PsyMuKB

PPI network (data source: BioGrid)

A gene is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the mean normalized expression(base 2 log of (TPM+1)) +1 in all brain tissue from GTEx v7 or BrainSpan data.

A protein is determined as “expressed” when its expression values are above the pre-determined cutoff, which is the normalized expression (base 10 log of iBAQ intensity) ≥0.5 in at least one brain tissue from ProteomicsDB data. Otherwise, a gene or protein is determined as either with below-cutoff expressions or no available data.

	The queried gene/protein
	The interacting partner is expressed at mRNA-level
	The interacting partner is expressed at protein-level
	The interacting partner is expressed at both mRNA and protein level
	The interacting partner is with either below-cutoff expressions or no expression data at both mRNA and protein level
	The interacting partner is hit by coding DNMs
	Physical interaction between queried gene/protein and its partner
	Physical interaction between two interacting partners

Symbol A	GeneA coding DNM count	Symbol B	GeneB coding DNM count	Interaction detection method	Publication	Evidence
JUN	0	STAT1	1	affinity chromatography technology, affinity chromatography technology	Zhang X (1999), Zhang X (1999)	2
BMX	0	STAT3	0	affinity chromatography technology, two hybrid, two hybrid, two hybrid	Tsai YT (2000), Rolland T (2014), Grossmann A (2015), Yu H (2011)	4
STAT3	0	PIAS3	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid	Wang LH (2001), Okumura F (2010), Yamamoto T (2003), Yamamoto T (2003), Tsuruma R (2008), Liu B (1998), Wang J (2011)	7
HIF1A	1	NCOA1	6	pull down	Carrero P (2000)	1
JAK2	1	EGFR	5	affinity chromatography technology, affinity chromatography technology, unspecified method, enzymatic study	Olayioye MA (1999), Olayioye MA (1999), Jones RB (2006), He K (2013)	4
RELA	1	HIF1A	1	affinity chromatography technology, affinity chromatography technology	Yang W (2012), Yang W (2012)	2
SP1	0	SMARCA4	19	pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kadam S (2000), Liu H (2002), Liu H (2002), Ma Z (2004), Saladi SV (2010)	5
RELA	1	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kiernan R (2003), Zhong H (2002), Zhong H (2002), Zhong H (2002), Zhong H (2002), Ashburner BP (2001), Ashburner BP (2001), OShea JM (2010), OShea JM (2010), Liu Y (2006), Cao W (2006), Hu J (2004), Hu J (2004), Sun JM (2007), Deckmann K (2012)	15
NFKB1	2	EP300	36	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology	Deng WG (2003), Deng WG (2003), Furia B (2002), Wang H (2010), Wang H (2010), Sen GS (2011), Hassa PO (2003), Hassa PO (2003), Deng WG (2003)	9
STAT3	0	CDK9	3	affinity chromatography technology, affinity chromatography technology, pull down	Giraud S (2004), Giraud S (2004), Giraud S (2004)	3
SP1	0	EP300	36	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, enzymatic study, affinity chromatography technology, two hybrid, imaging technique, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Gao J (2009), Goto T (2006), Hung JJ (2006), Hung JJ (2006), Hung JJ (2006), Choi HS (2002), Walker GE (2001), Kundu TK (2000), Suzuki T (2000), Suzuki T (2000), Wang X (2008), Wang X (2008), Wang X (2008), Chen YJ (2007), Chen YJ (2007), Azahri NS (2012), Azahri NS (2012), Li J (2013), Li J (2013), Wang SA (2014)	20
NR3C1	2	JUN	0	pull down	Lerner L (2003)	1
NFKBIZ	5	NFKB1	2	affinity chromatography technology, two hybrid	Yamazaki S (2001), Wang J (2011)	2
MYOD1	0	EP300	36	pull down, genetic interference, pull down, pull down, pull down, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down	Lau P (1999), Sartorelli V (1997), Sartorelli V (1997), Sartorelli V (1997), Magenta A (2003), Serra C (2007), Jin W (2011), Yuan W (1996), Yuan W (1996)	9
HIC1	1	STAT3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Lin YM (2013), Lin YM (2013), Lin YM (2013), Lin YM (2013), Hu B (2016), Hu B (2016)	6
EP300	36	PELP1	3	affinity chromatography technology, affinity chromatography technology	Vadlamudi RK (2001), Vadlamudi RK (2001)	2
STAT3	0	RB1	2	affinity chromatography technology, affinity chromatography technology, imaging technique, pull down	Barre B (2005), Barre B (2005), Barre B (2005), Barre B (2005)	4
RPA2	0	STAT3	0	two hybrid, pull down, affinity chromatography technology	Kim J (2000), Kim J (2000), Kim J (2000)	3
BMX	0	SRC	2	affinity chromatography technology	Tsai YT (2000)	1
AR	3	HDAC1	4	two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Gaughan L (2002), Gaughan L (2002), Gaughan L (2005), Gaughan L (2005), Gobinet J (2005), Peche LY (2015)	6
STAT3	0	ELP2	1	two hybrid, pull down, affinity chromatography technology	Collum RG (2000), Collum RG (2000), Collum RG (2000)	3
SRC	2	EGFR	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology, two hybrid	Olayioye MA (1999), Keely SJ (2000), Sato K (2000), Lee CW (2007), Jaganathan S (2011), Jaganathan S (2011), Lee IT (2010), Hitosugi T (2007), Chang CC (2012), Chang CC (2012), Tung WH (2011), Kotlyar M (2015), Petschnigg J (2014), Li J (2013), Yao Z (2017)	15
STAT3	0	DNMT1	5	affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Zhang Q (2005), Zhang Q (2005), Zhang Q (2005), Xing WJ (2015)	4
JAK1	6	STAT3	0	pull down, affinity chromatography technology, affinity chromatography technology	Ueda T (2002), Spiekermann K (2001), Andl CD (2004)	3
SP1	0	AR	3	affinity chromatography technology, affinity chromatography technology	Yuan H (2005), Chen PH (2008)	2
AR	3	PIAS3	2	two hybrid	Kotaja N (2000)	1
HDAC1	4	HIF1A	1	pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Mahon PC (2001), Yoo YG (2006), Kim SH (2007), Kim SH (2007), Bodily JM (2011), Yeh IJ (2013), Yeh IJ (2013)	7
SRC	2	RET	3	affinity chromatography technology	Melillo RM (1999)	1
NR3C1	2	SRC	2	unspecified method	Suino-Powell K (2008)	1
RB1	2	AR	3	pull down, pull down, two hybrid, affinity chromatography technology	Lu J (1998), Yeh S (1998), Yeh S (1998), Gamble SC (2007)	4
HDAC1	4	TRIM28	1	affinity chromatography technology, affinity chromatography technology, biochemical	Allouch A (2011), Chen L (2012), Kristensen AR (2012)	3
RELA	1	JUN	0	two hybrid, genetic interference	Yang X (1999), Yang X (1999)	2
AR	3	NCOA1	6	two hybrid, pull down, two hybrid, affinity chromatography technology, two hybrid, two hybrid, pull down, two hybrid	Masiello D (2004), Bevan CL (1999), Bevan CL (1999), Ueda T (2002), Needham M (2000), Wolf SS (2007), Wolf SS (2007), Chan CM (2013)	8
CCND1	1	STAT3	0	affinity chromatography technology, pull down, affinity chromatography technology	Bienvenu F (2001), Bienvenu F (2005), Bienvenu F (2005)	3
EP300	36	HDAC1	4	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology	Han Y (2008), Mayanil CS (2006), Simone C (2004), Simone C (2004), Simone C (2004), Liu Y (2012), Mizuguchi Y (2012)	7
SP1	0	DNMT1	5	affinity chromatography technology, affinity chromatography technology	Esteve PO (2007), Esteve PO (2007)	2
HDAC1	4	HES1	0	affinity chromatography technology	Shen Q (2005)	1
SP1	0	MYOD1	0	two hybrid	Biesiada E (1999)	1
RPA2	0	EGFR	5	affinity chromatography technology	Marechal A (2014)	1
TRIM28	1	STAT3	0	affinity chromatography technology, pull down, affinity chromatography technology	Tsuruma R (2008), Tsuruma R (2008), Tsuruma R (2008)	3
NFKB1	2	RELA	1	affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, imaging technique, pull down, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Bouwmeester T (2004), Palvimo JJ (1996), Dhar SK (2006), Williams SA (2006), Williams SA (2006), Hassa PO (2005), Hassa PO (2005), Sasaki CY (2005), Jeon YJ (2010), Urban MB (1991), Beauchef G (2012), Ryo A (2003), Burstein E (2005), Beinke S (2002), Sharif-Askari E (2010), Mifflin RC (2002), Nie M (2003), Nehra R (2010), Wang J (2011), Mellits KH (1993), Gallois C (1998), Milanovic M (2013), Milanovic M (2013), Kwon JH (2003), Cimen I (2011), Saha RN (2007), Wi SM (2014), Wi SM (2014), Hochrainer K (2012), Longoni N (2013), Li X (2015)	31
NCOA1	6	STAT3	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Giraud S (2002), Giraud S (2002), Zhang Y (2007), Zhang Y (2007)	4
HDAC3	5	HIF1A	1	pull down, affinity chromatography technology, pull down	Mahon PC (2001), Kim SH (2007), Kim SH (2007)	3
SMARCA4	19	STAT1	1	imaging technique, affinity chromatography technology, affinity chromatography technology	Ni Z (2005), Cheng MB (2010), Zhang Y (2010)	3
HDAC3	5	SP1	0	affinity chromatography technology	Huang W (2006)	1
FGFR1	2	SRC	2	affinity chromatography technology, affinity chromatography technology	Dudka AA (2010), Vecchione A (2007)	2
SP1	0	RELA	1	affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kuang PP (2002), Sif S (1994), Sif S (1994), Kao YS (2008), Kao YS (2008), Benjamin JT (2010), Beauchef G (2012), Xu Y (2008)	8
SP1	0	CCND1	1	affinity chromatography technology	Opitz OG (2000)	1
HIF1A	1	RB1	2	unspecified method, pull down, affinity chromatography technology	Budde A (2005), Budde A (2005), Budde A (2005)	3
SRC	2	PELP1	3	affinity chromatography technology, pull down	Unni E (2004), Barletta F (2004)	2
EP300	36	HDAC6	0	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, pull down	Han Y (2009), Han Y (2009), Liu Y (2012), Kirilyuk A (2012), Girdwood D (2003)	5
STAT3	0	NFKBIZ	5	two hybrid, affinity chromatography technology, affinity chromatography technology, genetic interference, two hybrid	Wu Z (2009), Wu Z (2009), Wu Z (2009), Wu Z (2009), Wang J (2011)	5
EGFR	5	HDAC1	4	affinity chromatography technology	Yao Z (2017)	1
NCOA1	6	CCND1	1	affinity chromatography technology, pull down	Zwijsen RM (1998), Zwijsen RM (1998)	2
JUN	0	HIF1A	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Alfranca A (2002), Yu B (2009), Yu B (2009)	3
MAP3K7	2	RELA	1	imaging technique	Chen TC (2014)	1
STAT3	0	STAT3	0	affinity chromatography technology, affinity chromatography technology, two hybrid, pull down	Yuan ZL (2005), Vogt M (2011), Wang J (2011), Ghosh MK (2005)	4
STAT3	0	MYOD1	0	affinity chromatography technology, affinity chromatography technology, pull down	Kataoka Y (2003), Kataoka Y (2003), Kataoka Y (2003)	3
EP300	36	SRC	2	affinity chromatography technology, affinity chromatography technology	Paladino D (2016), Paladino D (2016)	2
CDK9	3	TRIM28	1	affinity chromatography technology	Jeronimo C (2007)	1
RB1	2	PELP1	3	affinity chromatography technology, pull down	Balasenthil S (2003), Balasenthil S (2003)	2
SRC	2	STAT1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Olayioye MA (1999), Cirri P (1997), Chang YJ (2004), Chang YJ (2004)	4
EGFR	5	TRIM28	1	affinity chromatography technology	Liccardi G (2014)	1
SRC	2	JAK2	1	affinity chromatography technology	Liang K (2010)	1
NR3C1	2	EP300	36	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Amat R (2007), Wang W (2012), Kino T (2002)	3
EGFR	5	HDAC6	0	affinity chromatography technology, protein complementation assay, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Gao YS (2010), Deribe YL (2009), Deribe YL (2009), Deribe YL (2009), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	7
HDAC1	4	STAT1	1	affinity chromatography technology	Kraemer OH (2006)	1
HES1	0	STAT3	0	affinity chromatography technology, pull down, enzymatic study	Kamakura S (2004), Kamakura S (2004), Kamakura S (2004)	3
NR3C1	2	HDAC6	0	affinity chromatography technology, affinity chromatography technology, pull down	Govindan MV (2010), Govindan MV (2010), Govindan MV (2010)	3
HES1	0	JAK2	1	affinity chromatography technology	Kamakura S (2004)	1
SP1	0	HIC1	1	imaging technique	Sun L (2013)	1
HIF1A	1	TRIM28	1	affinity chromatography technology	Cai Q (2013)	1
AR	3	SMARCA4	19	affinity chromatography technology, two hybrid, affinity chromatography technology, bioid	Wang Q (2004), van de Wijngaart DJ (2009), Dai Y (2008), Lempiaeinen JK (2017)	4
NR3C1	2	STAT3	0	pull down, affinity chromatography technology, affinity chromatography technology	Lerner L (2003), Zhang Z (1997), Wang W (2015)	3
HIF1A	1	STAT3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Jung JE (2008), Jung JE (2008), Gray MJ (2005), Gray MJ (2005), Pawlus MR (2013), Pawlus MR (2013)	6
RB1	2	HDAC1	4	affinity chromatography technology, pull down, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology	Dick FA (2000), Fuks F (2000), Puri PL (2001), Puri PL (2001), Wang S (2002), Luo RX (1998), Luo RX (1998), Lai A (1999), Lai A (1999), Ferreira R (1998), Kimura H (2003), Qiu Z (2008), Fedele M (2006), Brown VD (2002), Khan MM (2001), Dasgupta P (2004), Chang YC (2001), Dahiya A (2000), Zhang HS (2000), Tokitou F (1999), Nguyen DX (2004), Takaki T (2004), Magnaghi-Jaulin L (1998), Magnaghi-Jaulin L (1998), Brehm A (1998), Brehm A (1998), Brehm A (1998), Sun JM (2007), Fan LX (2012), Harbour JW (1999), Brehm A (1999), Joshi P (2013), Chen TT (2000), Chen TT (2000), Chen TT (2000), Chen TT (2000)	36
JUN	0	STAT3	0	affinity chromatography technology, affinity chromatography technology, pull down	Zhang X (1999), Zhang X (1999), Zhang X (1999)	3
SP1	0	RB1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Singh J (2002), Chang YC (2001), Opitz OG (2000)	3
HDAC6	0	HIF1A	1	affinity chromatography technology	Qian DZ (2006)	1
TRIM28	1	DNMT1	5	affinity chromatography technology, affinity chromatography technology	Quenneville S (2011), Cui S (2011)	2
STAT3	0	MAP3K7	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kojima H (2005), Kojima H (2005), Kojima H (2005)	3
STAT3	0	HDAC3	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yuan ZL (2005), Yuan ZL (2005), Gupta M (2011), Tsuruma R (2008), Kato M (2015)	5
ELP2	1	JAK1	6	affinity chromatography technology, pull down	Collum RG (2000), Collum RG (2000)	2
SP1	0	STAT3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Lin S (2006), Zhang Y (2007), Zhang Y (2007), Proietti CJ (2011)	4
AR	3	HDAC3	5	pull down, affinity chromatography technology	Franco PJ (2003), Zhu P (2006)	2
RELA	1	AR	3	genetic interference, genetic interference	Aarnisalo P (1998), Aarnisalo P (1998)	2
HDAC3	5	SMARCA4	19	affinity chromatography technology, affinity chromatography technology	Qiu Z (2008), Zhu P (2006)	2
RELA	1	PIAS3	2	two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, enzymatic study	Jang HD (2004), Jang HD (2004), Jang HD (2004), Jang HD (2004), Liu Y (2012)	5
EP300	36	HDAC3	5	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down	Kadeppagari RK (2009), Gregoire S (2007), Gregoire S (2007), Sankar N (2008), Sankar N (2008)	5
JUN	0	HDAC1	4	affinity chromatography technology	Tenbrock K (2006)	1
DNMT1	5	HDAC3	5	affinity chromatography technology, affinity chromatography technology	Cui S (2011), Cui S (2011)	2
RB1	2	EP300	36	affinity chromatography technology, affinity chromatography technology, enzymatic study	Iyer NG (2007), Iyer NG (2007), Chan HM (2001)	3
HIF1A	1	SMARCA4	19	imaging technique	Wang F (2004)	1
ELP2	1	STAT1	1	pull down	Collum RG (2000)	1
RB1	2	CDK9	3	pull down, affinity chromatography technology, enzymatic study, enzymatic study, biochemical, enzymatic study	Simone C (2002), Simone C (2002), De Luca A (1997), Garriga J (1996), Garriga J (1996), Grana X (1994)	6
EGFR	5	BMX	0	unspecified method	Jones RB (2006)	1
STAT3	0	NFKB1	2	affinity chromatography technology, pull down, imaging technique	Yu Z (2002), Yu Z (2002), Chen TC (2014)	3
HDAC3	5	TRIM28	1	affinity chromatography technology	Tsuruma R (2008)	1
AR	3	STAT3	0	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Matsuda T (2001), Ueda T (2002), Yamamoto T (2003), Yamamoto T (2003)	4
FGFR1	2	JAK2	1	affinity chromatography technology	Dudka AA (2010)	1
NR3C1	2	NCOA1	6	pull down, two hybrid, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, bioid	Zilliacus J (2001), Kucera T (2002), Windahl SH (1999), Fryer CJ (1998), Needham M (2000), Li G (2006), Lempiaeinen JK (2017)	7
AR	3	EP300	36	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology	Dai Y (2008), Minges JT (2013), Zhong J (2014), Fu M (2000), McClurg UL (2016), Tan G (2017)	6
CCND1	1	RB1	2	pull down, genetic interference, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study, enzymatic study	Siegert JL (2000), Siegert JL (2000), Dowdy SF (1993), Chan HM (2001), Dasgupta P (2004), Dasgupta P (2004), Sweeney KJ (1997), Higashi H (1996), Musgrove EA (1996), Yarbrough WG (1999), Connell-Crowley L (1997), Kitagawa M (1996), Poon RY (1996), Gaiddon C (2003), Zarkowska T (1997), Nakanishi M (1999), Welcker M (1998)	17
CCND1	1	HDAC3	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology	Petre-Draviam CE (2005), Lin HM (2002), Fu M (2005), Fu M (2005), Batra S (2010)	5
EP300	36	PIAS3	2	affinity chromatography technology	Long J (2004)	1
JUN	0	MYOD1	0	affinity chromatography technology, pull down	Bengal E (1992), Bengal E (1992)	2
EGFR	5	STAT3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, two hybrid, imaging technique, protein complementation assay, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Yuan ZL (2004), Olayioye MA (1999), Lo HW (2005), Lo HW (2005), Crovello CS (1998), Jaganathan S (2011), Jaganathan S (2011), Andl CD (2004), Lo HW (2010), Foerster S (2013), Kotlyar M (2015), Chen TC (2014), Petschnigg J (2014), Petschnigg J (2014), Li J (2013), de la Iglesia N (2008), Fan QW (2013), Fan QW (2013)	18
JAK2	1	STAT3	0	affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology, enzymatic study, enzymatic study, affinity chromatography technology	Ram PA (1997), Manea A (2010), Andl CD (2004), Kamakura S (2004), He K (2013), Kucia-Tran JA (2016), M L (2016)	7
NR3C1	2	NFKB1	2	pull down, affinity chromatography technology	Scheinman RI (1995), Ito K (2006)	2
CCND1	1	AR	3	affinity chromatography technology, pull down, affinity chromatography technology	Petre-Draviam CE (2005), Petre-Draviam CE (2005), Knudsen KE (1999)	3
STAT3	0	STAT1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, pull down, affinity chromatography technology	Gunaje JJ (2001), Spiekermann K (2001), Xia L (2002), Chen TC (2014), Li X (2015), Ghosh MK (2005), Huttlin EL (2017)	7
EGFR	5	RET	3	two hybrid, protein complementation assay, affinity chromatography technology, affinity chromatography technology	Kotlyar M (2015), Petschnigg J (2014), Bhinge K (2017), Bhinge K (2017)	4
HIF1A	1	SRC	2	imaging technique, affinity chromatography technology	Gray MJ (2005), Ruas JL (2005)	2
CDK9	3	FGFR1	2	affinity chromatography technology	Varjosalo M (2013)	1
TRIM28	1	NR3C1	2	affinity chromatography technology, pull down, biochemical	Chang CJ (1998), Chang CJ (1998), Kristensen AR (2012)	3
HDAC1	4	NFKB1	2	affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, imaging technique, imaging technique, affinity chromatography technology, imaging technique	Zhong H (2002), Zhong H (2002), Zhong H (2002), Viatour P (2003), Williams SA (2006), Williams SA (2006), Sun JM (2007), Chen TC (2014)	8
HDAC3	5	RB1	2	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Fajas L (2002), Lai A (1999), Lai A (1999), Dahiya A (2000)	4
FGFR1	2	STAT3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Dudka AA (2010), Dudka AA (2010), Dudka AA (2010)	3
PIAS3	2	HIC1	1	imaging technique	Sun L (2013)	1
SRC	2	AR	3	affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid	Migliaccio A (2000), Unni E (2004), Powell SM (2004), Dotzlaw H (2003)	4
EP300	36	STAT1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Paulson M (1999), Hiroi M (2003), Ray S (2002), Strassheim D (2009), Liu X (2008), Ghosh AK (2001), Yang WS (2005), Zhang Y (2015), Kotla S (2015), Kotla S (2015)	10
DNMT1	5	RB1	2	biochemical, pull down, affinity chromatography technology, pull down, affinity chromatography technology	Robertson KD (2000), Robertson KD (2000), Robertson KD (2000), Pradhan S (2002), Pradhan S (2002)	5
RET	3	STAT3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Yuan ZL (2004), Hwang JH (2003), Schuringa JJ (2001), Chen TC (2014)	4
SRI	1	STAT3	0	affinity chromatography technology, two hybrid, two hybrid	Wang J (2011), Wang J (2011), DeGrado-Warren J (2008)	3
SMARCA4	19	STAT3	0	affinity chromatography technology, affinity chromatography technology, pull down	Giraud S (2004), Giraud S (2004), Giraud S (2004)	3
ELP2	1	JAK2	1	affinity chromatography technology	Collum RG (2000)	1
JUN	0	RB1	2	affinity chromatography technology, pull down, two hybrid, affinity chromatography technology, pull down	Nishitani J (1999), Nishitani J (1999), Nishitani J (1999), Nead MA (1998), Nead MA (1998)	5
NCOA1	6	NFKB1	2	pull down, pull down	Lee SK (2000), Na SY (1998)	2
HDAC6	0	RELA	1	affinity chromatography technology	Yang CJ (2015)	1
JAK2	1	STAT1	1	affinity chromatography technology, affinity chromatography technology, imaging technique, affinity chromatography technology, affinity chromatography technology	Cheng MB (2010), Cheng MB (2010), Manea A (2010), Andl CD (2004), Chang YJ (2004)	5
DNMT1	5	HIC1	1	affinity chromatography technology, affinity chromatography technology	Zeng S (2016), Zeng S (2016)	2
PELP1	3	STAT3	0	two hybrid, affinity chromatography technology, pull down	Manavathi B (2005), Manavathi B (2005), Manavathi B (2005)	3
RPA2	0	TRIM28	1	affinity chromatography technology	Marechal A (2014)	1
STAT1	1	MTOR	14	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, biochemical, affinity chromatography technology, imaging technique	Kristof AS (2003), Kristof AS (2003), Fielhaber JA (2009), Fielhaber JA (2009), Fielhaber JA (2009), Chen TC (2014)	6
EP300	36	RELA	1	enzymatic study, two hybrid, affinity chromatography technology, genetic interference, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Kiernan R (2003), Gerritsen ME (1997), Gerritsen ME (1997), Gerritsen ME (1997), Gerritsen ME (1997), Hiroi M (2003), Nicot C (2001), Kim RH (2001), Hassa PO (2008), Hassa PO (2008), Hu J (2004), Naeaer AM (1999), Lee IT (2010), Nehra R (2010), Hsu HC (2007), Hsu HC (2007), Saha RN (2007), Saha RN (2007), Hassa PO (2003), Hassa PO (2003), Mendonca DB (2011), Chen W (2008), Chen LF (2002), OHara A (2014), Lu Y (2013), Lu Y (2013), Ren YB (2015), Chen LF (2005), Chen LF (2005), Chen LF (2005), Deng WG (2003)	31
HDAC1	4	SMARCA4	19	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, genetic interference	Qiu Z (2008), Battaglioli E (2002), Hang CT (2010), DiRenzo J (2000)	4
EP300	36	CCND1	1	pull down, affinity chromatography technology, affinity chromatography technology	Ratineau C (2002), Fu M (2005), Fu M (2005)	3
HDAC6	0	HES1	0	two hybrid	Vinayagam A (2011)	1
SP1	0	JUN	0	pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology	Kardassis D (1999), Hung JJ (2006), Chen BK (2007), Chen BK (2007), Chen BK (2007)	5
RELA	1	CCND1	1	affinity chromatography technology	Veena MS (2014)	1
MAGEC2	0	STAT3	0	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Song X (2017), Song X (2017), Song X (2017), Song X (2017)	4
HDAC1	4	MYOD1	0	pull down, affinity chromatography technology, pull down, affinity chromatography technology	Puri PL (2001), Puri PL (2001), Mal A (2001), Bruscoli S (2010)	4
JAK1	6	STAT1	1	affinity chromatography technology, affinity chromatography technology	Andl CD (2004), Chang YJ (2004)	2
SMARCA4	19	NCOA1	6	genetic interference	DiRenzo J (2000)	1
HDAC3	5	JUN	0	affinity chromatography technology	Weiss C (2003)	1
DNMT1	5	HDAC1	4	biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Robertson KD (2000), Achour M (2008), Achour M (2008), Kimura H (2003), Zhang Q (2005), Myant K (2008), Schnekenburger M (2007), Kang KA (2012), Cui S (2011), Cui S (2011), Hervouet E (2010), Cai Y (2014), Cai Y (2014), Yuan K (2016), Yuan K (2016)	15
NR3C1	2	RELA	1	affinity chromatography technology, pull down, pull down	Ray A (1994), Nissen RM (2000), Caldenhoven E (1995)	3
MTOR	14	STAT3	0	pull down, affinity chromatography technology, affinity chromatography technology	Yokogami K (2000), Kusaba H (2005), Yang F (2013)	3
RELA	1	HDAC3	5	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Chen Lf (2001), Chen Lf (2001), Hu J (2004), Hu J (2004)	4
EGFR	5	NR3C1	2	two hybrid, protein complementation assay, affinity chromatography technology	Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	3
TRIM28	1	STAT1	1	affinity chromatography technology, affinity chromatography technology	Kamitani S (2008), Tsuruma R (2008)	2
STAT1	1	RELA	1	imaging technique	Chen TC (2014)	1
STAT3	0	RELA	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Yu Z (2002), Yu Z (2002), Yoshida Y (2004), Yoshida Y (2004), Dhar K (2013)	5
RPA2	0	PELP1	3	affinity chromatography technology	Marechal A (2014)	1
MTOR	14	EP300	36	enzymatic study	Wan W (2017)	1
EP300	36	HIF1A	1	affinity chromatography technology, x-ray crystallography, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, two hybrid, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, pull down, unspecified method, affinity chromatography technology, fluorescent resonance energy transfe, pull down, affinity chromatography technology, affinity chromatography technology, pull down, unspecified method, pull down, affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, pull down, pull down	Lando D (2002), Freedman SJ (2002), Lewis MD (2004), Matt T (2004), Sang N (2002), Luo W (2010), Freedman SJ (2003), Bodily JM (2011), Lee YM (2009), Lee YM (2009), Lee YM (2009), Kung AL (2004), Kung AL (2004), Kung AL (2004), Land SC (2007), Zhang Y (2010), Zhang Y (2010), Fath DM (2006), Fath DM (2006), Lee SJ (2013), Wang D (2014), Kaluz S (2006), Kaluz S (2006), Kaluz S (2006), Shin DH (2008), Shin DH (2008), Wang Y (2012), Huang C (2009), Hewitson KS (2002), Cook KM (2009), Cook KM (2009), Hubbi ME (2012), Kim SY (2014), Sang N (2003), Sang N (2003), Sang N (2003), Yasinska IM (2003), Na YR (2013), Na YR (2013), Mendonca DB (2011), Arany Z (1996), Arany Z (1996), Chen R (2012), Li SH (2008), Galbraith MD (2013), Chen Z (2014), Li Q (2012), Geng H (2012), Geng H (2012), Kato H (2004), Lim JH (2010), Kyle HF (2015), Kyle HF (2015), Rath S (2016), Kimura M (2008), Dubey R (2013)	56
NFKB1	2	PELP1	3	pull down	Miyamoto-Sato E (2010)	1
NR3C1	2	HDAC1	4	affinity chromatography technology, affinity chromatography technology, biochemical, fluorescent resonance energy transfe, pull down	Qiu Y (2006), Jee YK (2005), Kristensen AR (2012), Qiu Y (2011), Qiu Y (2011)	5
STAT3	0	EP300	36	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Nakashima K (1999), Nakashima K (1999), Ray S (2002), Ray S (2002), Yuan ZL (2005), Yuan ZL (2005), Gupta M (2011), Wang R (2005), Gray MJ (2005), Hou T (2008), Kotla S (2015)	11
EGFR	5	AR	3	affinity chromatography technology, affinity chromatography technology, imaging technique, imaging technique	Bonaccorsi L (2004), Bonaccorsi L (2004), Bonaccorsi L (2004), Bonaccorsi L (2004)	4
SP1	0	NFKB1	2	pull down, affinity chromatography technology, affinity chromatography technology	Sif S (1994), Dhar SK (2006), Liu S (2008)	3
JUN	0	AR	3	affinity chromatography technology, affinity chromatography technology	Sato N (1997), Sato N (1997)	2
MYOD1	0	SMARCA4	19	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Philipot O (2010), de la Serna IL (2005), Forcales SV (2012)	3
SP1	0	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Di Padova M (2003), Singh J (2002), Zhang Y (2002), Sun JM (2002), Gao J (2009), Shon JK (2009), Mottet D (2009), Goto T (2006), Hung JJ (2006), Lagger G (2003), Choi HS (2002), Choi HS (2002), Kang JE (2005), Kang JE (2005), Kang JE (2005), Gan Y (2005), Gan Y (2005), Duan H (2005), Varshochi R (2005), Varshochi R (2005), Plaisance V (2005), Walker GE (2001), Walker GE (2001), Ammanamanchi S (2004), Doetzlhofer A (1999), Sekhavat A (2007), Liu T (2007), Enya K (2008), Liu S (2010), Leclerc GJ (2010), Leclerc GJ (2010), Wong CY (2011), Schnur N (2007)	33
MAGEC2	0	TRIM28	1	affinity chromatography technology, affinity chromatography technology, pull down, pull down, affinity chromatography technology, two hybrid, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Doyle JM (2010), Doyle JM (2010), Doyle JM (2010), Doyle JM (2010), Bhatia N (2011), Bhatia N (2011), Bhatia N (2013), Hao J (2014), Song X (2017), Jin X (2017)	10
CDK9	3	AR	3	affinity chromatography technology, pull down	Lee DK (2001), Lee DK (2001)	2
CDK9	3	RELA	1	pull down, affinity chromatography technology	Amini S (2002), Amini S (2002)	2
HDAC3	5	NFKB1	2	affinity chromatography technology, imaging technique	Viatour P (2003), Hoberg JE (2004)	2
EP300	36	JUN	0	pull down, biochemical, x-ray crystallography, affinity chromatography technology, pull down, enzymatic study, pull down, imaging technique, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology	Campbell KM (2002), Campbell KM (2002), Campbell KM (2002), Subbaramaiah K (2002), Duyndam MC (1999), Wang WM (2011), Deng WG (2004), Deng WG (2004), Cheng SE (2011), Cheng SE (2011), Kim BK (2014), Vries RG (2001), Deng WG (2003), Liu L (2017), Liu L (2017)	15
SRC	2	STAT3	0	affinity chromatography technology, pull down, pull down, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique, pull down	Cao X (1996), Cao X (1996), Yin N (2004), Yin N (2004), Jaganathan S (2011), Jaganathan S (2011), Gray MJ (2005), Schreiner SJ (2002)	8
SRC	2	HDAC3	5	affinity chromatography technology, affinity chromatography technology, enzymatic study, affinity chromatography technology	Longworth MS (2006), Longworth MS (2006), Longworth MS (2006), Matteucci E (2007)	4
HDAC1	4	CCND1	1	affinity chromatography technology, imaging technique, affinity chromatography technology	Fu M (2005), Fu M (2005), Batra S (2010)	3
HDAC6	0	JAK2	1	affinity chromatography technology	M L (2016)	1
HDAC3	5	STAT1	1	affinity chromatography technology	Kraemer OH (2006)	1
NCOA1	6	EP300	36	affinity chromatography technology, imaging technique, pull down, pull down	Matsuda S (2004), Wang F (2010), Kino T (2002), Nasrin N (2000)	4
EGFR	5	MTOR	14	affinity chromatography technology	Foerster S (2013)	1
HDAC6	0	STAT3	0	affinity chromatography technology, affinity chromatography technology, imaging technique	M L (2016), M L (2016), M L (2016)	3
NR3C1	2	SMARCA4	19	affinity chromatography technology, pull down, biochemical, affinity chromatography technology, bioid	Hsiao PW (2003), Wallberg AE (2000), Reyes JC (1997), Xu R (2007), Lempiaeinen JK (2017)	5
EGFR	5	STAT1	1	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, protein complementation assay, affinity chromatography technology	Olayioye MA (1999), Xia L (2002), Andl CD (2004), Foerster S (2013), Tong J (2014), Kotlyar M (2015), Petschnigg J (2014), Petschnigg J (2014)	8
EGFR	5	JAK1	6	affinity chromatography technology	Tong J (2008)	1
MYOD1	0	RB1	2	pull down, pull down, affinity chromatography technology	Mal A (2001), Gu W (1993), Gu W (1993)	3
AR	3	PELP1	3	affinity chromatography technology	Unni E (2004)	1
TRIM28	1	SMARCA4	19	affinity chromatography technology	Seki Y (2010)	1
RB1	2	SMARCA4	19	affinity chromatography technology, biochemical, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology	Dunaief JL (1994), Reyes JC (1997), Qiu Z (2008), Dasgupta P (2004), Zhang HS (2000), Zhang HS (2000), Napolitano MA (2007), Dunaief JL (2002), Tu Z (2013)	9
STAT3	0	HDAC1	4	affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, imaging technique	Zhang Q (2005), Yuan ZL (2005), Gupta M (2011), Zhi Y (2012), Zhi Y (2012)	5
SP1	0	HIF1A	1	affinity chromatography technology, pull down, affinity chromatography technology, affinity chromatography technology, pull down, imaging technique	To KK (2006), To KK (2006), Sanchez-Elsner T (2002), Sanchez-Elsner T (2002), Koshiji M (2005), Koshiji M (2005)	6
NCOA1	6	JUN	0	pull down, pull down, two hybrid, pull down	Lee SK (1999), Lee SK (2000), Lee SK (1998), Lee SK (1998)	4