EJ (2002), Tisdale EJ (2002)	2
PRKCZ	5	PARD6A	0	two hybrid, pull down, two hybrid, affinity chromatography technology, two hybrid, two hybrid, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Rual JF (2005), Liu XF (2004), Noda Y (2001), Brajenovic M (2004), Lamark T (2003), Lamark T (2003), So J (2015), Huttlin EL (2017), Tobias IS (2016), Tobias IS (2016)	10
VHL	0	PRKCZ	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Okuda H (1999), Okuda H (1999), Schermer B (2006)	3
HSP90AA1	7	MAP2K5	1	affinity chromatography technology	Taipale M (2012)	1
SMURF1	4	VHL	0	affinity chromatography technology	Zhang C (2016)	1
SQSTM1	0	GABARAPL1	0	two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, imaging technique, two hybrid	Rual JF (2005), Behrends C (2010), Wild P (2011), Kirkin V (2009), Zhang Y (2011), Zhang Y (2011), Rolland T (2014)	7
GPR156	2	PRKCI	1	affinity chromatography technology	Huttlin EL (2017)	1
MARK2	6	YWHAE	0	affinity chromatography technology, affinity chromatography technology	Goeransson O (2006), Gloeckner CJ (2007)	2
ELAVL1	0	MTMR4	1	affinity chromatography technology	Abdelmohsen K (2009)	1
CDK7	0	MBP	0	enzymatic study	Pinhero R (2004)	1
USP21	2	UBC	7	enzymatic study, enzymatic study, pull down, enzymatic study, enzymatic study, unspecified method, enzymatic study, enzymatic study, pull down, enzymatic study	Bremm A (2010), Faesen AC (2011), Ye Y (2011), Urbe S (2012), Loch CM (2012), Ernst A (2013), Ye Y (2011), Wauer T (2015), Leung I (2016), Michel MA (2017)	10
MAP1LC3B	1	MAP1LC3A	0	affinity chromatography technology	Behrends C (2010)	1
TRIM25	5	MAGED2	1	affinity chromatography technology	Choudhury NR (2017)	1
VHL	0	PPM1B	2	affinity chromatography technology	Lai Y (2011)	1
NPM1	0	PRKCI	1	affinity chromatography technology	Chen R (2013)	1
RIPK4	0	YWHAH	0	affinity chromatography technology	Rodriguez J (2016)	1
RIPK4	0	XPO1	8	affinity chromatography technology	Rodriguez J (2016)	1
PPM1B	2	IKBKG	0	affinity chromatography technology, affinity chromatography technology	Prajapati S (2004), Prajapati S (2004)	2
TRIM25	5	MTMR4	1	affinity chromatography technology	Choudhury NR (2017)	1
TRIM25	5	RAPGEF2	5	affinity chromatography technology	Choudhury NR (2017)	1