Gene-drug interactions (data source: DGIdb)
Gene Name Entrez ID Drug Name Chembl ID Interaction Types Sources publications
SLC22A6 9356 BUPROPION HYDROCHLORIDE CHEMBL1698 blocker TTD
SLC22A6 9356 CEFOTAXIME CHEMBL1730 DrugBank 11909604
SLC22A6 9356 PRATOSARTAN CHEMBL41194 inhibitor ChemblInteractions
SLC22A6 9356 PROBENECID CHEMBL897 inhibitor, blocker GuideToPharmacologyInteractions, ChemblInteractions, DrugBank, TTD 11669456, 15377641, 11752352, 12130730, 11426832
SLC22A6 9356 CIDOFOVIR CHEMBL152 PharmGKB

Variant-drug associations (data source: PharmGKB)
Gene Name Variant Alleles Chemical Phenotype Category Significance Notes Sentence Publications Annotation ID
SLC22A6 rs11568634 T adefovir dipivoxil other no In the clinical study consist of 4 individuals in a family, there was no significant decrease in the renal secretory clearance of adefovir in family members heterozygous for OAT1-454Q in comparison to those with the reference transporter, OAT1-454R. Allele T is not associated with clearance of adefovir dipivoxil as compared to allele C. 15864112 1449753015