Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
TNFRSF11A 8792 CHEMBL300914 CHEMBL300914 GuideToPharmacologyInteractions
TNFRSF11A 8792 ZOLEDRONIC ACID CHEMBL924 PharmGKB

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
TNFRSF11A rs12969154 G alendronate efficacy no Allele G is not associated with response to alendronate in women with Osteoporosis as compared to allele A. 26426211 1446907672
TNFRSF11A rs8083511 A alendronate efficacy no Allele A is not associated with response to alendronate in women with Osteoporosis as compared to allele C. 26426211 1446907715
TNFRSF11A rs7231887 G alendronate efficacy no Allele G is not associated with response to alendronate in women with Osteoporosis as compared to allele A. 26426211 1446907736
TNFRSF11A rs3826619 G alendronate efficacy no Allele G is not associated with response to alendronate in women with Osteoporosis as compared to allele A. 26426211 1446907679
TNFRSF11A rs7239261 A alendronate efficacy no Allele A is not associated with response to alendronate in women with Osteoporosis as compared to allele C. 26426211 1446907665
TNFRSF11A rs2980976 A risperidone efficacy yes The number of A alleles present in a patient was positively associated with CGI-S score. Allele A is associated with decreased response to risperidone in people with Schizophrenia as compared to allele G. 23241943 1450815009
TNFRSF11A rs1805034 C alendronate efficacy no Allele C is not associated with response to alendronate in women with Osteoporosis as compared to allele T. 26426211 1446907702
TNFRSF11A rs11877530 G alendronate efficacy no Allele G is not associated with response to alendronate in women with Osteoporosis as compared to allele A. 26426211 1446907687
TNFRSF11A rs17069895 C alendronate efficacy no Allele C is not associated with response to alendronate in women with Osteoporosis as compared to allele T. 26426211 1446907728